Parkin-ubiquitin proteasomal system pathway (WP2359)

Homo sapiens

Authors

Kristina Hanspers , Daniela Digles , Alex Pico , Eric Weitz , Friederike Ehrhart , and Egon Willighagen

Activity

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Cited In

• Vitreous Humor Proteome: Targeting Oxidative Stress, Inflammation, and Neurodegeneration in Vitreoretinal Diseases (2022).
• Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypes in Fabry disease (2020).
• Altered Levels of Proteins and Phosphoproteins, in the Absence of Early Causative Transcriptional Changes, Shape the Molecular Pathogenesis in the Brain of Young Presymptomatic Ki91 SCA3/MJD Mouse (2019).
• Proteomics Analysis of Porcine Endometrial Cell-Derived Extracellular Vesicles Involved in Embryo Attachment (2025).

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

ubiquitin/proteasome degradation pathway

References

1. Identification of common biological pathways and drug targets across multiple respiratory viruses based on human host gene expression analysis. Smith SB, Dampier W, Tozeren A, Brown JR, Magid-Slav M. PLoS One. 2012;7(3):e33174. PubMed Europe PMC Scholia