Glucose sensing and signaling (WP3860)
Arabidopsis thaliana
This pathway is modeled after Figure 1 in the Article "Sugar Sensing and Signaling" (See Bibliography). The discovery of several new molecules such as HXK1 and KIN10/11 have impacted the sugar regulation within a Arabidopsis therefore the figure above describes our insight into the sugar sensing and signaling network, and several of the molecular mechanisms that are included. Energy deprivation leads to mobilization of starch stored in chlorophyll to provide energy for the cell. Gene expression of proteins involved in energy regulation for the cell is also altered.
Authors
AAR&Co , Martina Summer-Kutmon , Kristina Hanspers , and Eric WeitzActivity
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Organisms
Arabidopsis thalianaCommunities
Annotations
Pathway Ontology
signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Trehalose | Metabolite | hmdb:HMDB0000975 | |
| T6P | Metabolite | hmdb:HMDB0001124 | |
| Sucrose | Metabolite | hmdb:HMDB0000258 | |
| G6P | Metabolite | pubchem.compound:208 | |
| Triosephosphate | Metabolite | pubchem.compound:729 | |
| UDP-Glucose | Metabolite | pubchem.compound:8629 | |
| TPP | Metabolite | chebi:9532 | |
| D-Glucose | Metabolite | hmdb:HMDB0000122 | |
| Maltose | Metabolite | hmdb:HMDB0000163 | |
| Fructose | Metabolite | hmdb:HMDB0000660 | |
| Glucose | Metabolite | hmdb:HMDB0000122 | |
| G6P | Metabolite | pubchem.compound:208 | |
| Glucose | Metabolite | hmdb:HMDB0000122 | |
| Fructose | Metabolite | hmdb:HMDB0000660 | |
| Glucose | Metabolite | hmdb:HMDB0000122 | |
| Sucrose | Metabolite | hmdb:HMDB0000258 | |
| UDP-Glucose | Metabolite | pubchem.compound:8629 | |
| Triosephosphate | Metabolite | pubchem.compound:729 | |
| Maltose | Metabolite | hmdb:HMDB0000163 | |
| Sucrose | Metabolite | hmdb:HMDB0000258 | |
| UDP-Glucose | Metabolite | pubchem.compound:8629 | |
| ATB2 | GeneProduct | ensembl:AT1G60710 | |
| NIA2 | GeneProduct | ensembl:AT1G37130 | |
| KIN10 | GeneProduct | ensembl:AT3G01090 | |
| HXK1 | GeneProduct | ensembl:AT4G29130 | |
| HMG1 | GeneProduct | ensembl:AT1G76490 | |
| KIN11 | GeneProduct | ensembl:AT3G29160 | |
| SPS1 | GeneProduct | ensembl:AT5G20280 | |
| GPA1 | GeneProduct | ensembl:AT2G26300 | |
| TPS1 | GeneProduct | ensembl:AT1G78580 | |
| proteasome | GeneProduct | uniprot:P34066 | |
| EIN3 | GeneProduct | ensembl:AT3G20770 | |
| HXK1 | GeneProduct | ensembl:AT4G29130 | |
| RGS1 | GeneProduct | ensembl:AT3G26090 | |
| THF1 | GeneProduct | ensembl:AT2G20890 | |
| ADG2 | GeneProduct | ensembl:AT5G19220 | |
| HXK2 | GeneProduct | ensembl:AT2G19860 | |
| HXK3 | GeneProduct | ensembl:AT1G47840 | |
| HXK1 | GeneProduct | ensembl:AT4G29130 | |
| HXK2 | GeneProduct | ensembl:AT2G19860 | |
| HXK3 | GeneProduct | ensembl:AT1G47840 |
References
- Sugar sensing and signaling. Ramon M, Rolland F, Sheen J. Arabidopsis Book. 2008;6:e0117. PubMed Europe PMC Scholia