Hypoxia-dependent proliferation of myoblasts (WP5024)

Mus musculus

Molecular mechanisms involved in myogenic proliferation during hypoxia. Black arrow: activation of the signaling pathway/ protein/ molecule. Blunt red arrow: inhibition of the signaling pathway/protein/ molecule.


Maximilian Saller , Laurent Winckers , Lauren J. Dupuis , Eric Weitz , and Kristina Hanspers


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Mus musculus



Cell Type Ontology


Pathway Ontology

signaling pathway phosphatidylinositol 3-kinase-Akt signaling pathway


Label Type Compact URI Comment
VEGF GeneProduct ncbigene:22339
MSTN GeneProduct ncbigene:17700
Trim63 GeneProduct ncbigene:433766
MYOD1 GeneProduct ncbigene:17927
TSC2 GeneProduct ncbigene:22084
HGF GeneProduct ncbigene:15234
Fbxo32 GeneProduct ncbigene:67731
MYF5 GeneProduct ncbigene:17877
TSC1 GeneProduct ncbigene:64930
AKT GeneProduct ncbigene:11651
Smad3 GeneProduct ncbigene:17127
IGF1 GeneProduct ncbigene:16000
DDIT44 GeneProduct ncbigene:74747
RHEB GeneProduct ncbigene:19744
FGF GeneProduct ncbigene:14164
MTOR1 GeneProduct ncbigene:56717
Smad2 GeneProduct ncbigene:17126
MYOG GeneProduct ncbigene:17928
Calcitriol Protein uniprot:P70160


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