GPCRs, class A rhodopsin-like (WP189)

Mus musculus

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This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.

Authors

Nathan Salomonis , Bruce Conklin , Kristina Hanspers , Christine Chichester , Egon Willighagen , and Eric Weitz

Activity

last edited

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Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

G protein mediated signaling pathway

Participants

Label Type Compact URI Comment
Thromboxane Metabolite chebi:26995
Dopamine Metabolite cas:62-31-7
Histamine Metabolite cas:51-45-6
Melatonin Metabolite hmdb:HMDB0001389
Serotonin Metabolite cas:50-67-9
Olfr888 GeneProduct ncbigene:258416
Olfr959 GeneProduct ncbigene:258501
Sstr2 GeneProduct ncbigene:20606
Avpr1a GeneProduct ncbigene:54140
Bdkrb2 GeneProduct ncbigene:12062
Olfr968 GeneProduct ncbigene:258605 ��Ω��Ω258603[L] ��Ω��Ω
Adrb1 GeneProduct ncbigene:11554
Gpr45 GeneProduct ncbigene:93690
Olfr970 GeneProduct ncbigene:258604
Mc2r GeneProduct ncbigene:17200
Olfr957 GeneProduct ncbigene:258740
Npy6r GeneProduct ncbigene:18169
Olfr948 GeneProduct uniprot:Q9EQ95
Avpr1b GeneProduct ncbigene:26361
Olfr876 GeneProduct ncbigene:258883
Olfr708 GeneProduct ncbigene:258173
Agtrl1 GeneProduct ncbigene:23796
Gpr83 GeneProduct ncbigene:14608
P2ry13 GeneProduct ncbigene:74191
Adora2a GeneProduct ncbigene:11540
Olfr870 GeneProduct ncbigene:57251
Htr1a GeneProduct ncbigene:15550
Drd4 GeneProduct ncbigene:13491
Olfr749 GeneProduct ncbigene:56858
Olfr933 GeneProduct ncbigene:258433
Sstr5 GeneProduct ncbigene:20609
Drd3 GeneProduct ncbigene:13490
Olfr703 GeneProduct ncbigene:258589
Olfr705 GeneProduct ncbigene:259034
Ntsr2 GeneProduct ncbigene:18217
Sstr3 GeneProduct ncbigene:20607
Fshr GeneProduct ncbigene:14309
Gpr35 GeneProduct ncbigene:64095
Ccr2 GeneProduct ncbigene:12772
Rho GeneProduct ncbigene:212541
Mc1r GeneProduct ncbigene:17199
Hrh1 GeneProduct ncbigene:15465
Olfr713 GeneProduct ncbigene:259036
Olfr70 GeneProduct ncbigene:56014
Htr4 GeneProduct ncbigene:15562
Tbxa2r GeneProduct ncbigene:21390
Galr1 GeneProduct ncbigene:14427
Olfr971 GeneProduct ncbigene:258607
Galr3 GeneProduct ncbigene:14429
Ptger4 GeneProduct ncbigene:19219
Olfr893 GeneProduct ncbigene:258333
Oprl1 GeneProduct ncbigene:18389
Brs3 GeneProduct ncbigene:12209
Cmklr1 GeneProduct ncbigene:14747
Olfr889 GeneProduct ncbigene:258475
Gpr37 GeneProduct ncbigene:14763
Opn4 GeneProduct ncbigene:30044
Olfr707 GeneProduct ncbigene:194433
Cckar GeneProduct ncbigene:12425
Agtr1b GeneProduct ncbigene:11608
Olfr71 GeneProduct ncbigene:56015
Olfr16 GeneProduct ncbigene:18313
Olfr715 GeneProduct ncbigene:258776
Cxcr3 GeneProduct ncbigene:12766
Olfr716 GeneProduct ncbigene:258597
Gpr30 GeneProduct ncbigene:76854
Olfr1355 GeneProduct ncbigene:404334
Chrm4 GeneProduct ncbigene:12672
Q9EPV1 GeneProduct uniprot:Q9EPV1
Opn3 GeneProduct ncbigene:13603
Gpr50 GeneProduct ncbigene:14765
Olfr704 GeneProduct uniprot:Q9EPF6
