Folic acid network (WP1273)

Mus musculus

Authors

Kristina Hanspers , Samuel Sklar , Egon Willighagen , Christine Chichester , Laurent Winckers , Eric Weitz , and Alex Pico

Activity

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Cited In

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Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

folate metabolic pathway

References

1. Cystathionine beta-synthase deficiency: a qualitative abnormality of the deficient enzyme modified by vitamin B6 therapy. Longhi RC, Fleisher LD, Tallan HH, Gaull GE. Pediatr Res. 1977 Feb;11(2):100–3. PubMed Europe PMC Scholia
2. Transcobalamins I and II as natural transport proteins of vitamin B12. Hall CA. J Clin Invest. 1975 Nov;56(5):1125–31. PubMed Europe PMC Scholia
3. Vitamin B12 binders (transcobalamins) in serum. Fernandes-Costa F, Metz J. Crit Rev Clin Lab Sci. 1982;18(1):1–30. PubMed Europe PMC Scholia
4. Synthesis and biological activities of leukotriene F4 and leukotriene F4 sulfone. Denis D, Charleson S, Rackham A, Jones TR, Ford-Hutchinson AW, Lord A, et al. Prostaglandins. 1982 Dec;24(6):801–14. PubMed Europe PMC Scholia
5. The isoprostanes. Current knowledge and directions for future research. Morrow JD, Roberts LJ 2nd. Biochem Pharmacol. 1996 Jan 12;51(1):1–9. PubMed Europe PMC Scholia
6. Free radicals, uric acid, and human disease. Proctor PH. Free Radic Biol Med. 1996;20(5):761–2. PubMed Europe PMC Scholia
7. Human methionine synthase: cDNA cloning and identification of mutations in patients of the cblG complementation group of folate/cobalamin disorders. Leclerc D, Campeau E, Goyette P, Adjalla CE, Christensen B, Ross M, et al. Hum Mol Genet. 1996 Dec;5(12):1867–74. PubMed Europe PMC Scholia
8. A common variant in methionine synthase reductase combined with low cobalamin (vitamin B12) increases risk for spina bifida. Wilson A, Platt R, Wu Q, Leclerc D, Christensen B, Yang H, et al. Mol Genet Metab. 1999 Aug;67(4):317–23. PubMed Europe PMC Scholia
9. Homocysteine metabolism. Selhub J. Annu Rev Nutr. 1999;19:217–46. PubMed Europe PMC Scholia
10. Domain alternation switches B(12)-dependent methionine synthase to the activation conformation. Bandarian V, Pattridge KA, Lennon BW, Huddler DP, Matthews RG, Ludwig ML. Nat Struct Biol. 2002 Jan;9(1):53–6. PubMed Europe PMC Scholia
11. Selenoprotein R is a zinc-containing stereo-specific methionine sulfoxide reductase. Kryukov GV, Kumar RA, Koc A, Sun Z, Gladyshev VN. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4245–50. PubMed Europe PMC Scholia
12. Nitric oxide and superoxide in inflammation and immune regulation. Guzik TJ, Korbut R, Adamek-Guzik T. J Physiol Pharmacol. 2003 Dec;54(4):469–87. PubMed Europe PMC Scholia
13. Isoprostanes: novel bioactive products of lipid peroxidation. Basu S. Free Radic Res. 2004 Feb;38(2):105–22. PubMed Europe PMC Scholia
14. Vitamin E, oxidative stress, and inflammation. Singh U, Devaraj S, Jialal I. Annu Rev Nutr. 2005;25:151–74. PubMed Europe PMC Scholia
15. Homocysteine: overview of biochemistry, molecular biology, and role in disease processes. Fowler B. Semin Vasc Med. 2005 May;5(2):77–86. PubMed Europe PMC Scholia
16. Identification and characterization of selenoprotein K: an antioxidant in cardiomyocytes. Lu C, Qiu F, Zhou H, Peng Y, Hao W, Xu J, et al. FEBS Lett. 2006 Oct 2;580(22):5189–97. PubMed Europe PMC Scholia
17. Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. Petersen Shay K, Moreau RF, Smith EJ, Hagen TM. IUBMB Life. 2008 Jun;60(6):362–7. PubMed Europe PMC Scholia
18. The role of urate and xanthine oxidase inhibitors in cardiovascular disease. George J, Struthers AD. Cardiovasc Ther. 2008;26(1):59–64. PubMed Europe PMC Scholia
19. A network biology model of micronutrient related health. van Ommen B, Fairweather-Tait S, Freidig A, Kardinaal A, Scalbert A, Wopereis S. Br J Nutr. 2008 Jun;99 Suppl 3:S72-80. PubMed Europe PMC Scholia