Khanspers

ADHD and autism (ASD) linked metabolic pathways and SNP

Affected pathways in Duchenne muscular dystrophy

Th17 cell differentiation pathway

Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Blood clotting cascade

Cardiac progenitor differentiation

IL-19 signaling pathway

Glycolysis in senescence

Carnosine metabolism of glial cells

Kynurenine pathway and links to cell senescence

Nucleotide excision repair

Base excision repair

Fragile X syndrome

Non-homologous end joining

Wnt signaling pathway and pluripotency

N-glycan biosynthesis

Pentose phosphate pathway in senescent cells

Prion disease pathway

Smith-Magenis and Potocki-Lupski syndrome copy number variation

TCA cycle

Neurotransmitter disorders

Kennedy pathway from sphingolipids

Hepatitis B infection

Non-small cell lung cancer

Acute myeloid leukemia

NRF2-ARE regulation

Pancreatic adenocarcinoma pathway

Ras signaling

Chromosomal and microsatellite instability in colorectal cancer

PI3K-Akt signaling pathway

Endometrial cancer

17p13.3 (YWHAE) copy number variation

ncRNAs involved in Wnt signaling in hepatocellular carcinoma

lncRNA in canonical Wnt signaling and colorectal cancer

5q35 copy number variation

NF1 copy number variation syndrome

4p16.3 copy number variation

Pleural mesothelioma

Small cell lung cancer

Wnt signaling

Regulation of sister chromatid separation at the metaphase-anaphase transition

Toll-like receptor signaling pathway

Translation inhibitors in chronically activated PDGFRA cells

G1 to S cell cycle control

Breast cancer pathway

Hedgehog signaling pathway

Epithelial to mesenchymal transition in colorectal cancer

Fibrin complement receptor 3 signaling pathway

Clear cell renal cell carcinoma pathways

Bladder cancer

Cell cycle

Osteoblast differentiation and related diseases

FGFR3 signaling in chondrocyte proliferation and terminal differentiation

Transcriptional activation by NRF2 in response to phytochemicals

EGFR tyrosine kinase inhibitor resistance

Head and neck squamous cell carcinoma

PDGFR-beta pathway

TCA cycle nutrient use and invasiveness of ovarian cancer

ErbB signaling pathway

Cancer immunotherapy by PD-1 blockade

Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms

MET in type 1 papillary renal cell carcinoma

MFAP5-mediated ovarian cancer cell motility and invasiveness

Hippo-Merlin signaling dysregulation

Hippo signaling regulation pathways

Hippo-YAP signaling

Measles virus infection

Focal adhesion

Complement system

Prader-Willi and Angelman syndrome

Metabolic Epileptic Disorders

Vitamin K metabolism and activation of dependent proteins

PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer

TCA cycle (plant)

Gibberellin A12 biosynthesis

Aerobic glycolysis

One-carbon metabolism

Alanine and aspartate metabolism

Pathophysiological roles of DUX4 in FSHD1

Mitochondrial fatty acid oxidation disorders

Diet-dependent trimethylamine/trimethylamine N-oxide metabolism

Osteoblast signaling

Genetic alterations of lung cancer

Nicotine effect on chromaffin cells

Osteoclast signaling

ALA oxylipin metabolism

Hypoxia-dependent differentiation of myoblasts

Hypoxia-dependent self-renewal of myoblasts

CAMKK2 pathway

Pre-implantation embryo

Electron transport chain: OXPHOS system in mitochondria

Glycerophospholipid biosynthetic pathway

TROP2 regulatory signaling

Comprehensive IL-17A signaling

Urotensin-II-mediated signaling pathway

ACE inhibitor pathway

Aryl hydrocarbon receptor pathway

IL-26 signaling pathways

Integrated cancer pathway

VEGF-receptor signal transduction

VEGFR-3 signaling

Glucocorticoid effect on target gene expression

Cori cycle

Peroxisomal beta-oxidation of tetracosanoyl-CoA

Apoptosis modulation and signaling

Kennedy pathway

Mechanosensory inputs influence pharyngeal activity via ivermectin sensitivity genes