Sstr1 GeneProduct ncbigene:20605
Htr1b GeneProduct ncbigene:15551
Adra2a GeneProduct ncbigene:11551
Avpr2 GeneProduct ncbigene:12000
Cnr1 GeneProduct ncbigene:12801
Ccr1 GeneProduct ncbigene:12768
Hrh2 GeneProduct ncbigene:15466
Adra2b GeneProduct ncbigene:11552
Gpr27 GeneProduct ncbigene:14761
Gpr3 GeneProduct ncbigene:14748
Galr2 GeneProduct ncbigene:14428
Ntsr1 GeneProduct ncbigene:18216
Bdkrb1 GeneProduct ncbigene:12061
Ptger1 GeneProduct ncbigene:19216
Q9EQ94 GeneProduct uniprot:Q9EQ94
Adrb3 GeneProduct ncbigene:11556
Olfr144 GeneProduct ncbigene:257959
Agtr2 GeneProduct ncbigene:11609
Ednrb GeneProduct ncbigene:13618
Gpr33 GeneProduct ncbigene:14762
Cnr2 GeneProduct ncbigene:12802
Mas1 GeneProduct ncbigene:17171
Olfr155 GeneProduct ncbigene:29845
Olfr945 GeneProduct ncbigene:258499
Ptafr GeneProduct ncbigene:19204
Olfr160 GeneProduct ncbigene:80706
P2ry6 GeneProduct ncbigene:233571
Olfr148 GeneProduct ncbigene:258498
Ptgdr GeneProduct ncbigene:19214
Trhr2 GeneProduct ncbigene:170732
Fpr-rs4 GeneProduct ncbigene:14291
Agtr1 GeneProduct ncbigene:11607
Olfr944 GeneProduct ncbigene:258500 ��Ω��Ω258500[L] ��Ω��Ω
Htr5b GeneProduct ncbigene:15564
Trhr GeneProduct ncbigene:22045
Blr1 GeneProduct ncbigene:12145
Chrm1 GeneProduct ncbigene:12669
Htr5a GeneProduct ncbigene:15563
Il8rb GeneProduct ncbigene:12765
Mtnr1a GeneProduct ncbigene:17773
P2ry2 GeneProduct ncbigene:18442
Npy5r GeneProduct ncbigene:18168
Lhcgr GeneProduct ncbigene:16867
Gpr63 GeneProduct ncbigene:81006
Adora3 GeneProduct ncbigene:11542
Olfr955 GeneProduct ncbigene:258242
Htr1f GeneProduct ncbigene:15557
Olfr710 GeneProduct ncbigene:258594
F2r GeneProduct ncbigene:14062
Olfr145 GeneProduct ncbigene:258310
C3ar1 GeneProduct ncbigene:12267
Adra2c GeneProduct ncbigene:11553
Adra1d GeneProduct ncbigene:11550
Olfr961 GeneProduct ncbigene:258497
F2rl2 GeneProduct ncbigene:14064
Chrm2 GeneProduct ncbigene:243764
Sstr4 GeneProduct ncbigene:20608
Ltb4r1 GeneProduct ncbigene:16995
Olfr894 GeneProduct ncbigene:258868
Adra1a GeneProduct ncbigene:11549
Gabbr1 GeneProduct ncbigene:54393
Olfr938 GeneProduct ncbigene:258430
Olfr874 GeneProduct ncbigene:258882
Adra1b GeneProduct ncbigene:11548
Mc5r GeneProduct ncbigene:17203
Olfr926 GeneProduct ncbigene:258811
Gpr19 GeneProduct ncbigene:14760
Tcp10c GeneProduct ncbigene:21462
Olfr954 GeneProduct ncbigene:258328
Gpr34 GeneProduct ncbigene:23890
F2rl3 GeneProduct ncbigene:14065
Htr6 GeneProduct ncbigene:15565
Ccr9 GeneProduct ncbigene:12769
Ptgfr GeneProduct ncbigene:19220
Htr7 GeneProduct ncbigene:15566
Olfr934 GeneProduct ncbigene:258434
Oxt GeneProduct ncbigene:18429
Fprl1 GeneProduct ncbigene:14294
Fpr-rs1 GeneProduct ncbigene:14288
Opn1sw GeneProduct ncbigene:12057
Ccr3 GeneProduct ncbigene:12771
Gpr87 GeneProduct ncbigene:84111
P2ry1 GeneProduct ncbigene:18441
Ccr1l1 GeneProduct ncbigene:12770
Olfr242 GeneProduct ncbigene:406175 ��Ω��Ω258500[L] ��Ω��Ω
Htr2b GeneProduct ncbigene:15559
Gpr12 GeneProduct ncbigene:14738
Olfr151 GeneProduct ncbigene:406176
