Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932)
Homo sapiens
Cell-matrix adhesions play important roles in biological processes such as cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. Focal adhesions are structures formed at the cell-extracellular matrix contact points, consisting of bundles of actin filaments anchored to trans-membrane receptors of the integrin family through a complex of multiple proteins. In addition to participating in the structural link between membrane receptors and the actin cytoskeleton, focal adhesions also contain signaling molecules, such as protein kinases and phosphatases, their substrates, and various adapter proteins. Integrin signaling is dependent on the non-receptor tyrosine kinase activities of the FAK and src proteins and the adaptor protein functions of FAK, src and Shc to initiate downstream signaling events. These signaling events results in the reorganization of the actin cytoskeleton, which is essential for changes in cell shape and motility, and gene expression. Source: [https://www.genome.jp/dbget-bin/www_bget?pathway+map04510 KEGG] Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP3932 CPTAC Assay Portal]
Authors
Kristina Hanspers , Denise Slenter , Eric Weitz , and Marvin MartensActivity
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Cited In
- Complete response to neoadjuvant chemoradiotherapy in rectal cancer is associated with RAS/AKT mutations and high tumour mutational burden (2021).
- Predictive models for stage and risk classification in head and neck squamous cell carcinoma (HNSCC) (2020).
- Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus–A Co-expression Network Based Analysis (2018).
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Organisms
Homo sapiensCommunities
CPTAC PancCanNetAnnotations
Pathway Ontology
mTOR signaling pathway cell adhesion signaling pathway signaling pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| NO | Metabolite | chebi:29120 | Added ID for Nitric oxide (1+), which makes more sense then NO(radical) |
| Insulin | Metabolite | chebi:5931 | |
| NOS2 | GeneProduct | ensembl:ENSG00000007171 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18126 |
| NOS3 | GeneProduct | ensembl:ENSG00000164867 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18127 |
| ITGA5 | GeneProduct | ensembl:ENSG00000161638 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16402 |
| TSC1 | GeneProduct | ensembl:ENSG00000165699 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64930 |
| PIK3CA | GeneProduct | ensembl:ENSG00000121879 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18706 |
| CSF3 | GeneProduct | ensembl:ENSG00000108342 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12985 |
| GRB2 | GeneProduct | ensembl:ENSG00000177885 | GRB2; growth factor receptor-bound protein 2Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14784 |
| JAK3 | GeneProduct | ensembl:ENSG00000105639 | CAV3; caveolin 3Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16453 |
| JAK2 | GeneProduct | ensembl:ENSG00000096968 | CAV2; caveolin 2Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16452 |
| EPO | GeneProduct | ensembl:ENSG00000130427 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13856 |
| COL4A2 | GeneProduct | ensembl:ENSG00000134871 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12827 |
| CHAD | GeneProduct | ensembl:ENSG00000136457 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12643 |
| ITGB7 | GeneProduct | ensembl:ENSG00000139626 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16421 |
| TNR | GeneProduct | ensembl:ENSG00000116147 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21960 |
| STK11 | GeneProduct | ensembl:ENSG00000118046 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20869 |
| COL11A2 | GeneProduct | ensembl:ENSG00000204248 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12815 |
| LAMB3 | GeneProduct | ensembl:ENSG00000196878 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16780 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15962 |
| CSH1 | GeneProduct | ensembl:ENSG00000136488 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14599 |
| COMP | GeneProduct | ensembl:ENSG00000105664 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12845 |
| ITGAE | GeneProduct | ensembl:ENSG00000083457 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16407 |
| COL1A2 | GeneProduct | ensembl:ENSG00000164692 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12843 |
| ITGB4 | GeneProduct | ensembl:ENSG00000132470 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:192897 |
| FN1 | GeneProduct | ensembl:ENSG00000115414 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14268 |
| ITGAX | GeneProduct | ensembl:ENSG00000140678 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16411 |
