HIPK2 in kidney fibrosis (WP4751)
This pathway shows the activation of multiple signaling pathways involved in kidney fibrosis, starting from an insult like HIV infection or oxidative stress, through the suppression of SIAH1 and increased expression of HIPK2. This pathway was adapted from Figure 6i of [https://pubmed.ncbi.nlm.nih.gov/22406746/ Jin et. al.]
AuthorsAgustin Gonzalez-Vicente , Kristina Hanspers , and Egon Willighagen
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OrganismsHomo sapiens Diseases Renal Genomics Pathways
Disease Ontologyrenal fibrosis
Pathway Ontologykidney disease pathway