CFTR activity in the plasma membrane (WP1488)

Rattus norvegicus

Mechanisms that regulate the Cl excretion by CFTR channel.


Karin , Kristina Hanspers , Christine Chichester , and Egon Willighagen


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Rattus norvegicus



Pathway Ontology

chloride ion transport pathway


Label Type Compact URI Comment
PKA GeneProduct ncbigene:25636
PLC zeta GeneProduct ncbigene:497197
PLC b2 GeneProduct ncbigene:85240
b2-AR GeneProduct ncbigene:24176
SYN1A GeneProduct ncbigene:24949
PLC b1 GeneProduct ncbigene:24654
PKC GeneProduct ncbigene:24681
CFTR GeneProduct ncbigene:24255
PDZ2 GeneProduct ncbigene:65144
PLC b3 GeneProduct ncbigene:29322
AMPK GeneProduct ncbigene:78975
SNAP23 GeneProduct ncbigene:64630
RACK1 GeneProduct ncbigene:83427
Rho GTPase GeneProduct ncbigene:689752
PDZ2 GeneProduct ncbigene:65144
PP2A GeneProduct ncbigene:24672
Ezrin GeneProduct ncbigene:54319
NHERF2 Protein ncbigene:116501
PDZ1 Protein ncbigene:65144
PDZ1 Protein ncbigene:65144
NHERF1 Protein ncbigene:59114


  1. New insights into cystic fibrosis: molecular switches that regulate CFTR. Guggino WB, Stanton BA. Nat Rev Mol Cell Biol. 2006 Jun;7(6):426–36. PubMed Europe PMC Scholia