Iron homeostasis (WP1596)

Mus musculus

Iron is nessisary for all mammalian cells but is also toxic in excess. This pathway shows the regulation of iron between a cell and the blood stream.


Martijn Van Iersel , Kristina Hanspers , Samuel Sklar , Egon Willighagen , Daniela Digles , Martina Summer-Kutmon , and Eric Weitz


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Mus musculus



Pathway Ontology

iron homeostasis pathway


Label Type Compact URI Comment
Iron Metabolite hmdb:HMDB0000692
Iron Metabolite hmdb:HMDB0000692
Transferrin GeneProduct ensembl:ENSMUSG00000032554
Fth1 GeneProduct ncbigene:14319
Trfr2 GeneProduct ensembl:ENSMUSG00000029716
Ftl1 GeneProduct ensembl:ENSMUSG00000050708
hepcidin-2 GeneProduct ensembl:ENSMUSG00000056978
Ireb2 GeneProduct ensembl:ENSMUSG00000032293
hepcidin GeneProduct ensembl:ENSMUSG00000050440
Tnf GeneProduct ensembl:ENSMUSG00000024401
IL-6 GeneProduct ensembl:ENSMUSG00000025746
hemojuvelin GeneProduct ensembl:ENSMUSG00000038403
Hfe GeneProduct ensembl:ENSMUSG00000006611
IL6R GeneProduct ensembl:ENSMUSG00000027947
hepcidin-2 GeneProduct ensembl:ENSMUSG00000056978
hepcidin GeneProduct ensembl:ENSMUSG00000050440
Ferroportin GeneProduct ensembl:ENSMUSG00000025993
IL-1 GeneProduct ensembl:ENSMUSG00000027399