| ITGAD | GeneProduct | ensembl:ENSG00000156886 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:381924 |
| THBS2 | GeneProduct | ensembl:ENSG00000186340 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21826 |
| IL3RA | GeneProduct | ensembl:ENSG00000185291 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16188 |
| PIK3R1 | GeneProduct | ensembl:ENSG00000145675 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18708 |
| COL5A1 | GeneProduct | ensembl:ENSG00000130635 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12831 |
| AKT1 | GeneProduct | ensembl:ENSG00000142208 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11651 |
| RELN | GeneProduct | ensembl:ENSG00000189056 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19699 |
| PTK2 | GeneProduct | ensembl:ENSG00000169398 | DOCK1; dedicator of cyto-kinesisHomology Mapping from Mus musculus to Homo sapiens: Original ID = L:14083 |
| PIK3IP1 | GeneProduct | ensembl:ENSG00000100100 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:216505 |
| LAMC3 | GeneProduct | ensembl:ENSG00000050555 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23928 |
| IL2RB | GeneProduct | ensembl:ENSG00000100385 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16185 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15965 |
| LAMC2 | GeneProduct | ensembl:ENSG00000058085 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16782 |
| IFNAR1 | GeneProduct | ensembl:ENSG00000142166 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15975 |
| LAMB1 | GeneProduct | ensembl:ENSG00000091136 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16777 |
| ITGA7 | GeneProduct | ensembl:ENSG00000135424 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16404 |
| ITGB6 | GeneProduct | ensembl:ENSG00000115221 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16420 |
| ITGA2B | GeneProduct | ensembl:ENSG00000005961 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16399 |
| ITGA9 | GeneProduct | ensembl:ENSG00000144668 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:104099 |
| ITGA2 | GeneProduct | ensembl:ENSG00000164171 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16398 |
| ITGB2 | GeneProduct | ensembl:ENSG00000160255 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16414 |
| PIK3R2 | GeneProduct | ensembl:ENSG00000105647 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18709 |
| COL4A6 | GeneProduct | ensembl:ENSG00000197565 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:94216 |
| PELO | GeneProduct | ensembl:ENSG00000152684 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105083 |
| OSMR | GeneProduct | ensembl:ENSG00000145623 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18414 |
| DDIT4 | GeneProduct | ensembl:ENSG00000168209 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74747 |
| ITGA3 | GeneProduct | ensembl:ENSG00000005884 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16400 |
| TNC | GeneProduct | ensembl:ENSG00000041982 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21923 |
| COL5A2 | GeneProduct | ensembl:ENSG00000204262 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12832 |
| LAMA4 | GeneProduct | ensembl:ENSG00000112769 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16775 |
| ITGA8 | GeneProduct | ensembl:ENSG00000077943 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:241226 |
| COL4A1 | GeneProduct | ensembl:ENSG00000187498 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12826 |
| LAMA3 | GeneProduct | ensembl:ENSG00000053747 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000024421 |
| LAMC1 | GeneProduct | ensembl:ENSG00000135862 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226519 |
| LAMB2 | GeneProduct | ensembl:ENSG00000172037 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16779 |
| THBS4 | GeneProduct | ensembl:ENSG00000113296 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21828 |
| COL2A1 | GeneProduct | ensembl:ENSG00000139219 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12824 |
| JAK1 | GeneProduct | ensembl:ENSG00000162434 | CAV1; caveolin 1 caveolae protein 22kDHomology Mapping from Mus musculus to Homo sapiens: Original ID = L:16451 |
| PIK3CB | GeneProduct | ensembl:ENSG00000051382 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74769 |
| THBS3 | GeneProduct | ensembl:ENSG00000169231 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21827 |
| ITGA10 | GeneProduct | ensembl:ENSG00000143127 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = En:ENSMUSG00000090210 |
| ITGAV | GeneProduct | ensembl:ENSG00000138448 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = M:MGI:96608 |
| PRLR | GeneProduct | ensembl:ENSG00000113494 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19116 |
| IL7R | GeneProduct | ensembl:ENSG00000168685 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16197 |
