Blood clotting cascade (WP3251)
Bos taurus
Coagulation is a complex process by which blood forms clots. It is an important part of hemostasis (the cessation of blood loss from a damaged vessel), wherein a damaged blood vessel wall is covered by a platelet and fibrin-containing clot to stop bleeding and begin repair of the damaged vessel. Disorders of coagulation can lead to an increased risk of bleeding (hemorrhage) or clotting (thrombosis). Source: [[wikipedia:Coagulation|Wikipedia]]
Authors
Martina Summer-Kutmon , Eric Weitz , and Egon WillighagenActivity
Discuss this pathway
Check for ongoing discussions or start your own.
Cited In
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Organisms
Bos taurusCommunities
Annotations
Pathway Ontology
coagulation cascade pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| Fibrin | Metabolite | cas:9001-31-4 | |
| Zinc | Metabolite | hmdb:HMDB0015532 | |
| F10 | GeneProduct | ensembl:ENSBTAG00000016385 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2159 |
| F2 | GeneProduct | ensembl:ENSBTAG00000007148 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2147 |
| F12 | GeneProduct | ensembl:ENSBTAG00000018872 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2161 |
| KLKB1 | GeneProduct | ensembl:ENSBTAG00000009501 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3818 |
| FGG | GeneProduct | ensembl:ENSBTAG00000006745 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2266 |
| F10 | GeneProduct | ensembl:ENSBTAG00000016385 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2159 |
| PLG | GeneProduct | ensembl:ENSBTAG00000001271 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5340 |
| F9 | GeneProduct | ensembl:ENSBTAG00000004003 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2158 |
| F2 | GeneProduct | ensembl:ENSBTAG00000007148 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2147 |
| PLAU | GeneProduct | ensembl:ENSBTAG00000005947 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5328 |
| FGB | GeneProduct | ensembl:ENSBTAG00000022120 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2244 |
| KLK1 | GeneProduct | ensembl:ENSBTAG00000018539 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:3816 |
| VWF | GeneProduct | ensembl:ENSBTAG00000012265 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:7450 |
| F13B | GeneProduct | ensembl:ENSBTAG00000000070 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2165 |
| F10 | GeneProduct | ensembl:ENSBTAG00000016385 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2159 |
| F11 | GeneProduct | ensembl:ENSBTAG00000003572 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2160 |
| SERPINF2 | GeneProduct | ensembl:ENSBTAG00000020859 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5345 |
| PLAT | GeneProduct | ensembl:ENSBTAG00000001244 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5327 |
| SERPINB2 | GeneProduct | ensembl:ENSBTAG00000023198 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5055 |
| SERPINE1 | GeneProduct | ensembl:ENSBTAG00000014465 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:5054 |
| F8 | GeneProduct | ensembl:ENSBTAG00000010726 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2157 |
| F7 | GeneProduct | ensembl:ENSBTAG00000007411 | HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:2155 |
References
- The current status of coagulation. Luchtman-Jones L, Broze GJ Jr. Ann Med. 1995 Feb;27(1):47–52. PubMed Europe PMC Scholia