TP53 network

Iron homeostasis

Folate-alcohol and cancer pathway hypotheses

Type II diabetes mellitus

Transcription factors regulate miRNAs related to cardiac hypertrophy

Metapathway signal transduction

MicroRNAs in cardiomyocyte hypertrophy

Energy metabolism

Flavonoid biosynthesis

miRNA regulation of DNA damage response

Physiological and pathological hypertrophy of the heart

Regulation of cardiac hypertrophy by miR-208

Hedgehog-related genes

Dopaminergic neurogenesis

Oxidative damage response

Glycine metabolism

Opioid receptor pathways

White fat cell differentiation

Dopaminergic neurogenesis

Brain-derived neurotrophic factor (BDNF) signaling pathway

Oncostatin M signaling pathway

Parkinson's disease pathway

Corticotropin-releasing hormone signaling pathway

Interleukin-11 signaling pathway

AGE/RAGE pathway

Thymic stromal lymphopoietin (TSLP) signaling pathway

Heart development

Nicotine effect on dopaminergic neurons

Fluoropyrimidine activity

Mitochondrial long chain fatty acid beta-oxidation

Alpha 6 beta 4 signaling pathway

IL-7 signaling pathway

Target of rapamycin signaling

Photosynthetic carbon reduction

Serotonin transporter activity

IL-4 signaling pathway

VEGFA-VEGFR2 signaling

Apoptosis modulation by HSP70

MAPK signaling pathway

Triacylglyceride synthesis

Osteoblast signaling

Notch signaling

Small ligand GPCRs

Prolactin signaling pathway

TNF-related weak inducer of apoptosis (TWEAK) signaling pathway

Follicle stimulating hormone (FSH) signaling pathway

Leptin signaling pathway

Thyroid stimulating hormone (TSH) signaling pathway

RANKL/RANK signaling pathway

TGF-beta receptor signaling in skeletal dysplasias

IL-18 signaling pathway

Gastrin signaling pathway

Pyrimidine metabolism

Valine, leucine and isoleucine degradation

Androgen receptor signaling pathway

IL-2 signaling pathway

Hedgehog signaling pathway

Adipogenesis genes

EGF/EGFR signaling pathway

mRNA processing

Oxidative stress response

Eukaryotic transcription initiation

p38 MAPK signaling pathway

IL6 signaling pathway

Wnt signaling pathway

Fas ligand pathway and stress induction of heat shock proteins

Kit receptor signaling pathway

Nuclear receptors in lipid metabolism and toxicity

Myometrial relaxation and contraction pathways

IL-3 signaling pathway

S1P receptor signal transduction

TOR signaling

CFTR activity in the plasma membrane

TNF-alpha and mucus production in lung epythelium

Intracellular trafficking of CFTR

Interactions between CFTR and other ion channels

Osteopontin signaling

Nucleotide-binding oligomerization domain (NOD) pathway

Peptide GPCRs

B cell receptor signaling pathway

IL-9 signaling pathway

IL-1 signaling pathway

Homologous recombination

Integrin-mediated cell adhesion

Bone morphogenic protein signaling and regulation

AMP-activated protein kinase signaling

Pentose phosphate metabolism

IL-5 signaling pathway

Translation factors

Interferon type I signaling pathways

TGF-beta receptor signaling

Complement and coagulation cascades

Biogenic amine synthesis

Complement activation

Calcium regulation in cardiac cells

Cytokines and inflammatory response

Hypertrophy model

Glucuronidation

Sulfation biotransformation reaction

Tamoxifen metabolism

T-cell receptor signaling pathway

Arachidonate epoxygenase / epoxide hydrolase

Glucose homeostasis

Abscisic acid biosynthesis

Flower development

Notch signaling pathway

Monoamine GPCRs

ID signaling pathway

Regulation of actin cytoskeleton

Glycogen synthesis and degradation

Prostaglandin synthesis and regulation

Nucleotide GPCRs

Vitamin A and carotenoid metabolism

Estrogen signaling pathway

DNA damage response (only ATM dependent)

