HIF1A and PPARG regulation of glycolysis (WP2456)

Homo sapiens

Hypoxia-inducible factor 1A and peroxisome proliferator activated receptor gamma play a role in regulating glycolysis. This pathway is part the [https://assays.cancer.gov/available_assays?wp_id=WP2456 CPTAC Assay Portal].


M Aguirre , Jonathan Mélius , Chris Evelo , Kristina Hanspers , Friederike Ehrhart , Alex Pico , and Finterly Hu


last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.


Homo sapiens



Pathway Ontology

regulatory pathway glycolysis/gluconeogenesis pathway


Label Type Compact URI Comment
Glyceraldehyde-3-phosphate Metabolite kegg.compound:C00118
Pyruvate Metabolite kegg.compound:C00022
Fructose-1,6-biphosphate Metabolite kegg.compound:C05378
Dihydroxyacetonephosphate Metabolite kegg.compound:C00111
Lactate Metabolite kegg.compound:C00186
Glycerol-3-phosphate Metabolite kegg.compound:C00093
Lysophosphatidate Metabolite kegg.compound:C00681
Triacylglycerol Metabolite kegg.compound:C00422
Diacylglycerol Metabolite kegg.compound:C00165
Glucose Metabolite kegg.compound:C00031
GAPDH GeneProduct ensembl:ENSG00000111640
LDHA GeneProduct ensembl:ENSG00000134333
TPI1 GeneProduct ensembl:ENSG00000111669
GPD1 GeneProduct ensembl:ENSG00000167588
GPAT3 GeneProduct ensembl:ENSG00000138678
SLC2A1 GeneProduct ensembl:ENSG00000117394
PPARG GeneProduct ensembl:ENSG00000132170
HIF1A GeneProduct ensembl:ENSG00000100644
HIF1A GeneProduct ensembl:ENSG00000100644