Fehrhart

Glycolysis and gluconeogenesis

Nuclear receptors meta-pathway

RAS and bradykinin pathways in COVID-19

16p11.2 proximal deletion syndrome

Serotonin HTR1 group and FOS pathway

IL-10 anti-inflammatory signaling pathway

Serotonin receptor 2 and STAT3 signaling

Codeine and morphine metabolism

Androgen receptor network in prostate cancer

Osteoclast signaling

Oxysterols derived from cholesterol

Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism

17q12 copy number variation syndrome

Estradiol regulation in porto-sinusoidal vascular disease

Inclusion body myositis

Type I interferon induction and signaling during SARS-CoV-2 infection

Fatty acid biosynthesis

Fatty acid biosynthesis

Complement system

Genetic causes of porto-sinusoidal vascular disease

Markers of kidney cell lineage

Leukotriene metabolic pathway

Network map of SARS-CoV-2 signaling pathway

Kynurenine pathway and links to cell senescence

SARS-CoV-2 innate immunity evasion and cell-specific immune response

GDNF/RET signaling axis

GDNF/RET signaling axis

Fragile X syndrome

Prader-Willi and Angelman syndrome

Ovarian infertility

Primary carbon metabolism

Flowering time pathway

Purine metabolism

Phase I biotransformations, non P450

Translation factors

mRNA processing

Ethanol effects on histone modifications

Vitamin A and carotenoid metabolism

Sudden infant death syndrome (SIDS) susceptibility pathways

TCA cycle in senescence

Glycolysis in senescence

Pentose phosphate pathway in senescent cells

16p11.2 distal deletion syndrome

15q11.2 copy number variation syndrome

1q21.1 copy number variation syndrome

Gamma-glutamyl cycle for the biosynthesis and degradation of glutathione, including diseases

Methionine metabolism leading to sulfur amino acids and related disorders

Vitamin B6-dependent and responsive disorders

Pyrimidine metabolism and related diseases

Purine metabolism and related disorders

Biosynthesis and regeneration of tetrahydrobiopterin and catabolism of phenylalanine