DNA damage response

Ovarian infertility

Orexin receptor pathway

Fructose metabolism in proximal tubules

Heme biosynthesis

Disorders of folate metabolism and transport

Vitamin B6-dependent and responsive disorders

Purine metabolism and related disorders

Sialylation

Iron-sulfur cluster biogenesis

Glycolysis and gluconeogenesis

Angiotensin II receptor type 1 pathway

RAS and bradykinin pathways in COVID-19

16p11.2 proximal deletion syndrome

Serotonin receptor 4/6/7 and NR3C signaling

Serotonin receptor 2 and ELK-SRF/GATA4 signaling

Serotonin HTR1 group and FOS pathway

Codeine and morphine metabolism

IL-9 signaling pathway

Amino acid conjugation of benzoic acid

IL-6 signaling pathway

Androgen receptor network in prostate cancer

Metapathway biotransformation

Fatty acid biosynthesis

Mevalonate pathway

Wnt signaling pathway and pluripotency

ATM signaling pathway

Glycerol teichoic acid biosynthesis

Catecholamine synthesis

SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation

Oxidative stress and redox pathway

Flavan-3-ol metabolic pathway

Metabolism of tetrahydrocannabinol (THC)

Cardiac progenitor differentiation

Pentose phosphate pathway

Seed development

Carbon assimilation C4 pathway

Phase I biotransformations, non P450

Oxidation by cytochrome P450

Phase I biotransformations, non P450

Oxidation by cytochrome P450

Phase I biotransformations, non P450

mRNA processing

Ethanol effects on histone modifications

Mitochondrial long chain fatty acid beta-oxidation

Sudden infant death syndrome (SIDS) susceptibility pathways

Aflatoxin B1 metabolism

Heme biosynthesis

Lipid remodeling

Sphingolipid metabolism: integrated pathway

Cholesterol metabolism with Bloch and Kandutsch-Russell pathways

miRNA role in immune response in sepsis

Methionine metabolism leading to sulfur amino acids and related disorders

Degradation pathway of sphingolipids, including diseases

Inflammatory response pathway

Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling

MECP2 and associated Rett syndrome

Nod-like receptor (NLR) signaling pathway

Pregnane X receptor pathway

Glial cell differentiation

Heme biosynthesis

Eicosanoid synthesis

Selenium micronutrient network

Fatty acid beta-oxidation

Folic acid network

Retinol metabolism

Folic acid network

Retinol metabolism

Sulfur amino acid biosynthesis

Statin pathway

Clock-controlled autophagy in bone metabolism

Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins

mRNA processing

Copper homeostasis

Myometrial relaxation and contraction pathways

mRNA processing

Notch signaling pathway

mRNA processing

Myometrial relaxation and contraction pathways

mRNA processing

mRNA Processing

Homologous recombination

Vitamin D in inflammatory diseases

Resistin as a regulator of inflammation

Altered glycosylation of MUC1 in tumor microenvironment

LTF danger signal response pathway

Acute viral myocarditis

T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection

TLR4 signaling and tolerance

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

NAD metabolism, sirtuins and aging

PDGF pathway

Folate metabolism

Vitamin B12 metabolism

Copper metabolism

Type II interferon signaling

Glycolysis and gluconeogenesis

Nucleotide GPCRs