P2ry14 GeneProduct ncbigene:140795
Olfr15 GeneProduct ncbigene:18312
Olfr972 GeneProduct ncbigene:258603 ��Ω��Ω258603[L] ��Ω��Ω
Ptger2 GeneProduct ncbigene:19217
Ccr4 GeneProduct ncbigene:12773
Olfr701 GeneProduct ncbigene:66786
Olfr711 GeneProduct ncbigene:259037
Olfr878 GeneProduct ncbigene:258794
Olfr930 GeneProduct ncbigene:258269
Sucnr1 GeneProduct ncbigene:84112
Q9EPG0 GeneProduct uniprot:Q9EPG0_MOUSE
Olfr27 GeneProduct ncbigene:258826
Oprm1 GeneProduct ncbigene:18390
Olfr887 GeneProduct ncbigene:258415
Oxtr GeneProduct ncbigene:18430
Fpr1 GeneProduct ncbigene:14293
Oprd1 GeneProduct ncbigene:18386
Fpr-rs3 GeneProduct ncbigene:14290
Olfr49 GeneProduct ncbigene:18348
Ccr8 GeneProduct ncbigene:12776
Olfr143 GeneProduct ncbigene:258802
Cx3cr1 GeneProduct ncbigene:13051
Olfr480 GeneProduct ncbigene:56861
Ptger3 GeneProduct ncbigene:19218
Gpr65 GeneProduct ncbigene:14744
Cckbr GeneProduct ncbigene:12426
Ccrl2 GeneProduct ncbigene:54199
Rgr GeneProduct ncbigene:57811
Cysltr1 GeneProduct ncbigene:58861
Olfr159 GeneProduct ncbigene:29849
Ptgir GeneProduct ncbigene:19222
Olfr943 GeneProduct ncbigene:258323
Olfr714 GeneProduct ncbigene:259035
Oprk1 GeneProduct ncbigene:18387
Htr1d GeneProduct ncbigene:15552
Nmbr GeneProduct ncbigene:18101
Nmur1 GeneProduct ncbigene:14767
Htr2c GeneProduct ncbigene:15560
F2rl1 GeneProduct ncbigene:14063
Ppyr1 GeneProduct ncbigene:19065
Gpr37l1 GeneProduct ncbigene:171469
Olfr44 GeneProduct ncbigene:18343
Adora2b GeneProduct ncbigene:11541
Olfr19 GeneProduct ncbigene:18316
Gpr109b GeneProduct ncbigene:80885
Ccbp2 GeneProduct ncbigene:59289
P2ry12 GeneProduct ncbigene:70839
Avp GeneProduct ncbigene:11998
Opn1mw GeneProduct ncbigene:14539
Olfr146 GeneProduct ncbigene:258742
Adrb2 GeneProduct ncbigene:11555
Npy1r GeneProduct ncbigene:18166
Rrh GeneProduct ncbigene:20132
Olfr2 GeneProduct ncbigene:18317
Gpr44 GeneProduct ncbigene:14764
Olfr17 GeneProduct ncbigene:18314
Npy2r GeneProduct ncbigene:18167
Olfr6 GeneProduct ncbigene:233670
Olfr960 GeneProduct ncbigene:258276
Olfr937 GeneProduct ncbigene:258431
Mc4r GeneProduct ncbigene:17202
P2ry4 GeneProduct ncbigene:57385
Olfr157 GeneProduct ncbigene:29847
Olfr156 GeneProduct ncbigene:29846
Chrm3 GeneProduct ncbigene:12671
C5r1 GeneProduct ncbigene:12273
Fpr-rs2 GeneProduct ncbigene:14289
Htr2a GeneProduct ncbigene:15558
Cxcr4 GeneProduct ncbigene:12767
Ccr5 GeneProduct ncbigene:12774
Ccr6 GeneProduct ncbigene:12458
Grpr GeneProduct ncbigene:14829
Olfr706 GeneProduct ncbigene:258350
Tshr GeneProduct ncbigene:22095
Mc3r GeneProduct ncbigene:17201
Cmkor1 GeneProduct ncbigene:12778

References

  1. GPCRDB: an information system for G protein-coupled receptors. Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, et al. Nucleic Acids Res. 1998 Jan 1;26(1):275–9. PubMed Europe PMC Scholia
  2. Classifying G-protein coupled receptors with support vector machines. Karchin R, Karplus K, Haussler D. Bioinformatics. 2002 Jan;18(1):147–59. PubMed Europe PMC Scholia