| ITGA6 | GeneProduct | ensembl:ENSG00000091409 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16403 |
| LAMA5 | GeneProduct | ensembl:ENSG00000130702 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16776 |
| IL6R | GeneProduct | ensembl:ENSG00000160712 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16194 |
| ITGB1 | GeneProduct | ensembl:ENSG00000150093 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16412 |
| IBSP | GeneProduct | ensembl:ENSG00000029559 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15891 |
| COL6A2 | GeneProduct | ensembl:ENSG00000142173 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12834 |
| VWF | GeneProduct | ensembl:ENSG00000110799 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22371 |
| TNXB | GeneProduct | ensembl:ENSG00000168477 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:81877 |
| ITGB5 | GeneProduct | ensembl:ENSG00000082781 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16419 |
| TNN | GeneProduct | ensembl:ENSG00000120332 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:329278 |
| SPP1 | GeneProduct | ensembl:ENSG00000118785 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20750 |
| PTEN | GeneProduct | ensembl:ENSG00000171862 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19211 |
| LAMA2 | GeneProduct | ensembl:ENSG00000196569 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16773 |
| CSF3R | GeneProduct | ensembl:ENSG00000119535 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12986 |
| IL2RA | GeneProduct | ensembl:ENSG00000134460 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16184 |
| EPOR | GeneProduct | ensembl:ENSG00000187266 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13857 |
| COL3A1 | GeneProduct | ensembl:ENSG00000168542 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12825 |
| ITGAL | GeneProduct | ensembl:ENSG00000005844 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16408 |
| IL4R | GeneProduct | ensembl:ENSG00000077238 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16190 |
| LAMA1 | GeneProduct | ensembl:ENSG00000101680 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16772 |
| SOS1 | GeneProduct | ensembl:ENSG00000115904 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20662 |
| ITGB3 | GeneProduct | ensembl:ENSG00000259207 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16416 |
| TSC2 | GeneProduct | ensembl:ENSG00000103197 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22084 |
| PIK3CD | GeneProduct | ensembl:ENSG00000171608 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18707 |
| ITGB8 | GeneProduct | ensembl:ENSG00000105855 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320910 |
| VTN | GeneProduct | ensembl:ENSG00000109072 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22370 |
| THBS1 | GeneProduct | ensembl:ENSG00000137801 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21825 |
| AKT3 | GeneProduct | ensembl:ENSG00000117020 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:23797 |
| COL1A1 | GeneProduct | ensembl:ENSG00000108821 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12842 |
| COL11A1 | GeneProduct | ensembl:ENSG00000060718 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12814 |
| PIK3R4 | GeneProduct | ensembl:ENSG00000196455 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75669 |
| COL5A3 | GeneProduct | ensembl:ENSG00000080573 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53867 |
| IL2RG | GeneProduct | ensembl:ENSG00000147168 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16186 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15964 |
| IFNAR2 | GeneProduct | ensembl:ENSG00000159110 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15976 |
| COL4A4 | GeneProduct | ensembl:ENSG00000081052 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12829 |
| AKT2 | GeneProduct | ensembl:ENSG00000105221 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11652 |
| ITGA4 | GeneProduct | ensembl:ENSG00000115232 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16401 |
| GHR | GeneProduct | ensembl:ENSG00000112964 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14600 |
| ITGA11 | GeneProduct | ensembl:ENSG00000137809 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:319480 |
| PIK3R5 | GeneProduct | ensembl:ENSG00000141506 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:320207 |
| EFNA1 | GeneProduct | ensembl:ENSG00000169242 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13636 |
| FGF1 | GeneProduct | ensembl:ENSG00000113578 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14164 |
| FGF11 | GeneProduct | ensembl:ENSG00000161958 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14166 |
| FGF10 | GeneProduct | ensembl:ENSG00000070193 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14165 |
