GPCRs, class C metabotropic glutamate, pheromone (WP501)

Homo sapiens

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This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.

Authors

Nathan Salomonis , Alex Pico , Bruce Conklin , Kristina Hanspers , Egon Willighagen , and Eric Weitz

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

G protein mediated signaling pathway

Participants
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Label Type Compact URI Comment
GRM1 GeneProduct ncbigene:2911
GRM5 GeneProduct ncbigene:2915
GRM2 GeneProduct ncbigene:2912
GRM3 GeneProduct ncbigene:2913
GRM8 GeneProduct ncbigene:2918
GRM4 GeneProduct ncbigene:2914
GRM7 GeneProduct ncbigene:2917
GRM6 GeneProduct ncbigene:2916
CASR GeneProduct ncbigene:846
GABBR1 GeneProduct ncbigene:2550
GPR51 GeneProduct ncbigene:9568
GPRC5D GeneProduct ncbigene:55507
GPRC5C GeneProduct ncbigene:55890
GPRC5B GeneProduct ncbigene:51704
GPRC5A GeneProduct ncbigene:9052

References

  1. GPCRDB: an information system for G protein-coupled receptors. Horn F, Weare J, Beukers MW, Hörsch S, Bairoch A, Chen W, et al. Nucleic Acids Res. 1998 Jan 1;26(1):275–9. PubMed Europe PMC Scholia
  2. Classifying G-protein coupled receptors with support vector machines. Karchin R, Karplus K, Haussler D. Bioinformatics. 2002 Jan;18(1):147–59. PubMed Europe PMC Scholia