Oxidation by cytochrome P450 (WP43)
Homo sapiens
Oxidation of a substrate by Cytochrome P450. Adapted from Niesink et al., Chapter 3, p. 47-48. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP43 CPTAC Assay Portal]
Authors
Arik , Martijn Van Iersel , Thomas Kelder , Chris Evelo , Susan Coort , Mohhafez , Christine Chichester , Egon Willighagen , Kristina Hanspers , Zahra Roudbari , Martina Summer-Kutmon , Zhangx888 , Eric Weitz , and Finterly HuActivity
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Cited By
- Identifying Drug-Induced Liver Injury Associated With Inflammation-Drug and Drug-Drug Interactions in Pharmacologic Treatments for COVID-19 by Bioinformatics and System Biology Analyses: The Role of Pregnane X Receptor (2022).
- Genomic footprints of dryland stress adaptation in Egyptian fat-tail sheep and their divergence from East African and western Asia cohorts (2017).
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Organisms
Homo sapiensCommunities
Annotations
Pathway Ontology
phase I biotransformation pathway via cytochrome P450 xenobiotics biodegradation pathwayCell Type Ontology
hepatocyteReferences
- Hollinger MA, Niesink R, De Vries J. Toxicology [Internet]. Boca Raton, FL: CRC Press; 1996. 1284 p. Available from: https://openlibrary.org/books/OL791209M/Toxicology OpenLibrary Worldcat