Adipogenesis (WP987)

Bos taurus

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.

Authors

Kristina Hanspers and Martina Summer-Kutmon

Activity

last edited

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Cited In

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Organisms

Bos taurus

Communities

Annotations

Pathway Ontology

signaling pathway pertinent to development

Participants

Label Type Compact URI Comment
IGF-I GeneProduct ensembl:ENSBTAG00000011082 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3479
PTGIS GeneProduct ensembl:ENSBTAG00000017537 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5740
PPARD GeneProduct ensembl:ENSBTAG00000017542 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5467
CREB1 GeneProduct ensembl:ENSBTAG00000005474 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1385
MIXL1 GeneProduct ensembl:ENSBTAG00000002139 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:83881
ID3 GeneProduct ensembl:ENSBTAG00000030425 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3399
WNT10B GeneProduct ensembl:ENSBTAG00000015347 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7480
STAT5A GeneProduct ensembl:ENSBTAG00000009496 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6776
STAT5B GeneProduct ensembl:ENSBTAG00000010125 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6777
DLK GeneProduct ensembl:ENSBTAG00000037899 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8788
GR-A GeneProduct ensembl:ENSBTAG00000019472 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2908
DDIT3 GeneProduct ensembl:ENSBTAG00000031544 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1649
LIF GeneProduct ensembl:ENSBTAG00000007424 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3976
CYP26A1 GeneProduct ensembl:ENSBTAG00000021118 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1592
CYP26B1 GeneProduct ensembl:ENSBTAG00000012212 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:56603
RXRA GeneProduct ensembl:ENSBTAG00000017851 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6256
RARA GeneProduct ensembl:ENSBTAG00000012500 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5914
NR1H3 GeneProduct ensembl:ENSBTAG00000010681 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10062
LPL GeneProduct ensembl:ENSBTAG00000012855 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4023
SREBF1 GeneProduct ensembl:ENSBTAG00000007884 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6720
FAS GeneProduct ensembl:ENSBTAG00000010785 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:355
RBL1 GeneProduct ensembl:ENSBTAG00000011541 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5933
GATA3 GeneProduct ensembl:ENSBTAG00000017243 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2625
GATA2 GeneProduct ensembl:ENSBTAG00000019707 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2624
PPARG GeneProduct ensembl:ENSBTAG00000001333 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5468
MEF2A GeneProduct ensembl:ENSBTAG00000010649 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4205
MEF2C GeneProduct ensembl:ENSBTAG00000020701 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4208
MEF2D GeneProduct ensembl:ENSBTAG00000046545 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4209
ASIP GeneProduct ensembl:ENSBTAG00000034077 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:434
TNF GeneProduct ensembl:ENSBTAG00000025471 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7124
MIF GeneProduct ensembl:ENSBTAG00000007375 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4282
TGFB1 GeneProduct ensembl:ENSBTAG00000020457 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7040
SERPINE1 GeneProduct ensembl:ENSBTAG00000014465 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5054
SLC2A4 GeneProduct ensembl:ENSBTAG00000009190 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6517
SCD GeneProduct ensembl:ENSBTAG00000047957 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6319
TWIST1 GeneProduct ensembl:ENSBTAG00000046922 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7291
OB GeneProduct ensembl:ENSBTAG00000014911 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3952
RETN GeneProduct ensembl:ENSBTAG00000004716 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:56729
DF GeneProduct ensembl:ENSBTAG00000046245 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1675
GTF3A GeneProduct ensembl:ENSBTAG00000012600 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2971
RB1 GeneProduct ensembl:ENSBTAG00000006640 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5925
RBL2 GeneProduct ensembl:ENSBTAG00000016243 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5934
ADIPOQ GeneProduct ensembl:ENSBTAG00000019813 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9370
PLIN2 GeneProduct ensembl:ENSBTAG00000005718 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:123
AGT GeneProduct ensembl:ENSBTAG00000012393 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:183
CDKN1A GeneProduct ensembl:ENSBTAG00000008353 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1026
E2F1 GeneProduct ensembl:ENSBTAG00000003971 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1869
SP1 GeneProduct ensembl:ENSBTAG00000003021 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6667
HMGA1 GeneProduct ensembl:ENSBTAG00000034529 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3159
PLIN GeneProduct ensembl:ENSBTAG00000015350 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5346
IL6 GeneProduct ensembl:ENSBTAG00000014921 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3569
GADD45A GeneProduct ensembl:ENSBTAG00000013860 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1647
GADD45B GeneProduct ensembl:ENSBTAG00000025462 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4616
BMP1 GeneProduct ensembl:ENSBTAG00000000917 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:649
BMP2 GeneProduct ensembl:ENSBTAG00000005111 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:650
BMP3 GeneProduct ensembl:ENSBTAG00000017642 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:651
BMP4 GeneProduct ensembl:ENSBTAG00000003835 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:652
NDN GeneProduct ensembl:ENSBTAG00000002186 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4692
FOXO1 GeneProduct ensembl:ENSBTAG00000044105 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2308
KLF5 GeneProduct ensembl:ENSBTAG00000002129 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:688
FOXC2 GeneProduct ensembl:ENSBTAG00000012465 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2303