FAS pathway and stress induction of HSP regulation

Methionine de novo and salvage pathway

Selenium micronutrient network

Folate metabolism

Zinc homeostasis

Hair follicle development: cytodifferentiation - part 3 of 3

Acetogenesis

Tryptophan degradation via kynurenine

miRNA degrading enzymes

miRNA targets in ECM and membrane receptors

IL1 and megakaryocytes in obesity

Pluripotent stem cell differentiation pathway

Spinal cord injury

Allograft rejection

Microglia pathogen phagocytosis pathway

Regulation of actin cytoskeleton

HIPK2 in kidney fibrosis

Biogenic amine synthesis

ABA biosynthesis

DNA IR-damage and cellular response via ATR

4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression

TGF-beta signaling pathway

TNF-alpha signaling pathway

Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex

Immune response to tuberculosis

miR-222 in exercise-induced cardiac growth

Angiopoietin-like protein 8 regulatory pathway

Melatonin metabolism and effects

Aryl hydrocarbon receptor pathway

Ebola virus infection in host

SARS-CoV-2 and ACE2 receptor: molecular mechanisms

STING pathway in Kawasaki-like disease and COVID-19

Airway smooth muscle cell contraction

Serotonin and anxiety-related events

ERK pathway in Huntington's disease

BDNF pathway

Insulin signaling

RAC1/PAK1/p38/MMP2 pathway

Acetylcholine synthesis

Ferroptosis

Photodynamic therapy-induced AP-1 survival signaling

Cholesterol biosynthesis pathway

MAPK signaling pathway

Salmonella virulence regulatory network

Arginine biosynthesis

Fibrin complement receptor 3 signaling pathway

Serine metabolism

MTHFR deficiency

Vitamin B12 disorders

Long-day flowering time pathway

Cell differentiation - index

Focal adhesion: PI3K-Akt-mTOR-signaling pathway

Burn wound healing

Mecp2 and associated Rett syndrome

Statin inhibition of cholesterol production

Development of pulmonary dendritic cells and macrophage subsets

Beta-oxidation of unsaturated fatty acids

Effect of L-carnitine on metabolism

Parkin-ubiquitin proteasomal system pathway

Vitamin D receptor pathway

Nanoparticle triggered regulated necrosis

Vasopressin-regulated water reabsorption

Homologous recombination

Burn Wound Healing

Nicotine metabolism in liver cells

Alzheimer's disease

Alzheimer's disease and miRNA effects

Gut-liver indole metabolism

Tryptophan metabolism

Major receptors targeted by epinephrine and norepinephrine

Metabolism of alpha-linolenic acid

Blood clotting and drug effects

Role of carnosine in muscle contraction

Hereditary leiomyomatosis and renal cell carcinoma pathway

GABA receptor signaling

Host-pathogen interaction of human coronaviruses - MAPK signaling

Melanoma

Oligodendrocyte specification and differentiation, leading to myelin components for CNS

Oxidation by cytochrome P450

Wnt signaling pathway and pluripotency

One-carbon metabolism and related pathways

Chemokine signaling pathway

Primary focal segmental glomerulosclerosis (FSGS)

Arrhythmogenic right ventricular cardiomyopathy

HIF1A and PPARG regulation of glycolysis

Ketogenesis and ketolysis

Urea cycle and metabolism of amino groups

Steroid biosynthesis

DDX1 as a regulatory component of the Drosha microprocessor

TCA cycle (aka Krebs or citric acid cycle)

