Biogenic amine synthesis (WP125)

Drosophila melanogaster

Biogenic amines are one of two broad classes of classical neurotransmitters (the other being amino acids) and include: acetylcholine, serotonin, histamine, and the catecholamines epinephrine, norepinephrine, and dopamine. Source:


Alex Pico , Thomas Kelder , Egon Willighagen , Christine Chichester , Martina Summer-Kutmon , Krasin , Elisson nl , Eric Weitz , and Kristina Hanspers


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Drosophila melanogaster



Pathway Ontology

biogenic amine biosynthetic pathway


Label Type Compact URI Comment
Epinephrine Metabolite hmdb:HMDB00068
Dopamine Metabolite hmdb:HMDB00073
Tyrosine Metabolite chebi:17895
Norepinephrine Metabolite hmdb:HMDB00216
Histidine Metabolite hmdb:HMDB00177
GABA Metabolite chebi:16865
Phenylalanine Metabolite chebi:17295
Glutamate Metabolite chebi:14321
Choline Metabolite hmdb:HMDB00097
Acetylserotonin Metabolite hmdb:HMDB01238
Histamine Metabolite hmdb:HMDB00870
L-Dopa Metabolite hmdb:HMDB00181
Acetylcholine Metabolite hmdb:HMDB00895
Tryptophan Metabolite hmdb:HMDB00929
Melatonin Metabolite hmdb:HMDB01389
Serotonin Metabolite hmdb:HMDB00259
5-Hydroxy-L-tryptophan Metabolite hmdb:HMDB00472
ACHE GeneProduct ensembl:ENSG00000087085
Ddc GeneProduct ncbigene:35190
Trh GeneProduct ncbigene:38121
PNMT GeneProduct ensembl:ENSG00000141744
Ddc GeneProduct ncbigene:35190
Hn GeneProduct ncbigene:38871
ple GeneProduct ncbigene:38746
Tbh GeneProduct ncbigene:31718
Hdc GeneProduct ncbigene:36076
AANAT GeneProduct ensembl:ENSG00000129673
GAD2 GeneProduct ensembl:ENSG00000136750
MAOA GeneProduct ensembl:ENSG00000189221
ASMT GeneProduct ensembl:ENSG00000196433
Ddc GeneProduct ncbigene:35190
MAOA GeneProduct ensembl:ENSG00000189221
Cha GeneProduct ncbigene:42249
Gad1 GeneProduct ncbigene:38484
COMT GeneProduct ncbigene:47091