Oxidative damage response (WP1496)

Mus musculus

This pathway shows how tissue is damaged when oxygen levels are not balanced and become too high.


Samuel Sklar , Daniela Digles , Kristina Hanspers , Egon Willighagen , Martina Summer-Kutmon , and Eric Weitz


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Mus musculus



Pathway Ontology

oxidative stress response pathway


Label Type Compact URI Comment
Pcna GeneProduct ncbigene:18538
C1qg GeneProduct ncbigene:12262
Cdkn1c GeneProduct ncbigene:12577
C1qb GeneProduct ncbigene:12260
C5r1 GeneProduct ncbigene:12273
Tnfrsf1b GeneProduct ncbigene:21938
Hc GeneProduct ncbigene:15139
Traf3 GeneProduct ncbigene:22031
Bcl2 GeneProduct ncbigene:12043
Cr2 GeneProduct ncbigene:12902
Bad GeneProduct ncbigene:12015
Apaf1 GeneProduct ncbigene:11783
Map3k9 GeneProduct ncbigene:338372
Mapk13 GeneProduct ncbigene:26415
Cdc42 GeneProduct ncbigene:12540
Traf2 GeneProduct ncbigene:22030
C4 GeneProduct ncbigene:12268
Cdkn1a GeneProduct ncbigene:12575
Cyct GeneProduct ncbigene:13067
C1s GeneProduct ncbigene:50908
C1r GeneProduct ncbigene:50909
Ttrap GeneProduct ncbigene:56196
Cycs GeneProduct ncbigene:13063 Rel,Nup93,Nrf1,Them2,Syap1,Zfp259,2700059L22Rik,,Cotl1
Tnk2 GeneProduct ncbigene:51789
C3ar1 GeneProduct ncbigene:12267
Map2k6 GeneProduct ncbigene:26398 Xbp1,Mapk10,Klhl8,Mapk10
Bag4 GeneProduct ncbigene:67384
C2 GeneProduct ncbigene:12263
Cdkn1b GeneProduct ncbigene:12576
Traf1 GeneProduct ncbigene:22029
Mapk12 GeneProduct ncbigene:18037
Nfkb1 GeneProduct ncbigene:18033
Tnf GeneProduct ncbigene:21926
Gadd45a GeneProduct ncbigene:13197
Map3k1 GeneProduct ncbigene:26401
Mapk14 GeneProduct ncbigene:26414 Map2k4,Nlk,Fos,Fzd7,Jund1,ORF19,Map2k4,Dhodh,Map3k7,Dvl3,Eda,Rac1,Jup,Mllt4,Mink1,Myef2,Dusp10,Rala,Etv6,Frk,Wee1,Rexo1
Traf6 GeneProduct ncbigene:22034
C1qa GeneProduct ncbigene:12259
Casp3 GeneProduct ncbigene:12367
Bak1 GeneProduct ncbigene:12018
Casp9 GeneProduct ncbigene:12371