Hypoxia-dependent proliferation of myoblasts

NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence

NAD+ metabolism

Endoplasmic reticulum stress response in coronavirus infection

Beta-oxidation meta-pathway

NAD+ biosynthetic pathways

miR-222 in exercise-induced cardiac growth

Fatty acid beta-oxidation meta-pathway

Soluble ACE2-mediated cell entry of SARS-CoV-2

Development and heterogeneity of the ILC family

Wnt signaling in kidney disease

Hepatocyte growth factor receptor signaling

Intracellular auxin transport

Polar auxin transport

Wnt signaling pathway

Metabolic reprogramming in colon cancer

Glucosinolate biosynthesis from branched-chain amino acid

Glucosinolate biosynthesis from methionine

Ketone bodies synthesis and degradation

Nodal signaling pathway

BMP signaling pathway

Glycolysis and Gluconeogenesis

Eukaryotic transcription initiation

Homologous recombination

Mismatch repair

Vulval development and SynMuv

Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway

ERK1-ERK2 MAPK cascade

DNA IR-double strand breaks and cellular response via ATM

Leptin-insulin signaling overlap

Striated muscle contraction pathway

Lung fibrosis

Flavonoid pathway

Mesodermal commitment pathway

Apoptosis

Histone modifications

Pathogenic Escherichia coli infection

Glioblastoma signaling pathways

SREBF and miR33 in cholesterol and lipid homeostasis

Eukaryotic transcription initiation

Heart development

miRNAs involved in DNA damage response

Angiogenesis

Vitamin D metabolism

FGF signaling pathway

Vulval development

Sphingolipid pathway

Cell division: first embryonic mitosis

Monoamine GPCRs

Phase I biotransformations, non P450

Cholesterol biosynthesis

Homologous recombination

Programmed cell death

Regulation of Wnt / B-catenin signaling by small molecule compounds

Crystal toxin triggered necrosis pathway

FAS pathway and stress induction of HSP regulation

Signal transduction of S1P receptor

Eukaryotic transcription initiation

Calcium regulation in cardiac cells

Steroid biosynthesis

Exercise-induced circadian regulation

Mapk signaling pathway

Alpha 6 beta 4 integrin signaling pathway

Inflammatory response pathway

GPCRs, class B secretin-like

Osteoclast signaling

IL-2 signaling pathway

Matrix metalloproteinases

PDGFR-alpha and STMN1 cooperate to exacerbate cytotoxic effects of vinblastine

GPCRs, other

Mitochondrial long chain fatty acid beta-oxidation

IL-6 signaling pathway

Robo4 and VEGF signaling pathways crosstalk

BMP signaling pathway in eyelid development

Interleukin-1 induced activation of NF-kB

GPCRs, small ligand

GPCRs, class C metabotropic glutamate, pheromone

Eicosanoid synthesis

IL-17 signaling pathway

Translation factors

Electron transport chain

Interleukin-1 (IL-1) structural pathway

Wnt signaling

IL-17 signaling pathway

Neural crest differentiation

Complement activation, classical pathway

GPCRs, class A rhodopsin-like

Apoptosis modulation by HSP70

IL-5 signaling pathway

GPCRs, odorant

GPCRs, non-odorant

Mitochondrial gene expression

Selenium metabolism / selenoproteins

Methylation pathways

Catalytic cycle of mammalian flavin-containing monooxygenases (FMOs)

DNA mismatch repair

GPCRs, class C metabotropic glutamate, pheromone

DNA repair pathways, full network

Direct reversal repair

Cholesterol biosynthesis with skeletal dysplasias

MED and pseudoachondroplasia genes

Autosomal recessive osteopetrosis pathways

Type I collagen synthesis in the context of osteogenesis imperfecta

GPCRs, class A rhodopsin-like

NO/cGMP/PKG mediated neuroprotection

OSX and miRNAs in tooth development

Robo4 and VEGF signaling pathways crosstalk

Embryonic stem cell pluripotency pathways

BMP signaling in eyelid development

Mitochondrial gene expression

ATM signaling in development and disease

MYD88 distinct input-output pathway

ATR signaling

TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition

Toll-like receptor signaling related to MyD88

Physico-chemical features and toxicity-associated pathways

Cell-type dependent selectivity of CCK2R signaling

Amplification and expansion of oncogenic pathways as metastatic traits

lncRNA-mediated mechanisms of therapeutic resistance

Interactions between LOXL4 and oxidative stress pathway

Hypothesized pathways in pathogenesis of cardiovascular disease

Metabolism of dichloroethylene by CYP450

Circadian rhythm genes

MicroRNA for targeting cancer growth and vascularization in glioblastoma

G protein signaling pathways

GPCRs, class B secretin-like

Hypoxia-mediated EMT and stemness

Estrogen receptor pathway

Glucocorticoid receptor pathway

Constitutive androstane receptor pathway

Hair follicle development: organogenesis - part 2 of 3

Felbamate metabolism

Cardiac hypertrophic response

TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc)

