Tryptophan metabolism (WP3248)
Bos taurus
This pathway describes the metabolism of tryptophan, an essential amino acid. Originally converted from rat to human using ortholog information. Edited by Sebastien Burel
Authors
Martina Summer-Kutmon , Egon Willighagen , Mick Eikelhof , Friederike Ehrhart , and Kristina HanspersActivity
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Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
tryptophan metabolic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| 4-(2-Aminophenyl)-2,4-dioxobutanoate | Metabolite | chemspider:19951260 | 4-(2-Aminophenyl)-2,4-dioxobutanoate |
| Indolelactate | Metabolite | chemspider:28571995 | Indolelactate |
| Indole-3-acetate | Metabolite | chemspider:779 | Indole-3-acetate |
| 4,8-Dihydroxyquinoline | Metabolite | chemspider:389608 | 4,8-Dihydroxyquinoline |
| 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate | Metabolite | chemspider:389617 | 4-(2-Amino-5-hydroxyphenyl)-2,4-dioxobutanoate |
| Oxaloacetate | Metabolite | chemspider:2509917 | Oxaloacetate |
| 3-(2-Aminoethyl)-1H-indol-5-ol | Metabolite | chemspider:5013 | 3-(2-Aminoethyl)-1H-indol-5-ol |
| Indolepyruvate | Metabolite | chemspider:24775813 | Indolepyruvate |
| Indole-3-acetaldehyde | Metabolite | chemspider:778 | Indole-3-acetaldehyde |
| 5-Methoxyindoleacetate | Metabolite | chemspider:14533147 | 5-Methoxyindoleacetate |
| 3-Hydroxyanthranilate | Metabolite | chemspider:7822291 | 3-Hydroxyanthranilate |
| Indole-3-acetaldoxime | Metabolite | chemspider:388896 | Indole-3-acetaldoxime |
| Indole-3-ethanol | Metabolite | chemspider:10235 | |
| Anthranilate | Metabolite | chemspider:4573598 | Anthranilate |
| Anthranilate | Metabolite | chemspider:4573598 | Anthranilate |
| 2-Formylaminobenzaldehyde | Metabolite | chemspider:389 | |
| 2,3-Dihydroxyindole | Metabolite | chemspider:20546 | |
| Quinolinate | Metabolite | chemspider:2777129 | |
| 3-Methoxyanthranilate | Metabolite | chemspider:7827589 | 3-Methoxyanthranilate |
| 2-Oxoglutarate | Metabolite | chemspider:144236 | 2-Oxoglutarate |
| 2-Oxoadipate | Metabolite | chemspider:19951093 | 2-Oxoadipate |
| 5-Hydroxyindoleacetate | Metabolite | chemspider:10637170 | 5-Hydroxyindoleacetate |
| 5-(3'-Carboxy-3'-oxopropyl) -4,6-dihydroxypicolinate | Metabolite | chemspider:30791292 | 5-(3'-Carboxy-3'-oxopropyl)-4,6-dihydroxypicolinate |
| 5-(2'-Formylethyl)-4,6-dihydroxypicolinate | Metabolite | chemspider:30791294 | 5-(2'-Formylethyl)-4,6-dihydroxypicolinate |
| 3-Indoleglycolaldehyde | Metabolite | chemspider:388979 | |
| Formylkynurenine | Metabolite | cas:1022-31-7 | Formylkynurenine |
| 4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate | Metabolite | hmdb:HMDB0004083 | |
| Acetyl-CoA | Metabolite | cas:72-89-9 | Acetyl-CoA |
| Indole | Metabolite | cas:120-72-9 | |
| 5-Methoxytryptamine | Metabolite | cas:608-07-1 | |
| 5-Hydroxy-L-tryptophan | Metabolite | hmdb:HMDB0000472 | |
| L-Kynurenine | Metabolite | cas:343-65-7 | L-Kynurenine |
| Melatonin | Metabolite | hmdb:HMDB0001389 | |
| 5-Hydroxykynurenine | Metabolite | cas:484-78-6 | |
| Xanthurenic acid | Metabolite | hmdb:HMDB0000881 | |
| N-Methylserotonin | Metabolite | hmdb:HMDB0004369 | |
| Tryptamine | Metabolite | cas:61-54-1 | |
| 5-Hydroxy-N-formylkynurenine | Metabolite | hmdb:HMDB0004086 | |
| 4,6-Dihydroxyquinoline | Metabolite | hmdb:HMDB0004077 | |
| N-Acetylisatin | Metabolite | cas:574-17-4 | N-Acetylisatin |
| L-Tryptophan | Metabolite | cas:73-22-3 | |
| Indole-3-acetamide | Metabolite | cas:879-37-8 | Indole-3-acetamide |
| Acetoacetyl-CoA | Metabolite | kegg.compound:C00332 | |
| N-Methyltryptamine | Metabolite | chebi:28136 | |
| Crotonoyl-CoA | Metabolite | kegg.compound:C00877 | |
| 5-(2'-Carboxyethyl)-4,6-Dihydroxypicolinate | Metabolite | hmdb:HMDB0006794 | |
| 3-Indoleacetonitrile | Metabolite | cas:771-51-7 | 3-Indoleacetonitrile |
| 5-Hydroxyindoleacetaldehyde | Metabolite | hmdb:HMDB0004073 | |
