Adipogenesis (WP1331)

Danio rerio

The different classess of factors involved in adipogenesis are shown. Adipogenesis is the process by which fat cells differentiate from predadipocytes to adipocytes (fat cells). Adipose tissue, composed of white and brown adipose tissue, is composed of adipocytes. This pathway is primarily studied to understand factors that contribute to obesity and diabetes. Transcriptional and hormonal regulators of adipocyte formation are indicated.


Martijn Van Iersel , Kristina Hanspers , Martina Summer-Kutmon , and Egon Willighagen


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Danio rerio



Pathway Ontology

signaling pathway pertinent to development


Label Type Compact URI Comment
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bmp1a GeneProduct ensembl:ENSDARG00000028071
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hnf1a GeneProduct ncbigene:266961
frzb GeneProduct ncbigene:30119
ins GeneProduct ncbigene:30262
LOC797300 GeneProduct ncbigene:797300
zgc:76966 GeneProduct ncbigene:405805
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nr2f1a GeneProduct ncbigene:30418
roraa GeneProduct ncbigene:564951
cugbp1 GeneProduct ncbigene:58137
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copeb GeneProduct ncbigene:280650
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ncor1 GeneProduct ncbigene:393246
ncor2 GeneProduct ncbigene:561503
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egr2b GeneProduct ncbigene:30190
LOC565310 GeneProduct ncbigene:565310
epas1 GeneProduct ncbigene:555192
ahr1b GeneProduct ncbigene:554265
wwtr1 GeneProduct ncbigene:568008
si:ch211-134j6.3 GeneProduct ncbigene:563003
LOC559281 GeneProduct ncbigene:559281
zgc:123260 GeneProduct ncbigene:567403
lmna GeneProduct ncbigene:195815
AGPAT2 GeneProduct ncbigene:777624
zmpste24 GeneProduct ncbigene:334380
lpin1 GeneProduct ncbigene:799099
LOC558422 GeneProduct ncbigene:558422
pck1 GeneProduct ncbigene:378727
zgc:77867 GeneProduct ncbigene:406473
cebpa GeneProduct ncbigene:140815
e2f4 GeneProduct ncbigene:406741


  1. Molecular regulation of adipogenesis. Rosen ED, Spiegelman BM. Annu Rev Cell Dev Biol. 2000;16:145–71. PubMed Europe PMC Scholia