Gastric cancer network 2

Gastric cancer network 1

Endothelin pathways

Fatty acid omega-oxidation

Cell differentiation - expanded index

SRF and miRs in smooth muscle differentiation and proliferation

Matrix metalloproteinases

GPCRs, other

Nuclear receptors in lipid metabolism and toxicity

Small ligand GPCRs

Ketone bodies synthesis and degradation

Exercise-induced circadian regulation

TSLP signaling pathway

Isoprenoid precursor biosynthesis in Pf apicoplasts

IGF-1 signaling

Growth hormone receptor (GHR) signaling

Osteoblast signaling

Ganglio sphingolipid metabolism

Ketone bodies synthesis and degradation

Complement and coagulation cascades

Inflammatory response pathway

Acetylcholine synthesis

ACE inhibitor pathway

Ketone bodies synthesis and degradation

Pentose phosphate pathway 2

De novo NAD biosynthesis

Tyrosine biosynthesis

Glycolysis and gluconeogenesis

MAPK signaling pathway

Phosphatidic acid and phospholipid biosynthesis

Cell cycle and cell division

Sphingolipid metabolism

Allantoin degradation

TCA cycle - detailed

Polyamine biosynthesis

Phenylalanine, tyrosine, and tryptophan biosynthesis

Glutathione biosynthesis

Phenylalanine biosynthesis

Tryptophan biosynthesis

Aspartate biosynthesis

Cholesterol biosynthesis

DNA replication

Principal pathways of carbon metabolism

Regulation of actin cytoskeleton

mRNA processing

MAPK signaling pathway

Mitochondrial long chain fatty acid beta-oxidation

Glucose sensing and signaling

Toll, IMD, JAK/STAT pathways for immune response to pathogens

Genetic interactions between sugar and hormone signaling

Calcium regulation in cardiac cells

FAS pathway and stress induction of HSP regulation

Ketone bodies synthesis and degradation

Polyol pathway

Lipid metabolism pathway

GPR40 pathway

Imatinib and chronic myeloid leukemia

Ketone bodies synthesis and degradation

Hematopoietic stem cell differentiation

T cell receptor and co-stimulatory signaling

NAD biosynthesis II (from tryptophan)

miRNA biogenesis

Synaptic vesicle pathway

Neural crest differentiation

Microtubule cytoskeleton regulation

EPO receptor signaling

G13 signaling pathway

Endochondral ossification

DNA replication

Exercise-induced circadian regulation

Wnt signaling pathway

Apoptosis modulation by HSP70

FAS pathway and stress induction of HSP regulation

Cardiovascular signaling

ACE inhibitor pathway

Complement and coagulation cascades

Translation factors

mRNA processing

Mitochondrial unfolded-protein response

Notch signaling pathway

Biosynthesis of aldosterone and cortisol

Hedgehog signaling pathway

Osteoclast

Apoptosis modulation by HSP70

Cytoplasmic ribosomal proteins

Oxidative damage response

Amino acid metabolism

Thick ascending limb transporters

Proximal tubule transporters

Toll, IMD, JAK/STAT pathways for immune response to pathogens

Humoral immune response to fungal and bacterial pathogens

Acetylcholine synthesis

Regulation of actin cytoskeleton

Synthesis and degradation of ketone bodies

TCA cycle

mir219 in oligodendrocyte differentiation and myelination

Proteasome degradation

Matrix metalloproteinases

Notch signaling pathway

Focal adhesion

Proteasome degradation

Cytoplasmic ribosomal proteins

Small ligand GPCRs

Statin pathway

Mitochondrial gene expression

Homologous recombination

FAS pathway and stress induction of HSP regulation

Apoptosis modulation by HSP70

Synthesis and degradation of ketone bodies

PPAR signaling pathway

Non-canonical Wnt pathway

MAPK signaling pathway

p38 MAPK signaling pathway

MAPK signaling pathway

p38 MAPK signaling pathway

Monoamine transport

Exercise-induced circadian regulation

Synthesis and degradation of ketone bodies

ACE inhibitor pathway

Inflammatory response pathway

Insulin signaling

ACE inhibitor pathway

BDNF-TrkB signaling

Microglia pathogen phagocytosis pathway

MAPK signaling pathway

Cytoplasmic ribosomal proteins

G13 signaling pathway

p38 Mapk signaling pathway

Common pathways underlying drug addiction

ATM signaling pathway

Cytokines and inflammatory response

Acetylcholine synthesis

Insulin signaling

p38 MAPK signaling pathway

MAPK signaling pathway

Ectoderm differentiation

Focal adhesion

Insulin signaling

MAPK cascade

Novel Jun-Dmp1 pathway

Hepatitis C and hepatocellular carcinoma

p38 Mapk signaling pathway

ESC pluripotency pathways

Focal adhesion: PI3K-Akt-mTOR signaling pathway

FOXA2 pathway

Bile acids synthesis and enterohepatic circulation

Wnt signaling in kidney disease

TYROBP causal network in microglia

Regulation of apoptosis by parathyroid hormone-related protein

Renin-angiotensin system

Wnt/beta-catenin signaling pathway in leukemia

Insulin signaling in adipocytes (diabetic condition)

Insulin signaling in adipocytes (normal condition)

