Blood clotting cascade (WP460)

Mus musculus

Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [[wikipedia:Coagulation|Wikipedia]]


Andrew Kwa , Thomas Kelder , Christine Chichester , and Eric Weitz


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Mus musculus



Pathway Ontology

coagulation cascade pathway


Label Type Compact URI Comment
F12 GeneProduct ncbigene:58992
F11 GeneProduct ncbigene:109821
F9 GeneProduct ncbigene:14071
F10 GeneProduct ncbigene:14058
F10 GeneProduct ncbigene:14058
Vwf GeneProduct ncbigene:22371
F5 GeneProduct ncbigene:14067
F7 GeneProduct ncbigene:14068
F2 GeneProduct ncbigene:14061
F13b GeneProduct ncbigene:14060
Serpinf2 GeneProduct ncbigene:18816
Plau GeneProduct ncbigene:18792
Plat GeneProduct ncbigene:18791
Serpinb2 GeneProduct ncbigene:18788
Serpine1 GeneProduct ncbigene:18787
Plg GeneProduct ncbigene:18815
Fgb GeneProduct ncbigene:110135
Fga GeneProduct ncbigene:14161
Fgg GeneProduct ncbigene:99571
F8 GeneProduct ncbigene:14069
F8a GeneProduct ncbigene:14070


  1. The current status of coagulation. Luchtman-Jones L, Broze GJ Jr. Ann Med. 1995 Feb;27(1):47–52. PubMed Europe PMC Scholia