| EFNA2 | GeneProduct | ensembl:ENSG00000099617 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13637 |
| EGF | GeneProduct | ensembl:ENSG00000138798 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13645 |
| FGF12 | GeneProduct | ensembl:ENSG00000114279 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14167 |
| CSF1 | GeneProduct | ensembl:ENSG00000184371 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12977 |
| ANGPT4 | GeneProduct | ensembl:ENSG00000101280 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11602 |
| ANGPT2 | GeneProduct | ensembl:ENSG00000091879 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11601 |
| ANGPT1 | GeneProduct | ensembl:ENSG00000154188 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11600 |
| VEGFA | GeneProduct | ensembl:ENSG00000112715 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22339 |
| EFNA3 | GeneProduct | ensembl:ENSG00000143590 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13638 |
| EFNA4 | GeneProduct | ensembl:ENSG00000243364 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13639 |
| EFNA5 | GeneProduct | ensembl:ENSG00000184349 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13640 |
| FGF14 | GeneProduct | ensembl:ENSG00000102466 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14169 |
| FGF13 | GeneProduct | ensembl:ENSG00000129682 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14168 |
| FGF19 | GeneProduct | ensembl:ENSG00000162344 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14170 |
| FGF17 | GeneProduct | ensembl:ENSG00000158815 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14171 |
| FGF18 | GeneProduct | ensembl:ENSG00000156427 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14172 |
| FGF2 | GeneProduct | ensembl:ENSG00000138685 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14173 |
| FGF3 | GeneProduct | ensembl:ENSG00000186895 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14174 |
| FGF4 | GeneProduct | ensembl:ENSG00000075388 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14175 |
| FGF6 | GeneProduct | ensembl:ENSG00000111241 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14177 |
| FGF7 | GeneProduct | ensembl:ENSG00000140285 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14178 |
| FGF8 | GeneProduct | ensembl:ENSG00000107831 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14179 |
| FGF9 | GeneProduct | ensembl:ENSG00000102678 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14180 |
| VEGFD | GeneProduct | ensembl:ENSG00000165197 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14205 |
| HGF | GeneProduct | ensembl:ENSG00000019991 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15234 |
| IGF1 | GeneProduct | ensembl:ENSG00000017427 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16000 |
| INS | GeneProduct | ensembl:ENSG00000254647 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16333 |
| INS | GeneProduct | ensembl:ENSG00000254647 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16334 |
| KITLG | GeneProduct | ensembl:ENSG00000049130 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17311 |
| VEGFC | GeneProduct | ensembl:ENSG00000150630 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22341 |
| VEGFB | GeneProduct | ensembl:ENSG00000173511 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22340 |
| PDGFB | GeneProduct | ensembl:ENSG00000100311 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18591 |
| PGF | GeneProduct | ensembl:ENSG00000119630 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18654 |
| PDGFA | GeneProduct | ensembl:ENSG00000197461 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18590 |
| NGF | GeneProduct | ensembl:ENSG00000134259 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18049 |
| PDGFC | GeneProduct | ensembl:ENSG00000145431 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:54635 |
| FGF21 | GeneProduct | ensembl:ENSG00000105550 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56636 |
| FGF22 | GeneProduct | ensembl:ENSG00000070388 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67112 |
| PDGFD | GeneProduct | ensembl:ENSG00000170962 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:71785 |
| FGF20 | GeneProduct | ensembl:ENSG00000078579 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80857 |
| FGF16 | GeneProduct | ensembl:ENSG00000196468 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:80903 |
| FGFR2 | GeneProduct | ensembl:ENSG00000066468 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14183 |
| KDR | GeneProduct | ensembl:ENSG00000128052 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16542 |
| INSR | GeneProduct | ensembl:ENSG00000171105 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16337 |
| FGFR3 | GeneProduct | ensembl:ENSG00000068078 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14184 |
