Cell differentiation - index (WP2029)
miRNAs regulation of differentiation of numerous cell types. This diagram shows progressive commitment and subsequent differentiation of various lineages from pluripotent stem cells. Some examples of the influence by miRNAs on specific cell fates are shown. The pathway is based on [https://www.ncbi.nlm.nih.gov/pubmed/20621048 Fig 2 from Ivey and Srivastava]. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP2029 CPTAC Assay Portal]
AuthorsSamuel Sklar , Kristina Hanspers , Martijn Van Iersel , Alex Pico , Jonathan Mélius , Martina Summer-Kutmon , Denise Slenter , Eric Weitz , and Egon Willighagen
Discuss this pathway
Check for ongoing discussions or start your own.
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Pathway Ontologysignaling pathway pertinent to development
- MicroRNAs as regulators of differentiation and cell fate decisions. Ivey KN, Srivastava D. Cell Stem Cell. 2010 Jul 2;7(1):36–41. PubMed Europe PMC Scholia