TOR signaling (WP1489)

Caenorhabditis elegans


Pieter Giesbertz , Kristina Hanspers , Alex Pico , Webber51 , Daniela Digles , Stefan Raats , and Egon Willighagen


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Caenorhabditis elegans



Pathway Ontology

mTOR signaling pathway


Label Type Compact URI Comment
C10H11.8 GeneProduct ensembl:C10H11.8
let-363 GeneProduct wormbase:B0261.2
unc-51 GeneProduct wormbase:Y60A3A.1
par-4 GeneProduct wormbase:Y59A8B.14
let-363 GeneProduct wormbase:B0261.2
akt-2 GeneProduct wormbase:F28H6.1
aak-2 GeneProduct wormbase:T01C8.1
sinh-1 GeneProduct wormbase:Y57A10A.20
rheb-1 GeneProduct wormbase:F54C8.5
daf-15 GeneProduct wormbase:C10C5.6
C10H11.8 GeneProduct ensembl:WBGene00015697
rict-1 GeneProduct wormbase:F29C12.3
hif-1 GeneProduct wormbase:F38A6.3
akt-1 GeneProduct wormbase:C12D8.10
rps-6 GeneProduct wormbase:Y71A12B.1
sgk-1 GeneProduct wormbase:W10G6.2
rsks-1 GeneProduct wormbase:Y47D3A.16


  1. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Jia K, Chen D, Riddle DL. Development. 2004 Aug;131(16):3897–906. PubMed Europe PMC Scholia
  2. HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans. Chen D, Thomas EL, Kapahi P. PLoS Genet. 2009 May;5(5):e1000486. PubMed Europe PMC Scholia