Phase I biotransformations, non P450 (WP1291)

Rattus norvegicus

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This pathway lists several phase 1 biotransformations and their related enzymes.

Authors

Daniela Digles , Kristina Hanspers , Martina Summer-Kutmon , and Lars Willighagen

Activity

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Organisms

Rattus norvegicus

Communities

Annotations

Pathway Ontology

cytochrome P450-independent phase I biotransformation pathway

Participants

Label Type Compact Identifier Comment
thio esters Metabolite chebi:51277
Phosphoric acid esters Metabolite chebi:37734
thio esters Metabolite chebi:51277
carboxylic acid esters Metabolite chebi:33308
amides Metabolite chebi:32988
carboxylic acid esters Metabolite chebi:33308
Phosphoric acid esters Metabolite chebi:37734
amides Metabolite chebi:32988
Ces5a GeneProduct ensembl:ENSRNOG00000025710 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000159398
Esd GeneProduct ensembl:ENSRNOG00000009512 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000139684
Lipa GeneProduct ensembl:ENSRNOG00000019077 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000107798
Pon3 GeneProduct ensembl:ENSRNOG00000009096 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000105852
Ces2j GeneProduct ensembl:ENSRNOG00000029744 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000172831
Pon2 GeneProduct ensembl:ENSRNOG00000009112 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000105854
Ces1a GeneProduct ensembl:ENSRNOG00000039725 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000198848
Pon1 GeneProduct ensembl:ENSRNOG00000008902 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000005421

References

  1. Watkins JB, Klaassen CD. Casarett and Doull’s essentials of toxicology [Internet]. New York: McGraw-Hill Medical Pub. Division; 2003. 533 p. Available from: https://openlibrary.org/books/OL17085521M/Casarett_and_Doull’s_essentials_of_toxicology OpenLibrary Worldcat