Steroid biosynthesis (WP496)

Homo sapiens

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Steroidogenesis is the biological process by which steroids are generated from cholesterol and transformed into other steroids. Proteins on this pathway have targeted assays available via the [https://assays.cancer.gov/available_assays?wp_id=WP496 CPTAC Assay Portal].

Authors

Andrew Kwa , Martijn Van Iersel , Kristina Hanspers , Alex Pico , Anatolymikutin , Egon Willighagen , Martina Summer-Kutmon , Denise Slenter , Eric Weitz , and Finterly Hu

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

Annotations

Pathway Ontology

steroid hormone biosynthetic pathway

Participants
Query Drugst.One

Label Type Compact URI Comment
Dehydroepiandrosterone Metabolite cas:53-43-0
Estradiol Metabolite cas:57-91-0
Progesterone Metabolite cas:57-83-0
Androstenediol Metabolite hmdb:HMDB0005849
Dihydrotestosterone Metabolite hmdb:HMDB0002961
Testosterone Metabolite cas:58-22-0
17-alpha-OH-pregnenolone Metabolite hmdb:HMDB0000363
Estrone Metabolite cas:53-16-7
Pregnenolone Metabolite cas:145-13-1
17-alpha-OH-progesterone Metabolite hmdb:HMDB0000374
Cholesterol Metabolite cas:57-88-5
Androstenedione Metabolite cas:63-05-8
HSD17B4 GeneProduct ncbigene:3295
HSD3B1 GeneProduct ncbigene:3283
Steroid 19-hydroxylase GeneProduct ensembl:ENSG00000120054
HSD17B2 GeneProduct ncbigene:3294
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
Hydroxyprogesterone aldolase GeneProduct eccode:4.1.2.30
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
F13B GeneProduct ncbigene:2165
HSD3B2 GeneProduct ncbigene:3284
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
CYP17A1 GeneProduct ncbigene:1586
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
CYP17A1 GeneProduct ncbigene:1586
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
HSD3B2 GeneProduct ncbigene:3284
HSD3B2 GeneProduct ncbigene:3284
HSD17B1 GeneProduct ncbigene:3292
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
HSD17B3 GeneProduct ncbigene:3293
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
HSD17B7 GeneProduct ncbigene:51478
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
HSD3B2 GeneProduct ncbigene:3284
Hydroxyprogesterone aldolase GeneProduct eccode:4.1.2.30
HSD3B1 GeneProduct ncbigene:3283
HSD3B1 GeneProduct ncbigene:3283
Steroid 19-hydroxylase GeneProduct ensembl:ENSG00000120054

References

  1. Diagram of the pathways of human steroidogenesis. Häggström M, Richfield D. Wiki J Med [Internet]. 2014;1(1). Available from: http://dx.doi.org/10.15347/wjm/2014.005 DOI Scholia