Oxidation by cytochrome P450 (WP43)

Homo sapiens

Authors

Arik , Martijn Van Iersel , Thomas Kelder , Chris Evelo , Susan Coort , Mohhafez , Christine Chichester , Egon Willighagen , Kristina Hanspers , Zahra Roudbari , Martina Summer-Kutmon , Zhangx888 , Eric Weitz , and Finterly Hu

Activity

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Cited In

• Identifying Drug-Induced Liver Injury Associated With Inflammation-Drug and Drug-Drug Interactions in Pharmacologic Treatments for COVID-19 by Bioinformatics and System Biology Analyses: The Role of Pregnane X Receptor (2022).
• Genomic footprints of dryland stress adaptation in Egyptian fat-tail sheep and their divergence from East African and western Asia cohorts (2017).
• Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation (2023).

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Organisms

Homo sapiens

Communities

ONTOX

Annotations

Pathway Ontology

phase I biotransformation pathway via cytochrome P450 xenobiotics biodegradation pathway

Cell Type Ontology

hepatocyte

References

1. Toxicology [Internet]. Niesink R, Hollinger MA, De Vries J. CRC Press; 1996. 1312 p. Available from: https://books.google.com/books/about/Toxicology.html?hl=&id=mwN9QgAACAAJ OpenLibrary Worldcat