| IGF1R | GeneProduct | ensembl:ENSG00000140443 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16001 |
| KIT | GeneProduct | ensembl:ENSG00000157404 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16590 |
| FGFR1 | GeneProduct | ensembl:ENSG00000077782 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14182 |
| EPHA2 | GeneProduct | ensembl:ENSG00000142627 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13836 |
| EGFR | GeneProduct | ensembl:ENSG00000146648 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13649 |
| CSF1R | GeneProduct | ensembl:ENSG00000182578 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12978 |
| FGFR4 | GeneProduct | ensembl:ENSG00000160867 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14186 |
| FLT1 | GeneProduct | ensembl:ENSG00000102755 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14254 |
| FLT4 | GeneProduct | ensembl:ENSG00000037280 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14257 |
| NGFR | GeneProduct | ensembl:ENSG00000064300 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18053 |
| MET | GeneProduct | ensembl:ENSG00000105976 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17295 |
| PDGFRA | GeneProduct | ensembl:ENSG00000134853 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18595 |
| PDGFRB | GeneProduct | ensembl:ENSG00000113721 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18596 |
| TEK | GeneProduct | ensembl:ENSG00000120156 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21687 |
| AKT1S1 | GeneProduct | ensembl:ENSG00000204673 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67605 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15967 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15968 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15969 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15970 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15972 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15974 |
| IFNB1 | GeneProduct | ensembl:ENSG00000171855 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15977 |
| IL2 | GeneProduct | ensembl:ENSG00000109471 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16183 |
| OSM | GeneProduct | ensembl:ENSG00000099985 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18413 |
| PRL | GeneProduct | ensembl:ENSG00000172179 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19109 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:230396 |
| IFNA7 | GeneProduct | ensembl:ENSG00000214042 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:404549 |
| CHRM1 | GeneProduct | ensembl:ENSG00000168539 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12669 |
| LPAR1 | GeneProduct | ensembl:ENSG00000198121 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14745 |
| F2R | GeneProduct | ensembl:ENSG00000181104 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14062 |
| CHRM2 | GeneProduct | ensembl:ENSG00000181072 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:243764 |
| LPAR5 | GeneProduct | ensembl:ENSG00000184574 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:381810 |
| LPAR2 | GeneProduct | ensembl:ENSG00000064547 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53978 |
| LPAR3 | GeneProduct | ensembl:ENSG00000171517 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:65086 |
| LPAR6 | GeneProduct | ensembl:ENSG00000139679 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:67168 |
| LPAR4 | GeneProduct | ensembl:ENSG00000147145 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78134 |
| GNG5 | GeneProduct | ensembl:ENSG00000174021 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:100043507 |
| GNB2 | GeneProduct | ensembl:ENSG00000172354 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14693 |
| GNB1 | GeneProduct | ensembl:ENSG00000078369 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14688 |
| GNB4 | GeneProduct | ensembl:ENSG00000114450 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14696 |
| GNGT1 | GeneProduct | ensembl:ENSG00000127928 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14699 |
| GNG10 | GeneProduct | ensembl:ENSG00000242616 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14700 |
| GNG12 | GeneProduct | ensembl:ENSG00000172380 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14701 |
| GNB3 | GeneProduct | ensembl:ENSG00000111664 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14695 |
| GNG2 | GeneProduct | ensembl:ENSG00000186469 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14702 |
| GNG3 | GeneProduct | ensembl:ENSG00000162188 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14704 |
| GNG4 | GeneProduct | ensembl:ENSG00000168243 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14706 |
| GNG5 | GeneProduct | ensembl:ENSG00000174021 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14707 |
