Tryptophan metabolism (WP1126)

Canis familiaris

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This pathway describes the metabolism of tryptophan, an essential amino acid. Original pathway was converted from rat to human using ortholog information. Edited by Sebastien Burel

Authors

Egon Willighagen , Friederike Ehrhart , and Kristina Hanspers

Activity

last edited

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Cited In

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Organisms

Canis familiaris

Communities

Annotations

Pathway Ontology

tryptophan metabolic pathway

Participants

Label Type Compact URI Comment
Formylkynurenine Metabolite cas:1022-31-7 Formylkynurenine
4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate Metabolite hmdb:HMDB0004083
Acetyl-CoA Metabolite cas:72-89-9 Acetyl-CoA
Indole Metabolite cas:120-72-9
5-Methoxytryptamine Metabolite cas:608-07-1
5-Hydroxy-L-tryptophan Metabolite hmdb:HMDB0000472
L-Kynurenine Metabolite cas:343-65-7 L-Kynurenine
Melatonin Metabolite hmdb:HMDB0001389
5-Hydroxykynurenine Metabolite cas:484-78-6
Xanthurenic acid Metabolite hmdb:HMDB0000881
N-Methylserotonin Metabolite hmdb:HMDB0004369
Tryptamine Metabolite cas:61-54-1
5-Hydroxy-N-formylkynurenine Metabolite hmdb:HMDB0004086
4,6-Dihydroxyquinoline Metabolite hmdb:HMDB0004077
N-Acetylisatin Metabolite cas:574-17-4 N-Acetylisatin
L-Tryptophan Metabolite cas:73-22-3
Indole-3-acetamide Metabolite cas:879-37-8 Indole-3-acetamide
Acetoacetyl-CoA Metabolite kegg.compound:C00332
N-Methyltryptamine Metabolite chebi:28136
Crotonoyl-CoA Metabolite kegg.compound:C00877
5-(2'-Carboxyethyl)-4,6-Dihydroxypicolinate Metabolite hmdb:HMDB0006794
3-Indoleacetonitrile Metabolite cas:771-51-7 3-Indoleacetonitrile
5-Hydroxyindoleacetaldehyde Metabolite hmdb:HMDB0004073
2-Aminophenol Metabolite cas:95-55-6 2-Aminophenol
6-Hydroxymelatonin Metabolite cas:2208-41-5
Glutaryl-CoA Metabolite kegg.compound:C00527
N-Acetylserotonin Metabolite cas:1210-83-9 N-Acetylserotonin
UBR5 GeneProduct ncbigene:475055
IDO1 GeneProduct ncbigene:475574
CYP2E1 GeneProduct ncbigene:415128
RNF25 GeneProduct ncbigene:478912
GCDH GeneProduct ncbigene:476696 predicted
ALDH9A1 GeneProduct ncbigene:478991
PRMT1 GeneProduct ncbigene:476411
ALDH2 GeneProduct ncbigene:610941
ALDH1A2 GeneProduct ncbigene:478319
LOC100683688 GeneProduct ncbigene:100683688
CYP1A1 GeneProduct ncbigene:100686778
MDM2 GeneProduct ncbigene:403693
OGDH GeneProduct ncbigene:475499
MAOB GeneProduct ncbigene:403451
ALDH3A2 GeneProduct ncbigene:479518
MAOB GeneProduct ncbigene:403451
DDC GeneProduct ncbigene:606852
HSD17B10 GeneProduct ncbigene:480930
ALDH9A1 GeneProduct ncbigene:478991
CAT GeneProduct ncbigene:403474
UBE3A GeneProduct ncbigene:479010
HADH GeneProduct ncbigene:478506
ALDH3A2 GeneProduct ncbigene:479518
DDC GeneProduct ncbigene:606852
DDC GeneProduct ncbigene:606852
ALDH2 GeneProduct ncbigene:610941
MAOB GeneProduct ncbigene:403451
MDM2 GeneProduct ncbigene:403693
CYP7B1 GeneProduct ncbigene:486973
UBE3A GeneProduct ncbigene:479010
AADAT GeneProduct ncbigene:486059
ACAT1 GeneProduct ncbigene:489421
IDO1 GeneProduct ncbigene:475574
ALDH1A2 GeneProduct ncbigene:478319
KYNU GeneProduct ncbigene:483907
AFMID GeneProduct ncbigene:609011
CYP1B1 GeneProduct ncbigene:483038
AANAT GeneProduct ncbigene:483331
AOX1 GeneProduct ncbigene:608820
DHCR24 GeneProduct ncbigene:489573 predicted
AADAT GeneProduct ncbigene:486059
ACMSD GeneProduct ncbigene:476125
IDO1 GeneProduct ncbigene:475574
KYNU GeneProduct ncbigene:483907
CYP1A2 GeneProduct ncbigene:494010
CYP2C19 GeneProduct ncbigene:415122
WARS GeneProduct ncbigene:480435
CYP2A13 GeneProduct ncbigene:484494
CYP19A1 GeneProduct ncbigene:494003
PRMT1 GeneProduct ncbigene:476411
ALDH1A1 GeneProduct ncbigene:476323
CYP2J2 GeneProduct ncbigene:610195
HAAO GeneProduct ncbigene:611728
PRMT1 GeneProduct ncbigene:476411
ABP1 GeneProduct ncbigene:475536
RNF25 GeneProduct ncbigene:478912
MAOB GeneProduct ncbigene:403451
KYNU GeneProduct ncbigene:483907
MDM2 GeneProduct ncbigene:403693
ECHS1 GeneProduct ncbigene:480828
TDO2 GeneProduct ncbigene:475476
LOC612477 GeneProduct ncbigene:612477
GCDH GeneProduct ncbigene:476696 predicted
TPH1 GeneProduct ncbigene:611956
ALDH1A1 GeneProduct ncbigene:476323
LOC100683688 GeneProduct ncbigene:100683688

References