Transcription factors regulate miRNAs related to cardiac hypertrophy (WP1559)

Homo sapiens

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Transcription Factors that possibly regulate the expression of microRNAs related to cardiac hypertrophy. Interactions found by using TransMir. MicroRNAs are represented by a purple color and a rounded rectangle. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP1559 CPTAC Assay Portal].

Authors

Maartje Levels , Kristina Hanspers , Andika Tan , Egon Willighagen , Marvin Martens , and Eric Weitz

Activity

last edited

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

hypertrophic cardiomyopathy pathway

Cell Type Ontology

cardiac muscle cell

Participants
Query Drugst.One

Label Type Compact URI Comment
NFkB GeneProduct ncbigene:4790
NFkB GeneProduct ncbigene:4790
RAS GeneProduct ncbigene:5923
AKT1 GeneProduct ncbigene:207
Calcineurin GeneProduct ncbigene:5534
AKT1 GeneProduct ncbigene:207
MIR29A GeneProduct ensembl:ENSG00000284032
TGFbeta GeneProduct ncbigene:7040
MEF-2 GeneProduct ncbigene:50804
AKT2 GeneProduct ncbigene:208
STAT3 GeneProduct ncbigene:6774

References