Angiotensin II signaling (acute) in thick ascending limbs (WP3887)

Rattus norvegicus

Authors

Agustin Gonzalez-Vicente , Alex Pico , Egon Willighagen , Kristina Hanspers , Susan Coort , Denise Slenter , and Martina Summer-Kutmon

Activity

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Cited In

• Unraveling the blood transcriptome after real-life exposure of Wistar-rats to PM2.5, PM1 and water-soluble metals in the ambient air (2020).

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Organisms

Rattus norvegicus

Communities

Renal Genomics Pathways

Annotations

Pathway Ontology

angiotensin signaling pathway renin-angiotensin cascade pathway signaling pathway

Disease Ontology

renal hypertension

Cell Type Ontology

kidney loop of Henle thick ascending limb epithelial cell

References

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2. Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors. Mukoyama M, Nakajima M, Horiuchi M, Sasamura H, Pratt RE, Dzau VJ. J Biol Chem. 1993 Nov 25;268(33):24539–42. PubMed Europe PMC Scholia
3. Cellular expression of angiotensin type-1 receptor mRNA in the kidney. Meister B, Lippoldt A, Bunnemann B, Inagami T, Ganten D, Fuxe K. Kidney Int. 1993 Aug;44(2):331–6. PubMed Europe PMC Scholia
4. Expression of type 1 angiotensin II receptor subtypes and angiotensin II-induced calcium mobilization along the rat nephron. Bouby N, Hus-Citharel A, Marchetti J, Bankir L, Corvol P, Llorens-Cortes C. J Am Soc Nephrol. 1997 Nov;8(11):1658–67. PubMed Europe PMC Scholia
5. ANG II controls Na(+)-K+(NH4+)-2Cl- cotransport via 20-HETE and PKC in medullary thick ascending limb. Amlal H, LeGoff C, Vernimmen C, Soleimani M, Paillard M, Bichara M. Am J Physiol. 1998 Apr;274(4):C1047-56. PubMed Europe PMC Scholia
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13. Superoxide stimulates NaCl absorption in the thick ascending limb via activation of protein kinase C. Silva GB, Ortiz PA, Hong NJ, Garvin JL. Hypertension. 2006 Sep;48(3):467–72. PubMed Europe PMC Scholia
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15. Losartan decreases vasopressin-mediated cAMP accumulation in the thick ascending limb of the loop of Henle in rats with congestive heart failure. Torp M, Brønd L, Hadrup N, Nielsen JB, Praetorius J, Nielsen S, et al. Acta Physiol (Oxf). 2007 Aug;190(4):339–50. PubMed Europe PMC Scholia
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18. Conversion of renal angiotensin II to angiotensin III is critical for AT2 receptor-mediated natriuresis in rats. Padia SH, Kemp BA, Howell NL, Fournie-Zaluski MC, Roques BP, Carey RM. Hypertension. 2008 Feb;51(2):460–5. PubMed Europe PMC Scholia
19. Angiotensin II type 2 receptors and nitric oxide sustain oxygenation in the clipped kidney of early Goldblatt hypertensive rats. Palm F, Connors SG, Mendonca M, Welch WJ, Wilcox CS. Hypertension. 2008 Feb;51(2):345–51. PubMed Europe PMC Scholia
20. Nitric oxide reduces flow-induced superoxide production via cGMP-dependent protein kinase in thick ascending limbs. Hong NJ, Garvin JL. Am J Physiol Renal Physiol. 2009 May;296(5):F1061-6. PubMed Europe PMC Scholia
21. Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs. Silva GB, Garvin JL. Am J Physiol Renal Physiol. 2009 Sep;297(3):F646-52. PubMed Europe PMC Scholia
22. Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb. Silva GB, Garvin JL. Am J Physiol Renal Physiol. 2010 Feb;298(2):F421-5. PubMed Europe PMC Scholia
23. PKC-alpha mediates flow-stimulated superoxide production in thick ascending limbs. Hong NJ, Silva GB, Garvin JL. Am J Physiol Renal Physiol. 2010 Apr;298(4):F885-91. PubMed Europe PMC Scholia
24. Angiotensin II stimulates thick ascending limb NO production via AT(2) receptors and Akt1-dependent nitric-oxide synthase 3 (NOS3) activation. Herrera M, Garvin JL. J Biol Chem. 2010 May 14;285(20):14932–40. PubMed Europe PMC Scholia
25. Angiotensin II stimulates thick ascending limb superoxide production via protein kinase C(α)-dependent NADPH oxidase activation. Herrera M, Silva GB, Garvin JL. J Biol Chem. 2010 Jul 9;285(28):21323–8. PubMed Europe PMC Scholia
26. Angiotensin II type 2 receptor-mediated inhibition of NaCl absorption is blunted in thick ascending limbs from Dahl salt-sensitive rats. Hong NJ, Garvin JL. Hypertension. 2012 Sep;60(3):765–9. PubMed Europe PMC Scholia
27. Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4. Massey KJ, Hong NJ, Garvin JL. Am J Physiol Cell Physiol. 2012 Oct 1;303(7):C781-9. PubMed Europe PMC Scholia
28. NADPH oxidase 4 mediates flow-induced superoxide production in thick ascending limbs. Hong NJ, Garvin JL. Am J Physiol Renal Physiol. 2012 Oct 15;303(8):F1151-6. PubMed Europe PMC Scholia
29. Angiotensin II stimulates basolateral 10-pS Cl channels in the thick ascending limb. Wu P, Wang M, Luan H, Li L, Wang L, Wang WH, et al. Hypertension. 2013 Jun;61(6):1211–7. PubMed Europe PMC Scholia
30. Angiotensin II inhibits ADH-stimulated cAMP: role on O2- and transport-related oxygen consumption in the loop of Henle. Silva GB, Juncos LI, Baigorria ST, Garcia NH. J Biol Regul Homeost Agents. 2013;27(2):569–78. PubMed Europe PMC Scholia
31. Angiotensin II stimulates basolateral 50-pS K channels in the thick ascending limb. Wang M, Luan H, Wu P, Fan L, Wang L, Duan X, et al. Am J Physiol Renal Physiol. 2014 Mar 1;306(5):F509-16. PubMed Europe PMC Scholia
32. Endogenous flow-induced superoxide stimulates Na/H exchange activity via PKC in thick ascending limbs. Hong NJ, Garvin JL. Am J Physiol Renal Physiol. 2014 Oct 1;307(7):F800-5. PubMed Europe PMC Scholia
33. Resveratrol increases nitric oxide production in the rat thick ascending limb via Ca2+/calmodulin. Gonzalez-Vicente A, Cabral PD, Garvin JL. PLoS One. 2014 Oct 14;9(10):e110487. PubMed Europe PMC Scholia
34. Endogenous flow-induced nitric oxide reduces superoxide-stimulated Na/H exchange activity via PKG in thick ascending limbs. Hong NJ, Garvin JL. Am J Physiol Renal Physiol. 2015 Mar 1;308(5):F444-9. PubMed Europe PMC Scholia
35. Angiotensin II stimulates superoxide production by nitric oxide synthase in thick ascending limbs. Gonzalez-Vicente A, Saikumar JH, Massey KJ, Hong NJ, Dominici FP, Carretero OA, et al. Physiol Rep. 2016 Feb;4(4):e12697. PubMed Europe PMC Scholia