Tyrobp causal network in microglia

NOTCH1 regulation of endothelial cell calcification

Ebstein-Barr virus LMP1 signaling

Irinotecan pathway

Host-pathogen interaction of human coronaviruses - autophagy

Aspirin and miRNAs

One-carbon metabolism

Trans-sulfuration, one-carbon metabolism and related pathways

Retinoblastoma gene in cancer

One-carbon metabolism and related pathways

Toll-like receptor signaling

Lactose degradation and galactose metabolism

FGF23 signaling in hypophosphatemic rickets and related disorders

PI3K/AKT/mTOR - vitamin D3 signaling

EDA signaling in hair follicle development

Nanomaterial-induced inflammasome activation

BMP2-WNT4-FOXO1 pathway in primary endometrial stromal cell differentiation

Canonical and non-canonical TGF-B signaling

Dysregulated miRNA targeting in insulin/PI3K-AKT signaling

MAPK and NFkB signaling pathways inhibited by Yersinia YopJ

Canonical and non-canonical Notch signaling

Phytochrome signaling pathway to turn on photomorphogenesis

Equilibrium signaling pathway of differentiated cells

EDA signaling in hair follicle development

Pathways affected in adenoid cystic carcinoma

Wnt myofibroblastic activation of hepatic stellate cells

Farnesoid X receptor pathway

PPAR-alpha pathway

Liver X receptor pathway

Endoderm differentiation

Alzheimer's disease

Sterol regulatory element-binding proteins (SREBP) signaling

Nuclear receptors

Peptidoglycan cytoplasmic synthesis and recycling pathways

Modulators of TCR signaling and T cell activation

Wnt Signaling Pathway and Pluripotency

Alanine and aspartate metabolism

Monoamine GPCRs

Histidine metabolism

Cholesterol metabolism

Lung fibrosis

Estrogen signaling

Amyotrophic lateral sclerosis (ALS)