PPARGC1A GeneProduct ensembl:ENSBTAG00000017024 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10891
NCOA1 GeneProduct ensembl:ENSBTAG00000015007 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8648
NCOA2 GeneProduct ensembl:ENSBTAG00000020312 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10499
PPARA GeneProduct ensembl:ENSBTAG00000008063 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5465
STAT3 GeneProduct ensembl:ENSBTAG00000021523 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6774
STAT2 GeneProduct ensembl:ENSBTAG00000004380 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6773
STAT1 GeneProduct ensembl:ENSBTAG00000007867 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6772
STAT6 GeneProduct ensembl:ENSBTAG00000006335 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6778
SOCS1 GeneProduct ensembl:ENSBTAG00000004386 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8651
SOCS3 GeneProduct ensembl:ENSBTAG00000008441 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9021
CNTFR GeneProduct ensembl:ENSBTAG00000015361 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1271
LIFR GeneProduct ensembl:ENSBTAG00000010423 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3977
IL6ST GeneProduct ensembl:ENSBTAG00000017745 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3572
MBNL1 GeneProduct ensembl:ENSBTAG00000004564 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4154
OSM GeneProduct ensembl:ENSBTAG00000016163 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5008
CTNNB1 GeneProduct ensembl:ENSBTAG00000016420 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1499
UCP1 GeneProduct ensembl:ENSBTAG00000004647 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7350
WNT5B GeneProduct ensembl:ENSBTAG00000001341 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:81029
WNT1 GeneProduct ensembl:ENSBTAG00000015364 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7471
SMAD3 GeneProduct ensembl:ENSBTAG00000012599 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4088
FZD1 GeneProduct ensembl:ENSBTAG00000002107 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8321
DVL1 GeneProduct ensembl:ENSBTAG00000010696 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1855
HNF1A GeneProduct ensembl:ENSBTAG00000021795 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6927
RXRG GeneProduct ensembl:ENSBTAG00000016801 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6258
FRZB GeneProduct ensembl:ENSBTAG00000010977 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2487
NAMPT GeneProduct ensembl:ENSBTAG00000015509 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10135
SPOCK1 GeneProduct ensembl:ENSBTAG00000003502 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6695
TRIB3 GeneProduct ensembl:ENSBTAG00000017007 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:57761
GATA4 GeneProduct ensembl:ENSBTAG00000005425 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2626
NR2F1 GeneProduct ensembl:ENSBTAG00000017599 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7025
NRIP1 GeneProduct ensembl:ENSBTAG00000047293 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8204
RORA GeneProduct ensembl:ENSBTAG00000015904 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6095
PRLR GeneProduct ensembl:ENSBTAG00000025035 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5618
ADPN GeneProduct ensembl:ENSBTAG00000045746 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:80339
CUGBP1 GeneProduct ensembl:ENSBTAG00000002520 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10658
HIF1A GeneProduct ensembl:ENSBTAG00000020935 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3091
KLF6 GeneProduct ensembl:ENSBTAG00000015188 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1316
KLF7 GeneProduct ensembl:ENSBTAG00000044097 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8609
SFRP4 GeneProduct ensembl:ENSBTAG00000015366 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6424
NCOR1 GeneProduct ensembl:ENSBTAG00000013271 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9611
NCOR2 GeneProduct ensembl:ENSBTAG00000024603 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9612
KLF15 GeneProduct ensembl:ENSBTAG00000008313 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:28999
EGR2 GeneProduct ensembl:ENSBTAG00000046409 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1959
EBF1 GeneProduct ensembl:ENSBTAG00000037508 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1879
EPAS1 GeneProduct ensembl:ENSBTAG00000003711 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2034
AHR GeneProduct ensembl:ENSBTAG00000007746 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:196
CISD1 GeneProduct ensembl:ENSBTAG00000003634 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:55847
WWTR1 GeneProduct ensembl:ENSBTAG00000007814 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:25937
GDF10 GeneProduct ensembl:ENSBTAG00000001019 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2662
IRS1 GeneProduct ensembl:ENSBTAG00000021308 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3667
IRS4 GeneProduct ensembl:ENSBTAG00000006535 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8471
BSCL2 GeneProduct ensembl:ENSBTAG00000002503 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26580
LMNA GeneProduct ensembl:ENSBTAG00000017574 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4000
AGPAT2 GeneProduct ensembl:ENSBTAG00000025161 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10555
ZMPSTE24 GeneProduct ensembl:ENSBTAG00000044178 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:10269
LPIN1 GeneProduct ensembl:ENSBTAG00000007689 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23175
LPIN2 GeneProduct ensembl:ENSBTAG00000012060 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9663
HSL GeneProduct ensembl:ENSBTAG00000038321 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3991
PCK1 GeneProduct ensembl:ENSBTAG00000001936 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5105
PCK2 GeneProduct ensembl:ENSBTAG00000011934 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5106
IRS2 GeneProduct ensembl:ENSBTAG00000012019 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8660
LPIN3 GeneProduct ensembl:ENSBTAG00000009165 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:64900
E2F4 GeneProduct ensembl:ENSBTAG00000012063 HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1874

References

  1. Molecular regulation of adipogenesis. Rosen ED, Spiegelman BM. Annu Rev Cell Dev Biol. 2000;16:145–71. PubMed Europe PMC Scholia