| 2-Aminophenol | Metabolite | cas:95-55-6 | 2-Aminophenol |
| 6-Hydroxymelatonin | Metabolite | cas:2208-41-5 | |
| Glutaryl-CoA | Metabolite | kegg.compound:C00527 | |
| N-Acetylserotonin | Metabolite | cas:1210-83-9 | N-Acetylserotonin |
| CYP4F12 | GeneProduct | ensembl:ENSBTAG00000038549 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:66002 |
| UBR5 | GeneProduct | ensembl:ENSBTAG00000021209 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51366 |
| IDO1 | GeneProduct | ensembl:ENSBTAG00000020602 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3620 |
| CYP2E1 | GeneProduct | ensembl:ENSBTAG00000018365 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1571 |
| RNF25 | GeneProduct | ensembl:ENSBTAG00000003817 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:64320 |
| GCDH | GeneProduct | ensembl:ENSBTAG00000016211 | predictedHomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2639 |
| ALDH9A1 | GeneProduct | ensembl:ENSBTAG00000017852 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:223 |
| HRMT1L2 | GeneProduct | ensembl:ENSBTAG00000001357 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3276 |
| ALDH2 | GeneProduct | ensembl:ENSBTAG00000008743 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:217 |
| ALDH1A2 | GeneProduct | ensembl:ENSBTAG00000010119 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8854 |
| ASMT | GeneProduct | ensembl:ENSBTAG00000047124 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:438 |
| CYP1A1 | GeneProduct | ensembl:ENSBTAG00000001021 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1543 |
| MDM2 | GeneProduct | ensembl:ENSBTAG00000010422 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4193 |
| OGDH | GeneProduct | ensembl:ENSBTAG00000006029 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4967 |
| MAOB | GeneProduct | ensembl:ENSBTAG00000001288 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4129 |
| ALDH3A2 | GeneProduct | ensembl:ENSBTAG00000039161 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:224 |
| MAOB | GeneProduct | ensembl:ENSBTAG00000001288 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4129 |
| DDC | GeneProduct | ensembl:ENSBTAG00000020869 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1644 |
| HSD17B10 | GeneProduct | ensembl:ENSBTAG00000017779 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3028 |
| ALDH9A1 | GeneProduct | ensembl:ENSBTAG00000017852 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:223 |
| CAT | GeneProduct | ensembl:ENSBTAG00000020980 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:847 |
| UBE3A | GeneProduct | ensembl:ENSBTAG00000002487 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7337 |
| HADH | GeneProduct | ensembl:ENSBTAG00000002049 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3033 |
| CYP3A4 | GeneProduct | ensembl:ENSBTAG00000047379 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1576 |
| ALDH3A2 | GeneProduct | ensembl:ENSBTAG00000039161 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:224 |
| DDC | GeneProduct | ensembl:ENSBTAG00000020869 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1644 |
| DDC | GeneProduct | ensembl:ENSBTAG00000020869 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1644 |
| ALDH2 | GeneProduct | ensembl:ENSBTAG00000008743 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:217 |
| MAOB | GeneProduct | ensembl:ENSBTAG00000001288 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4129 |
| MDM2 | GeneProduct | ensembl:ENSBTAG00000010422 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4193 |
| CYP7B1 | GeneProduct | ensembl:ENSBTAG00000001299 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:9420 |
| UBE3A | GeneProduct | ensembl:ENSBTAG00000002487 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7337 |
| AADAT | GeneProduct | ensembl:ENSBTAG00000010326 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51166 |
| ACAT1 | GeneProduct | ensembl:ENSBTAG00000012885 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:38 |