| GNG7 | GeneProduct | ensembl:ENSG00000176533 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14708 |
| GNG8 | GeneProduct | ensembl:ENSG00000167414 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14709 |
| GNGT2 | GeneProduct | ensembl:ENSG00000167083 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14710 |
| GNG13 | GeneProduct | ensembl:ENSG00000127588 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:64337 |
| GNG11 | GeneProduct | ensembl:ENSG00000127920 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:66066 |
| PIK3CG | GeneProduct | ensembl:ENSG00000105851 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:30955 |
| NRAS | GeneProduct | ensembl:ENSG00000213281 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18176 |
| KRAS | GeneProduct | ensembl:ENSG00000133703 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16653 |
| HRAS | GeneProduct | ensembl:ENSG00000174775 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15461 |
| STRADA | GeneProduct | ensembl:ENSG00000266173 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72149 |
| CAB39 | GeneProduct | ensembl:ENSG00000135932 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12283 |
| CAB39L | GeneProduct | ensembl:ENSG00000102547 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:69008 |
| PRKAA1 | GeneProduct | ensembl:ENSG00000132356 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:105787 |
| PRKAA2 | GeneProduct | ensembl:ENSG00000162409 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:108079 |
| MLST8 | GeneProduct | ensembl:ENSG00000167965 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56716 |
| RHEB | GeneProduct | ensembl:ENSG00000106615 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19744 |
| MTOR | GeneProduct | ensembl:ENSG00000198793 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56717 |
| RPTOR | GeneProduct | ensembl:ENSG00000141564 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74370 |
| HIF1A | GeneProduct | ensembl:ENSG00000100644 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15251 |
| ULK1 | GeneProduct | ensembl:ENSG00000177169 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22241 |
| CRTC2 | GeneProduct | ensembl:ENSG00000160741 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:74343 |
| CDC37 | GeneProduct | ensembl:ENSG00000105401 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12539 |
| HSP90AB1 | GeneProduct | ensembl:ENSG00000096384 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15516 |
| PHLPP1 | GeneProduct | ensembl:ENSG00000081913 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:98432 |
| TCL1A | GeneProduct | ensembl:ENSG00000100721 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21432 |
| PDPK1 | GeneProduct | ensembl:ENSG00000140992 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18607 |
| PPP2CB | GeneProduct | ensembl:ENSG00000104695 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19053 |
| PPP2CA | GeneProduct | ensembl:ENSG00000113575 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19052 |
| PPP2R5D | GeneProduct | ensembl:ENSG00000112640 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:21770 |
| PPP2R5B | GeneProduct | ensembl:ENSG00000068971 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:225849 |
| PPP2R2B | GeneProduct | ensembl:ENSG00000156475 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72930 |
| PPP2R1B | GeneProduct | ensembl:ENSG00000137713 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:73699 |
| PPP2R3A | GeneProduct | ensembl:ENSG00000073711 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:235542 |
| PPP2R5C | GeneProduct | ensembl:ENSG00000078304 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26931 |
| PPP2R5E | GeneProduct | ensembl:ENSG00000154001 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26932 |
| PPP2R2C | GeneProduct | ensembl:ENSG00000074211 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:269643 |
| PPP2R1A | GeneProduct | ensembl:ENSG00000105568 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:51792 |
| PPP2R2D | GeneProduct | ensembl:ENSG00000175470 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:52432 |
| PPP2R5A | GeneProduct | ensembl:ENSG00000066027 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:226849 |
| PPP2R3C | GeneProduct | ensembl:ENSG00000092020 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:59032 |
| HSP90AA1 | GeneProduct | ensembl:ENSG00000080824 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15519 |
| HSP90B1 | GeneProduct | ensembl:ENSG00000166598 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:22027 |
| PHLPP2 | GeneProduct | ensembl:ENSG00000040199 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:244650 |
| TCL1B | GeneProduct | ensembl:ENSG00000213231 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:27379 |
