Equilibrium signaling pathway of differentiated cells (WP3653)
Equilibrium signalling pathway for maintenance of progenitor cells in the lymph gland which is also affected by hedgehog protein niche signaling. Nup98 and Bip1 proteins both necessary for Pvr gene expression. Pvr/STAT92E complex activates Adgf-A to break down adenosine. Break down allows for proper maintenance of progenitor cells in equilibrium signalling. Niche signalling includes the expression of hedgehog by posterior signaling center also promoting progenitor maintenance. This pathway is based on figure 7 from Mondal et al.
AuthorsAAR&Co , Susan Coort , Kristina Hanspers , and Eric Weitz
Discuss this pathway
Check for ongoing discussions or start your own.
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Pathway Ontologyregulatory pathway signaling pathway
- Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors. Mondal BC, Shim J, Evans CJ, Banerjee U. Elife. 2014 Sep 8;3:e03626. PubMed Europe PMC Scholia