Phase I biotransformations, non-P450 (WP1291)

Rattus norvegicus

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This pathway lists several phase 1 biotransformations and their related enzymes.

Authors

Daniela Digles , Kristina Hanspers , Martina Summer-Kutmon , Lars Willighagen , and Eric Weitz

Activity

last edited

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Organisms

Rattus norvegicus

Communities

Annotations

Pathway Ontology

cytochrome P450-independent phase I biotransformation pathway

Participants

Label Type Compact URI Comment
thio esters Metabolite chebi:51277
Phosphoric acid esters Metabolite chebi:37734
carboxylic acid esters Metabolite chebi:33308
amides Metabolite chebi:32988
Ces5a GeneProduct ensembl:ENSRNOG00000025710 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000159398
Esd GeneProduct ensembl:ENSRNOG00000009512 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000139684
Lipa GeneProduct ensembl:ENSRNOG00000019077 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000107798
Pon3 GeneProduct ensembl:ENSRNOG00000009096 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000105852
Ces2j GeneProduct ensembl:ENSRNOG00000029744 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000172831
Pon2 GeneProduct ensembl:ENSRNOG00000009112 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000105854
Ces1a GeneProduct ensembl:ENSRNOG00000039725 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000198848
Pon1 GeneProduct ensembl:ENSRNOG00000008902 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000005421

References

  1. Casarett & Doull’s Essentials of Toxicology [Internet]. Klaassen C, Watkins JB III. McGraw-Hill Professional; 2003. 548 p. Available from: https://books.google.com/books/about/Casarett_Doull_s_Essentials_of_Toxicolog.html?hl=&id=pj5iQgAACAAJ OpenLibrary Worldcat