| TCL1B | GeneProduct | ensembl:ENSG00000213231 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:27380 |
| RAF1 | GeneProduct | ensembl:ENSG00000132155 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:110157 |
| MAP2K2 | GeneProduct | ensembl:ENSG00000126934 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26396 |
| MAP2K1 | GeneProduct | ensembl:ENSG00000169032 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26395 |
| MAPK1 | GeneProduct | ensembl:ENSG00000100030 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26413 |
| MAPK3 | GeneProduct | ensembl:ENSG00000102882 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26417 |
| GSK3B | GeneProduct | ensembl:ENSG00000082701 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56637 |
| FOXO3 | GeneProduct | ensembl:ENSG00000118689 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56484 |
| FOXO1 | GeneProduct | ensembl:ENSG00000150907 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:56458 |
| IKBKB | GeneProduct | ensembl:ENSG00000104365 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16150 |
| BAD | GeneProduct | ensembl:ENSG00000002330 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12015 |
| CASP9 | GeneProduct | ensembl:ENSG00000132906 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12371 |
| MDM2 | GeneProduct | ensembl:ENSG00000135679 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17246 |
| IKBKG | GeneProduct | ensembl:ENSG00000269335 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16151 |
| CDKN1B | GeneProduct | ensembl:ENSG00000111276 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12576 |
| CDKN1A | GeneProduct | ensembl:ENSG00000124762 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12575 |
| ATF2 | GeneProduct | ensembl:ENSG00000115966 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11909 |
| CREB3 | GeneProduct | ensembl:ENSG00000107175 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12913 |
| CREB1 | GeneProduct | ensembl:ENSG00000118260 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12912 |
| ATF4 | GeneProduct | ensembl:ENSG00000128272 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:11911 |
| CREB3L2 | GeneProduct | ensembl:ENSG00000182158 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208647 |
| CREB3L3 | GeneProduct | ensembl:ENSG00000060566 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:208677 |
| ATF6B | GeneProduct | ensembl:ENSG00000213676 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:12915 |
| CREB3L1 | GeneProduct | ensembl:ENSG00000157613 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26427 |
| CREB3L4 | GeneProduct | ensembl:ENSG00000143578 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:78284 |
| CREB5 | GeneProduct | ensembl:ENSG00000146592 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:231991 |
| TBC1D1 | GeneProduct | ensembl:ENSG00000065882 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:57915 |
| RAB8A | GeneProduct | ensembl:ENSG00000167461 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:17274 |
| RAB2A | GeneProduct | ensembl:ENSG00000104388 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:59021 |
| RAB10 | GeneProduct | ensembl:ENSG00000084733 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19325 |
| RAB11B | GeneProduct | ensembl:ENSG00000185236 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19326 |
| RAB14 | GeneProduct | ensembl:ENSG00000119396 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:68365 |
| SLC2A4 | GeneProduct | ensembl:ENSG00000181856 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20528 |
| SLC2A1 | GeneProduct | ensembl:ENSG00000117394 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20525 |
| SLC2A3 | GeneProduct | ensembl:ENSG00000059804 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20527 |
| SLC2A2 | GeneProduct | ensembl:ENSG00000163581 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20526 |
| PPARGC1A | GeneProduct | ensembl:ENSG00000109819 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:19017 |
| GYS1 | GeneProduct | ensembl:ENSG00000104812 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:14936 |
| GYS2 | GeneProduct | ensembl:ENSG00000111713 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:232493 |
| PFKFB2 | GeneProduct | ensembl:ENSG00000123836 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18640 |
| PFKFB1 | GeneProduct | ensembl:ENSG00000158571 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18639 |
| PFKFB3 | GeneProduct | ensembl:ENSG00000170525 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:170768 |
| PFKFB4 | GeneProduct | ensembl:ENSG00000114268 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:270198 |
| LIPE | GeneProduct | ensembl:ENSG00000079435 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16890 |
| SREBF1 | GeneProduct | ensembl:ENSG00000072310 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20787 |
