One-carbon metabolism and related pathways (WP1770)
Mus musculus
Authors
Kristina Hanspers , Samuel Sklar , Thomas Kelder , Chris Evelo , Denise Slenter , Marvin Martens , Martina Summer-Kutmon , Egon Willighagen , and Eric WeitzActivity
Discuss this pathway
Check for ongoing discussions or start your own.
Cited In
- Proteomic profiling of salivary gland after nonviral gene transfer mediated by conventional plasmids and minicircles (2014).
- Podocyte-specific KLF6 primes proximal tubule CaMK1D signaling to attenuate diabetic kidney disease (2024).
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Organisms
Mus musculusCommunities
Annotations
Pathway Ontology
folate mediated one-carbon metabolic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| S-Adenosylhomocysteine | Metabolite | kegg.compound:C00021 | |
| Total Phospholipids | Metabolite | chebi:16247 | |
| L-Methionine | Metabolite | hmdb:HMDB0000696 | |
| 3-Sulfinoalanine | Metabolite | kegg.compound:C00606 | |
| L-Cysteine | Metabolite | kegg.compound:C00097 | |
| NADP | Metabolite | kegg.compound:C00006 | |
| Hypotaurine | Metabolite | kegg.compound:C00519 | |
| Glutathione (GSH) | Metabolite | kegg.compound:C00051 | |
| Tetrahydrofolic acid | Metabolite | kegg.compound:C00101 | |
| Phosphocholine | Metabolite | chebi:18132 | |
| Ethanolamine | Metabolite | kegg.compound:C00189 | |
| Taurocholic acid | Metabolite | kegg.compound:C05122 | |
| Glutathione disulfide (GSSG) | Metabolite | kegg.compound:C00127 | |
| 5,10-Methenyltetrahydrofolic acid | Metabolite | kegg.compound:C00445 | |
| Taurochenodesoxycholic acid | Metabolite | kegg.compound:C05465 | |
| Glutamate | Metabolite | kegg.compound:C00217 | |
| CDP-choline | Metabolite | kegg.compound:C00307 | |
| O-Phosphoethanolamine | Metabolite | kegg.compound:C00346 | |
| Phosphatidylethanolamine | Metabolite | kegg.compound:C00350 | |
| Dimethylglycine | Metabolite | kegg.compound:C01026 | |
| Betaine | Metabolite | kegg.compound:C00719 | |
| Phosphatidylcholines | Metabolite | cas:8002-43-5 | |
| L-Serine | Metabolite | kegg.compound:C00065 | |
| Taurine | Metabolite | kegg.compound:C00245 | |
| NADPH | Metabolite | kegg.compound:C00005 | |
| Sarcosine | Metabolite | kegg.compound:C00213 | |
| CDP-Ethanolamine | Metabolite | kegg.compound:C00570 | |
| 10-formyldihydrofolate | Metabolite | hmdb:HMDB0006485 | |
| 5-oxoproline | Metabolite | kegg.compound:C01879 | |
| 5-Methyltetrahydrofolic acid | Metabolite | kegg.compound:C00440 | |
| L-Cystathionine | Metabolite | kegg.compound:C02291 | |
| Folic acid | Metabolite | kegg.compound:C00504 | |
| S-Adenosylmethionine | Metabolite | kegg.compound:C00019 | |
| Homocysteine | Metabolite | kegg.compound:C05330 | |
| Glycine | Metabolite | kegg.compound:C00037 | |
| Choline | Metabolite | kegg.compound:C00114 | |
| gamma-Glutamylcysteine | Metabolite | kegg.compound:C00669 | |
| 2-oxobutanoate | Metabolite | chebi:16763 | |
| (S)-2-Aminobutanoate | Metabolite | chebi:35619 | |
| gamma-L-Glutamyl-L-2-aminobutyrate | Metabolite | pubchem.compound:7014903 | |
| Ophthalmate | Metabolite | pubchem.compound:7018721 | |
| Etnk2 | GeneProduct | ncbigene:214253 | |
| Gpx5 | GeneProduct | ncbigene:14780 | |
| Sod1 | GeneProduct | ncbigene:20655 | |
| Csad | GeneProduct | ncbigene:246277 | |
| Chpt1 | GeneProduct | ncbigene:212862 | |
| Dhfr | GeneProduct | ncbigene:13361 | |
| Pcyt1a | GeneProduct | ncbigene:13026 | |
| Mat2a | GeneProduct | ncbigene:232087 | |
| Gsr | GeneProduct | ncbigene:14782 | |
| Pcyt1b | GeneProduct | ncbigene:236899 | |
| Etnk1 | GeneProduct | ncbigene:75320 | |
| Cept1 | GeneProduct | ncbigene:99712 | |
| Sod3 | GeneProduct | ncbigene:20657 | |
| Mat1a | GeneProduct | ncbigene:11720 | |
| Gpx7 | GeneProduct | ncbigene:67305 | |
| Cth | GeneProduct | ncbigene:107869 | |
| Gss | GeneProduct | ncbigene:14854 | |
| Chdh | GeneProduct | ncbigene:218865 | |
| Dnmt3a | GeneProduct | ncbigene:13435 | |
| Bhmt2 | GeneProduct | ncbigene:64918 | |
| Mthfr | GeneProduct | ncbigene:17769 | |
| Dnm1 | GeneProduct | ncbigene:13429 | |
| Pld1 | GeneProduct | ncbigene:18805 | |
| Sod2 | GeneProduct | ncbigene:20656 | |
| Gpx6 | GeneProduct | ncbigene:75512 | |
| Chkb | GeneProduct | ncbigene:12651 | |
| Gad1 | GeneProduct | ncbigene:14415 | |
| Cdo1 | GeneProduct | ncbigene:12583 | |
| Gad2 | GeneProduct | ncbigene:14417 | |
| Gnmt | GeneProduct | ncbigene:14711 | |
| Bhmt | GeneProduct | ncbigene:12116 | |
| Shmt1 | GeneProduct | ncbigene:20425 | |
| Pcyt2 | GeneProduct | ncbigene:68671 | |
| Sardh | GeneProduct | ncbigene:192166 | |
| Gpx4 | GeneProduct | ncbigene:625249 | |
| Gpx2 | GeneProduct | ncbigene:14776 | |
| Gpx1 | GeneProduct | ncbigene:14775 | |
| Mtr | GeneProduct | ncbigene:238505 | |
| Gclm | GeneProduct | ncbigene:14630 | |
| Gpx3 | GeneProduct | ncbigene:14778 | |
| Ahcyl1 | GeneProduct | ncbigene:229709 | |
| Cbs | GeneProduct | ncbigene:12411 | |
| Dmgdh | GeneProduct | ncbigene:74129 | |
| Baat | GeneProduct | ncbigene:12012 | |
| Shmt2 | GeneProduct | ncbigene:108037 | |
| Chka | GeneProduct | ncbigene:12660 | |
| Tyms | GeneProduct | ncbigene:22171 | |
| Gclc | GeneProduct | ncbigene:14629 | |
| Pemt | GeneProduct | ncbigene:18618 | |
| Bcat1 | GeneProduct | ensembl:ENSMUSG00000030268 | |
| Gclc | GeneProduct | ensembl:ENSMUSG00000032350 | |
| Bcat2 | GeneProduct | ensembl:ENSMUSG00000030826 | |
| Gclm | GeneProduct | ensembl:ENSMUSG00000028124 | |
| Agxt2 | Protein | ensembl:ENSMUSG00000089678 | |
| Gss | Protein | ensembl:ENSMUSG00000027610 |