TCA cycle (WP434)

Mus musculus

The [[wikipedia:citric_acid_cycle|citric acid cycle]], also known as the tricarboxylic acid cycle (TCA cycle) or the Krebs cycle, (or rarely, the Szent-Gyorgyi-Krebs cycle) is a series of enzyme-catalysed chemical reactions of central importance in all living cells that use oxygen as part of cellular respiration. In eukaryotes, the citric acid cycle occurs in the matrix of the mitochondrion. The components and reactions of the citric acid cycle were established by seminal work from both [[wikipedia:Albert_Szent-Gyorgyi|Albert Szent-Gyorgyi]] and [[wikipedia:Hans_Krebs|Hans Krebs]]. [From [[wikipedia:Main_Page|Wikipedia]]]

Authors

Kdahlquist , Meredith Braymer , Adrien Defay , Martijn Van Iersel , Martina Summer-Kutmon , Daniela Digles , Egon Willighagen , and Eric Weitz

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Mus musculus

Communities

Annotations

Pathway Ontology

citric acid cycle pathway

Participants

Label Type Compact URI Comment
Oxaloacetate Metabolite hmdb:HMDB0000223
Malate Metabolite hmdb:HMDB0000156
Isocitrate Metabolite hmdb:HMDB0000193
Succinate Metabolite hmdb:HMDB0000254
Pyruvate Metabolite hmdb:HMDB0000243
Acetyl-CoA Metabolite hmdb:HMDB0001206
Citrate Metabolite hmdb:HMDB0000094
Fumarate Metabolite hmdb:HMDB0000134
Succinyl-CoA Metabolite hmdb:HMDB0001022
Pcx GeneProduct ncbigene:18563
Pdha1 GeneProduct ncbigene:18597
Pdhb GeneProduct ncbigene:68263
Pdk4 GeneProduct ncbigene:27273
Idh3b GeneProduct ncbigene:170718
Pdhx GeneProduct ncbigene:27402
Dlat GeneProduct ncbigene:235339
Dld GeneProduct ncbigene:13382
Sdha GeneProduct ncbigene:66945
Mdh1 GeneProduct ncbigene:17449
Suclg2 GeneProduct ncbigene:20917
Aco2 GeneProduct ncbigene:11429
Ppm2c GeneProduct ncbigene:381511
Suclg1 GeneProduct ncbigene:56451
Dlst GeneProduct ncbigene:78920
Pdk2 GeneProduct ncbigene:18604
Idh3g GeneProduct ncbigene:15929
Sdhc GeneProduct ncbigene:66052
Pdk1 GeneProduct ncbigene:228026
Sdhd GeneProduct ncbigene:66925
Sdhb GeneProduct ncbigene:67680
Cs GeneProduct ncbigene:12974
Sucla2 GeneProduct ncbigene:20916
Idh3a GeneProduct ncbigene:67834
Pdk3 GeneProduct ncbigene:236900
Idh2 GeneProduct ncbigene:269951
Ogdh GeneProduct ncbigene:18293
Pdha2 GeneProduct ncbigene:18598
4833426J09Rik GeneProduct ncbigene:382051
Fh1 GeneProduct ncbigene:14194
Mdh2 GeneProduct ncbigene:17448

References