TCA cycle (WP490)

Saccharomyces cerevisiae

Based on Glycolysis and Gluconeogenesis Pathways at SGD and on Kruckeberg, AL and Dickinson, JR (2004) Carbon Metabolism in The Metabolism and Molecular Physiology of Saccharomyces cerevisiae, Dickinson, JR and Schweizer, M, eds, CRC Press.


Kdahlquist , Alex Pico , Kristina Hanspers , Thomas Kelder , Daniela Digles , Egon Willighagen , Martina Summer-Kutmon , Denise Slenter , Eric Weitz , and Lars Willighagen


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Saccharomyces cerevisiae



Pathway Ontology

citric acid cycle pathway


Label Type Compact URI Comment
alpha-ketoglutarate Metabolite hmdb:HMDB0000208
Fumarate Metabolite hmdb:HMDB0000134
Citrate Metabolite chemspider:29081
Glyoxylate Metabolite hmdb:HMDB0000119
Acetyl-CoA Metabolite cas:72-89-9
Isocitrate Metabolite cas:320-77-4
Malate Metabolite cas:6915-15-7
Succinyl-CoA Metabolite cas:604-98-8
Malate Metabolite cas:6915-15-7
Succinate Metabolite hmdb:HMDB0000254
Pyruvate Metabolite hmdb:HMDB0000243
Oxaloacetate Metabolite hmdb:HMDB0000223
Oxaloacetate Metabolite hmdb:HMDB0000223
Pyruvate Metabolite hmdb:HMDB0000243
Acetyl-CoA Metabolite cas:72-89-9
CIT3 GeneProduct ensembl:YPR001W
PDB1 GeneProduct ensembl:YBR221C
KGD1 GeneProduct ensembl:YIL125W
SDH4 GeneProduct ensembl:YDR178W
MDH2 GeneProduct ensembl:YOL126C
PYC2 GeneProduct ensembl:YBR218C
IDH2 GeneProduct ensembl:YOR136W
LAT1 GeneProduct ensembl:YNL071W
FUM1 GeneProduct ensembl:YPL262W
LPD1 GeneProduct ensembl:YFL018C
MAE1 GeneProduct ensembl:YKL029C
DAL7 GeneProduct ensembl:YIR031C
PDX1 GeneProduct ensembl:YGR193C
LPD1 GeneProduct ensembl:YFL018C
KGD2 GeneProduct ensembl:YDR148C
CIT1 GeneProduct ensembl:YNR001C
CIT2 GeneProduct ensembl:YCR005C
IDP1 GeneProduct ensembl:YDL066W
SDH3 GeneProduct ensembl:YKL141W
ACO2 GeneProduct ensembl:YJL200C
MDH1 GeneProduct ensembl:YKL085W
IDP2 GeneProduct ensembl:YLR174W
PDA1 GeneProduct ensembl:YER178W
LSC1 GeneProduct ensembl:YOR142W
ICL1 GeneProduct ensembl:YER065C peroxisome
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SDH1 GeneProduct ensembl:YKL148C
IDH1 GeneProduct ensembl:YNL037C
MDH3 GeneProduct ensembl:YDL078C
SDH2 GeneProduct ensembl:YLL041C
ACO1 GeneProduct ensembl:YLR304C
MLS1 GeneProduct ensembl:YNL117W peroxisome
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PYC1 GeneProduct ensembl:YGL062W
LSC2 GeneProduct ensembl:YGR244C


  1. Metabolism and Molecular Physiology of Saccharomyces Cerevisiae, 2nd Edition [Internet]. Dickinson JR, Schweizer M. CRC Press; 2004. 480 p. Available from: OpenLibrary Worldcat