| IDO1 | GeneProduct | ensembl:ENSBTAG00000020602 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3620 |
| ALDH1A2 | GeneProduct | ensembl:ENSBTAG00000010119 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8854 |
| KYNU | GeneProduct | ensembl:ENSBTAG00000032277 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8942 |
| AFMID | GeneProduct | ensembl:ENSBTAG00000007125 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:125061 |
| CYP1B1 | GeneProduct | ensembl:ENSBTAG00000010531 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1545 |
| AANAT | GeneProduct | ensembl:ENSBTAG00000014682 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:15 |
| AOX1 | GeneProduct | ensembl:ENSBTAG00000009725 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:316 |
| DHCR24 | GeneProduct | ensembl:ENSBTAG00000004688 | predictedHomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1718 |
| AADAT | GeneProduct | ensembl:ENSBTAG00000010326 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:51166 |
| ACMSD | GeneProduct | ensembl:ENSBTAG00000008039 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:130013 |
| IDO1 | GeneProduct | ensembl:ENSBTAG00000020602 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3620 |
| KYNU | GeneProduct | ensembl:ENSBTAG00000032277 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8942 |
| CYP1A2 | GeneProduct | ensembl:ENSBTAG00000000085 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1544 |
| CYP2C18 | GeneProduct | ensembl:ENSBTAG00000020375 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1562 |
| WARS | GeneProduct | ensembl:ENSBTAG00000004679 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7453 |
| CYP2A13 | GeneProduct | ensembl:ENSBTAG00000047815 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1553 |
| INMT | GeneProduct | ensembl:ENSBTAG00000001448 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:11185 |
| CYP19A1 | GeneProduct | ensembl:ENSBTAG00000014890 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1588 |
| HRMT1L2 | GeneProduct | ensembl:ENSBTAG00000001357 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3276 |
| ALDH1A1 | GeneProduct | ensembl:ENSBTAG00000008103 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:216 |
| CYP2J2 | GeneProduct | ensembl:ENSBTAG00000013693 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1573 |
| HAAO | GeneProduct | ensembl:ENSBTAG00000004674 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:23498 |
| HRMT1L2 | GeneProduct | ensembl:ENSBTAG00000001357 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3276 |
| ABP1 | GeneProduct | ensembl:ENSBTAG00000005419 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:26 |
| RNF25 | GeneProduct | ensembl:ENSBTAG00000003817 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:64320 |
| MAOB | GeneProduct | ensembl:ENSBTAG00000001288 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4129 |
| KYNU | GeneProduct | ensembl:ENSBTAG00000032277 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:8942 |
| MDM2 | GeneProduct | ensembl:ENSBTAG00000010422 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4193 |
| ECHS1 | GeneProduct | ensembl:ENSBTAG00000017710 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1892 |
| TDO2 | GeneProduct | ensembl:ENSBTAG00000011062 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:6999 |
| CYP2F1 | GeneProduct | ensembl:ENSBTAG00000046805 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:1572 |
| GCDH | GeneProduct | ensembl:ENSBTAG00000016211 | predictedHomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2639 |
| TPH1 | GeneProduct | ensembl:ENSBTAG00000005343 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7166 |
| ALDH1A1 | GeneProduct | ensembl:ENSBTAG00000008103 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:216 |
| ASMT | GeneProduct | ensembl:ENSBTAG00000047124 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:438 |