Pyruvate dehydrogenase pathway (WP214)
Saccharomyces cerevisiae
Pyruvate dehydrogenase is a multiple enzyme complex that catalyzes the production of acetyl-CoA from pyruvate produced by glycolysis. The final step re-oxidizes the lipoyl group of dihydrolipoamide to form lipoamide and NADH.
Authors
Jessica Heckman , Daniela Digles , Egon Willighagen , Max Van Son , Eric Weitz , and Alex PicoActivity
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Organisms
Saccharomyces cerevisiaeCommunities
Annotations
Pathway Ontology
pyruvate metabolic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| NAD | Metabolite | chebi:13389 | |
| S-Acetyldihydrolipoamide | Metabolite | hmdb:HMDB0001526 | |
| pyruvate | Metabolite | chebi:15361 | |
| Coenzyme A | Metabolite | cas:64885-97-8 | |
| NADH | Metabolite | cas:53-84-9 | |
| lipoamide | Metabolite | cas:940-69-2 | |
| lipoamide | Metabolite | cas:940-69-2 | |
| acetyl-CoA | Metabolite | cas:72-89-9 | |
| dihydrolipoamide | Metabolite | cas:3884-47-7 | |
| PDA1 | GeneProduct | sgd:S000000980 | |
| PDB1 | GeneProduct | sgd:S000000425 | |
| LPD1 | GeneProduct | sgd:S000001876 | |
| LAT1 | GeneProduct | sgd:S000005015 |