Degradation pathway of sphingolipids, including diseases

Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling

MECP2 and associated Rett syndrome

Pregnane X receptor pathway

Cholestasis

Bardet-Biedl syndrome

Arsenic metabolism and reactive oxygen species generation

2q37 copy number variation syndrome

2q21.1 copy number variation syndrome

2q13 copy number variation syndrome

2q11.2 copy number variation syndrome

Alstrom syndrome

Dravet syndrome

Cholesterol synthesis disorders

Creatine pathway

Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins

mRNA processing

Myometrial relaxation and contraction pathways

mRNA processing

Myometrial relaxation and contraction pathways

COVID-19, thrombosis and anticoagulation

CAMKK2 pathway

Acute viral myocarditis

Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling

Overview of nanoparticle effects

Folate metabolism

MicroRNAs in cardiomyocyte hypertrophy

Vitamin B12 metabolism

Physiological and pathological hypertrophy of the heart

Linoleic acid metabolism affected by SARS-CoV-2

Mitochondrial immune response to SARS-CoV-2

Retinoblastoma gene in cancer

One-carbon metabolism

Hair follicle development: cytodifferentiation - part 3 of 3

Pre-implantation embryo

miRNA targets in ECM and membrane receptors

Pluripotent stem cell differentiation pathway

Allograft rejection

Hematopoietic stem cell gene regulation by GABP alpha/beta complex

MAPK pathway in congenital thyroid cancer

Downregulation of ACE2 by SARS-CoV-2 spike protein

Apoptosis modulation and signaling

IL-2 signaling pathway

Leukocyte-intrinsic Hippo pathway functions

DNA IR-damage and cellular response via ATR

4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression

Wnt signaling pathway

Corticotropin-releasing hormone signaling pathway

Angiopoietin-like protein 8 regulatory pathway

Melatonin metabolism and effects

SARS-CoV-2 and ACE2 receptor: molecular mechanisms

STING pathway in Kawasaki-like disease and COVID-19

GPR143 in melanocytes and retinal pigment epithelium cells

LDLRAD4 and what we know about it

SARS-CoV-2 and COVID-19 pathway

RAC1/PAK1/p38/MMP2 pathway

COVID-19 adverse outcome pathway

Photodynamic therapy-induced AP-1 survival signaling

Fluoropyrimidine activity

Cholesterol biosynthesis pathway

Familial hyperlipidemia type 3

Familial hyperlipidemia type 2

Familial hyperlipidemia type 1

Acquired partial lipodystrophy / Barraquer-Simons syndrome

Neuroinflammation and glutamatergic signaling

Kallmann syndrome

Riboflavin and CoQ disorders

Ethylmalonic encephalopathy

Overlap between signal transduction pathways contributing to LMNA laminopathies

Kisspeptin/kisspeptin receptor system in the ovary

Influence of laminopathies on Wnt signaling

Thyroid hormones production and peripheral downstream signaling effects

Serine metabolism

Joubert syndrome

Urea cycle and associated pathways

Urea cycle and related diseases

Hippo signaling regulation pathways

Tyrosine metabolism and related disorders

Lamin A-processing pathway

Thiamine metabolic pathways

MTHFR deficiency

Vitamin B12 disorders

Krebs cycle disorders

GABA metabolism (aka GHB)