Galanin receptor pathway

Synaptic signaling pathways associated with autism spectrum disorder

Intracellular trafficking proteins involved in CMT neuropathy

p53 transcriptional gene network

Pilocytic astrocytoma

Somitogenesis in the context of spondylocostal dysostosis

Proteoglycan biosynthesis

Splicing factor NOVA regulated synaptic proteins

Acetate mediated promotion of metabolic syndrome

Nanoparticle-mediated activation of receptor signaling

Nanomaterial induced apoptosis

Glycosaminoglycan degradation

Ciliopathies

Nuclear receptors in lipid metabolism and toxicity

Nuclear receptors in lipid metabolism and toxicity

Ptf1a related regulatory pathway

mBDNF and proBDNF regulation of GABA neurotransmission

PKC-gamma calcium signaling pathway in ataxia

Influenza A virus infection

Tumor suppressor activity of SMARCB1

Hexoses metabolism in proximal tubules

Lipids measured in liver metastasis from breast cancer

Cancer immunotherapy by CTLA4 blockade

MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement

FABP4 in ovarian cancer

Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors

ncRNAs involved in STAT3 signaling in hepatocellular carcinoma

Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer

miRNA regulation of p53 pathway in prostate cancer

miRNA regulation of prostate cancer signaling pathways

mir-193a and MVP in colon cancer metastasis

miR-509-3p alteration of YAP1/ECM axis

RIOK1 and RIOK2 in EGFR- and PI3K-mediated tumorigenesis

Apoptosis-related network due to altered Notch3 in ovarian cancer

Overview of interferons-mediated signaling pathway

Relationship between inflammation, COX-2 and EGFR

Macrophage markers

Cell migration and invasion through p75NTR

Metastatic brain tumor

Control of immune tolerance by vasoactive intestinal peptide

Monoamine GPCRs

Amino acid conjugation

Estrogen metabolism

p53 signal pathway

Oxidative phosphorylation

Monoamine GPCRs

Nuclear receptors in lipid metabolism and toxicity

Leptin and adiponectin

Angiotensin II signaling (acute) in thick ascending limbs

Valproic acid pathway

Turbo design of glycolysis

Initiation of transcription and translation elongation at the HIV-1 LTR

EV release from cardiac cells and their functional effects

Alanine and aspartate metabolism

Monoamine GPCRs

Lidocaine metabolism

Dopamine metabolism

PPAR signaling pathway

Serotonin and anxiety-related events

Nucleotide GPCRs

Glutathione metabolism

Nuclear receptors in lipid metabolism and toxicity

Nuclear receptors in lipid metabolism and toxicity

Estrogen metabolism

Aflatoxin B1 metabolism

Estrogen signaling

Estrogen metabolism

Aflatoxin B1 metabolism

Nuclear receptors in lipid metabolism and toxicity

Glutathione metabolism

Metapathway biotransformation Phase I and II

NRF2 pathway

Iron metabolism in placenta

Photodynamic therapy-induced NF-kB survival signaling

Photodynamic therapy-induced HIF-1 survival signaling

Photodynamic therapy-induced unfolded protein response

Type 2 papillary renal cell carcinoma

PPAR signaling pathway

Novel intracellular components of RIG-I-like receptor pathway

exRNA mechanism of action and biogenesis

Serotonin and anxiety

H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity

Extracellular vesicle-mediated signaling in recipient cells

Gene regulatory network modelling somitogenesis

Copper homeostasis

Caloric restriction and aging

Benzo(a)pyrene metabolism

ApoE and miR-146 in inflammation and atherosclerosis

Monoamine GPCRs

Retinol metabolism

Arylamine metabolism

Vitamins A and D - action mechanisms

Thermogenesis

mRNA, protein, and metabolite inducation pathway by cyclosporin A

Tryptophan metabolism

Adipogenesis

daf-2 or insulin signaling pathway

Polyol pathway

Polyol pathway

Monoamine GPCRs

Tryptophan metabolism

Amino acid conjugation of benzoic acid

Somatroph axis (GH) and its relationship to dietary restriction and aging

Transcription factor regulation in adipogenesis

miR-517 relationship with ARCN1 and USP1

Type III interferon signaling

Genes targeted by miRNAs in adipocytes

Extracellular vesicles in the crosstalk of cardiac cells

Glucosinolate biosynthesis (from aromatic amino acid)

Cytosolic DNA-sensing pathway

Glutathione metabolism

Mismatch repair

Tryptophan metabolism

Tryptophan metabolism

Interactome of polycomb repressive complex 2 (PRC2)

Interactions between immune cells and microRNAs in tumor microenvironment

FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma

Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)

Mammary gland development pathway - Involution (Stage 4 of 4)

Mammary gland development pathway - Puberty (Stage 2 of 4)

Mammary gland development pathway - Embryonic development (Stage 1 of 4)

Dual hijack model of Vif in HIV infection

Ciliary landscape

Circulating monocytes and cardiac macrophages in diastolic dysfunction

MicroRNA network associated with chronic lymphocytic leukemia

Platelet-mediated interactions with vascular and circulating cells

Adipogenesis

Serotonin and anxiety

Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells

Glyoxylate cycle

Chemokine signaling pathway

Glutamate degradation III

Homologous recombination

Heterochronic gene regulation of development

G1 to S cell cycle control

Cell engulfment

Hfe effect on hepcidin production

G1 to S cell cycle control

mRNA Processing

G1 to S cell cycle control

Apoptosis

G1 to S cell cycle control

Apoptosis

Apoptosis

G1 to S cell cycle control

G1 to S cell cycle control

mRNA Processing

Apoptosis

Vitamin B9 (folate) biosynthesis pathway

Metapathway biotransformation

ApoE and miR-146 in inflammation and atherosclerosis

Model of Fgf and Wnt crosstalk in tailbud

Glycine biosynthesis

miR-127 in mesendoderm differentiation

Hfe effect on hepcidin production

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

p53 pathway

Nuclear Receptors

mir-124 predicted interactions with cell cycle and differentiation

Sulfate assimilation pathway II

let-7 inhibition of ES cell reprogramming

eIF5A regulation in response to inhibition of the nuclear export system

Gene regulatory network modelling somitogenesis

Metapathway biotransformation

Adipogenesis

G1 to S cell cycle control

Adipogenesis

Mismatch repair

Metapathway biotransformation

Neural crest development

RNA interference and miRNA

Type II interferon signaling (IFNG)

Homologous recombination

Mismatch repair

miR-1 in cardiac development

Mismatch repair

Homologous recombination

Mismatch repair

Mismatch repair