Signal transduction of S1P receptor (WP57)
Mus musculus
This is a representation of figure 2 from T. Hla, et al. 2001, Science, 294, pg. 1877. Sphingosine-1-phosphate (S1P) is a signaling sphingolipid, also known as lysosphingolipid. It is also referred to as a bioactive lipid mediator. Sphingolipids at large form a class of lipids characterized by a particular aliphatic aminoalcohol, which is sphingosine.
Authors
Scott Doniger , Daniela Digles , Kristina Hanspers , and Eric WeitzActivity
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Cited In
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Organisms
Mus musculusCommunities
Annotations
Pathway Ontology
sphingosine 1-phosphate signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Mapk3 | GeneProduct | ncbigene:26417 | |
| Pik3c2g | GeneProduct | ncbigene:18705 | |
| Edg3 | GeneProduct | ncbigene:13610 | |
| Mapk1 | GeneProduct | ncbigene:26413 | |
| Racgap1 | GeneProduct | ncbigene:26934 | |
| Edg1 | GeneProduct | ncbigene:13609 | |
| Sphk1 | GeneProduct | ncbigene:20698 | |
| Gnai1 | GeneProduct | ncbigene:14677 | |
| Mapk7 | GeneProduct | ncbigene:23939 | |
| Plcb3 | GeneProduct | ncbigene:18797 | |
| Akt2 | GeneProduct | ncbigene:11652 | |
| Asah2 | GeneProduct | ncbigene:54447 | |
| Smpd2 | GeneProduct | ncbigene:20598 | |
| Gnai2 | GeneProduct | ncbigene:14678 | |
| Edg8 | GeneProduct | ncbigene:94226 | |
| Mapk12 | GeneProduct | ncbigene:29857 | |
| Akt3 | GeneProduct | ncbigene:23797 | |
| Akt1 | GeneProduct | ncbigene:11651 | |
| Mapk6 | GeneProduct | ncbigene:50772 | |
| Sphk2 | GeneProduct | ncbigene:56632 | |
| Gnai3 | GeneProduct | ncbigene:14679 | |
| Edg5 | GeneProduct | ncbigene:14739 |