| FOXA1 | GeneProduct | ensembl:ENSG00000129514 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15375 |
| ACACA | GeneProduct | ensembl:ENSG00000278540 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:107476 |
| ELAVL1 | GeneProduct | ensembl:ENSG00000066044 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:15568 |
| NOS1 | GeneProduct | ensembl:ENSG00000089250 | SOS1; son of sevenless homolog 1 (Drosophila)Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18125 |
| EPAS1 | GeneProduct | ensembl:ENSG00000116016 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13819 |
| HIF3A | GeneProduct | ensembl:ENSG00000124440 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:53417 |
| RPS6KB2 | GeneProduct | ensembl:ENSG00000175634 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:58988 |
| EIF4EBP1 | GeneProduct | ensembl:ENSG00000187840 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13685 |
| EIF4B | GeneProduct | ensembl:ENSG00000063046 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:75705 |
| RPS6KB1 | GeneProduct | ensembl:ENSG00000108443 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:72508 |
| RPS6 | GeneProduct | ensembl:ENSG00000137154 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:20104 |
| EIF4E | GeneProduct | ensembl:ENSG00000151247 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:13684 |
| EIF4E2 | GeneProduct | ensembl:ENSG00000135930 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:26987 |
| EIF4E1B | GeneProduct | ensembl:ENSG00000175766 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:218268 |
| PIK3C2B | GeneProduct | ensembl:ENSG00000133056 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:240752 |
| PIK3C2A | GeneProduct | ensembl:ENSG00000011405 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:18704 |
| IRS1 | GeneProduct | ensembl:ENSG00000169047 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16367 |
| IRS4 | GeneProduct | ensembl:ENSG00000133124 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:16370 |
| IRS2 | GeneProduct | ensembl:ENSG00000185950 | Homology Mapping from Mus musculus to Homo sapiens: Original ID = L:384783 |
References
- The PI3K-PDK1 connection: more than just a road to PKB. Vanhaesebroeck B, Alessi DR. Biochem J. 2000 Mar 15;346 Pt 3(Pt 3):561–76. PubMed Europe PMC Scholia
- Rho GTPases: signaling, migration, and invasion. Schmitz AA, Govek EE, Böttner B, Van Aelst L. Exp Cell Res. 2000 Nov 25;261(1):1–12. PubMed Europe PMC Scholia
- Paxillin and focal adhesion signalling. Turner CE. Nat Cell Biol. 2000 Dec;2(12):E231-6. PubMed Europe PMC Scholia
- Focal adhesions: structure and dynamics. Petit V, Thiery JP. Biol Cell. 2000 Oct;92(7):477–94. PubMed Europe PMC Scholia
- Fibronectin, integrins, and growth control. Danen EH, Yamada KM. J Cell Physiol. 2001 Oct;189(1):1–13. PubMed Europe PMC Scholia
- The protein kinase B/Akt signalling pathway in human malignancy. Nicholson KM, Anderson NG. Cell Signal. 2002 May;14(5):381–95. PubMed Europe PMC Scholia
- Get a ligand, get a life: integrins, signaling and cell survival. Stupack DG, Cheresh DA. J Cell Sci. 2002 Oct 1;115(Pt 19):3729–38. PubMed Europe PMC Scholia
- Focal adhesion kinase: the first ten years. Parsons JT. J Cell Sci. 2003 Apr 15;116(Pt 8):1409–16. PubMed Europe PMC Scholia
- Interactions between growth factor receptors and adhesion molecules: breaking the rules. Comoglio PM, Boccaccio C, Trusolino L. Curr Opin Cell Biol. 2003 Oct;15(5):565–71. PubMed Europe PMC Scholia
- Rho and Rac take center stage. Burridge K, Wennerberg K. Cell. 2004 Jan 23;116(2):167–79. PubMed Europe PMC Scholia
- Integrins: structure and signaling. Berman AE, Kozlova NI, Morozevich GE. Biochemistry (Mosc). 2003 Dec;68(12):1284–99. PubMed Europe PMC Scholia
- The mechanism of action of the tumour suppressor gene PTEN. Hlobilková A, Knillová J, Bártek J, Lukás J, Kolár Z. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2003 Nov;147(1):19–25. PubMed Europe PMC Scholia
- Regulation of E-cadherin expression and beta-catenin/Tcf transcriptional activity by the integrin-linked kinase. Oloumi A, McPhee T, Dedhar S. Biochim Biophys Acta. 2004 Apr 1;1691(1):1–15. PubMed Europe PMC Scholia
- Multiple connections link FAK to cell motility and invasion. Schlaepfer DD, Mitra SK. Curr Opin Genet Dev. 2004 Feb;14(1):92–101. PubMed Europe PMC Scholia
- Mitogenic signal transduction by integrin- and growth factor receptor-mediated pathways. Lee JW, Juliano R. Mol Cells. 2004 Apr 30;17(2):188–202. PubMed Europe PMC Scholia
- Integrin signalling during tumour progression. Guo W, Giancotti FG. Nat Rev Mol Cell Biol. 2004 Oct;5(10):816–26. PubMed Europe PMC Scholia
- Focal adhesion kinase: in command and control of cell motility. Mitra SK, Hanson DA, Schlaepfer DD. Nat Rev Mol Cell Biol. 2005 Jan;6(1):56–68. PubMed Europe PMC Scholia