Pantothenate and coenzyme A biosynthesis (WP462)

Saccharomyces cerevisiae

Coenzyme A is synthesized from pantothenate, which is made from beta-alanine and pantoate deriving from spermine and 2-keto-iosvalerate, respectively.


Meredith Braymer , Daniela Digles , Egon Willighagen , Scott Norton , Eric Weitz , and Alex Pico


last edited

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Saccharomyces cerevisiae



Pathway Ontology

coenzyme A biosynthetic pathway


Label Type Compact URI Comment
NADH Metabolite cas:53-84-9
5,10-methylene-THF Metabolite cas:31690-11-6
ATP Metabolite cas:1927-31-7
NADPH Metabolite cas:53-57-6
pyrophosphate Metabolite cas:2466-09-3
L-cysteine Metabolite cas:52-90-4
spermine Metabolite cas:71-44-3
ATP Metabolite cas:1927-31-7
pyrophosphate Metabolite cas:2466-09-3
ADP Metabolite cas:58-64-0
dephospho-CoA Metabolite cas:3633-59-8
ADP Metabolite cas:58-64-0
Coenzyme A Metabolite cas:64885-97-8
pyrophosphate Metabolite cas:2466-09-3
ATP Metabolite cas:1927-31-7
ATP Metabolite cas:1927-31-7
YDR531W GeneProduct sgd:S000002939
FSM1 GeneProduct sgd:S000004622
SIS2 GeneProduct sgd:S000001780
VHS3 GeneProduct sgd:S000005580
ALD3 GeneProduct sgd:S000004779
ALD2 GeneProduct sgd:S000004780
YGR277C GeneProduct sgd:S000003509
YDR196C GeneProduct sgd:S000002604
PAN5 GeneProduct sgd:S000001105
PAN6 GeneProduct sgd:S000001407
YKL088W GeneProduct sgd:S000001571
YIL083C GeneProduct sgd:S000001345
ECM31 GeneProduct sgd:S000000380