Mecp2 and associated Rett syndrome

nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell

MFAP5-mediated ovarian cancer cell motility and invasiveness

22q11.2 copy number variation syndrome

Cerebral organic acidurias, including diseases

Male infertility

Parkinson's disease pathway

Parkin-ubiquitin proteasomal system pathway

Vitamin D receptor pathway

Alzheimer's disease and miRNA effects

Small cell lung cancer

Tryptophan metabolism

Major receptors targeted by epinephrine and norepinephrine

Alternative pathway of fetal androgen synthesis

Metabolic pathway of LDL, HDL and TG, including diseases

Glycosylation and related congenital defects

Cysteine and methionine catabolism

Modified nucleosides derived from tRNA as urinary cancer markers

Non-small cell lung cancer

Hereditary leiomyomatosis and renal cell carcinoma pathway

Prion disease pathway

Complement and coagulation cascades

Host-pathogen interaction of human coronaviruses - MAPK signaling

Rett syndrome causing genes

Disorders of folate metabolism and transport

Bladder cancer

Arrhythmogenic right ventricular cardiomyopathy

HIF1A and PPARG regulation of glycolysis

Progeria-associated lipodystrophy

Congenital generalized lipodystrophy

Nucleotide excision repair in xeroderma pigmentosum

Vitamin D-sensitive calcium signaling in depression

Glycogen synthesis and degradation

Proximal tubule transport

Host-pathogen interaction of human coronaviruses - interferon induction

Mammalian disorder of sexual development

Genes controlling nephrogenesis

Chromosomal and microsatellite instability in colorectal cancer

Endometrial cancer

Epithelial to mesenchymal transition in colorectal cancer

Distal convoluted tubule 1 (DCT1) cell

NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence

Endoplasmic reticulum stress response in coronavirus infection

ErbB signaling pathway

Ovarian infertility

SARS-CoV-2 altering angiogenesis via NRP1

Flowering time pathway

FOXP3 in COVID-19

7q11.23 copy number variation syndrome

Meta pathway lipodystrophy, dyslipidemia and hyperlipidemia

Development of ureteric collection system

Nephrogenesis

Polar auxin transport

Fatty acid beta-oxidation 3

Fatty acid beta-oxidation 2

Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway

Glycogen metabolism

Mevalonate arm of cholesterol biosynthesis pathway

ERK1-ERK2 MAPK cascade

Cannabinoid receptor signaling

Striated muscle contraction pathway

Lung fibrosis

Glioblastoma signaling pathways

FGF signaling pathway

Photosynthetic carbon reduction

Sphingolipid pathway

Pentose phosphate metabolism

Pentose phosphate pathway

Deregulation of Rab and Rab effector genes in bladder cancer

Nitric oxide metabolism in cystic fibrosis

Prostaglandin synthesis and regulation

Parkinson's disease

Electron transport chain

Acetylcholine synthesis

GPCRs, orphan

Endochondral ossification

Selenium metabolism / selenoproteins

Conversion of angiotensinogen to angiotensin II

Cholesterol biosynthesis with skeletal dysplasias

MED and pseudoachondroplasia genes

Neural crest cell migration in cancer

Ethanol metabolism production of ROS by CYP2E1

lncRNA in canonical Wnt signaling and colorectal cancer

MYD88 distinct input-output pathway

Amplification and expansion of oncogenic pathways as metastatic traits

lncRNA-mediated mechanisms of therapeutic resistance

Interactions between LOXL4 and oxidative stress pathway

Hypothesized pathways in pathogenesis of cardiovascular disease

Metabolism of dichloroethylene by CYP450

Biochemical pathways: part I

Circadian rhythm genes

MicroRNA for targeting cancer growth and vascularization in glioblastoma

Estrogen receptor pathway

Glucocorticoid receptor pathway

Constitutive androstane receptor pathway

Diclofenac metabolic pathway

Gastric cancer network 2

Gastric cancer network 1

Deregulation of Rab and Rab effector genes in bladder cancer

Osteoblast signaling

Monoterpene biosynthesis pathway in mint

Flowering time pathway

Fluoropyrimidine activity

TCA cycle nutrient use and invasiveness of ovarian cancer

Thyroid stimulating hormone (TSH) signaling pathway

Gastric cancer network 1

Polar auxin transport

Glyoxylate, anapleurotic and succinyl CoA (GAS) pathway

Tryptophan degradation

Phenylalanine, tyrosine, and tryptophan biosynthesis

P-cymene degradation

Toll, IMD, JAK/STAT pathways for immune response to pathogens

Polyol pathway

GPR40 pathway

TCA cycle nutrient use and invasiveness of ovarian cancer

Hematopoietic stem cell differentiation

Notch signaling

miRNA biogenesis

Synaptic vesicle pathway

Focal adhesion

Oxidative stress response

Exercise-induced circadian regulation

Calcium regulation in cardiac cells

EGFR tyrosine kinase inhibitor resistance

Acetylcholine synthesis

Ectoderm differentiation

PCSK9-mediated LDL receptor degradation

FOXA2 pathway

Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome

Regulation of apoptosis by parathyroid hormone-related protein

Host-pathogen interaction of human coronaviruses - apoptosis

Host-pathogen interaction of human coronaviruses - autophagy

Aspirin and miRNAs

One-carbon metabolism

Metabolism overview

Retinoblastoma gene in cancer

DNA damage response (only ATM dependent)

Disruption of postsynaptic signaling by CNV

Somatic sex determination

Netrin-UNC5B signaling pathway

Wnt signaling

BMP2-WNT4-FOXO1 pathway in primary endometrial stromal cell differentiation

Canonical and non-canonical TGF-B signaling

Phytochrome signaling pathway to turn on photomorphogenesis

Oxytocin signaling

Farnesoid X receptor pathway

PPAR-alpha pathway

Liver X receptor pathway

Endoderm differentiation

Alzheimer's disease

Sterol regulatory element-binding proteins (SREBP) signaling

TGF-beta signaling pathway

SARS coronavirus and innate immunity

15q13.3 copy number variation syndrome

3q29 copy number variation syndrome

Lung fibrosis

Amyotrophic lateral sclerosis (ALS)

Unfolded protein response

Pilocytic astrocytoma

Amino acid conjugation of benzoic acid

Genes related to primary cilium development (based on CRISPR)

Splicing factor NOVA regulated synaptic proteins

Nanomaterial induced apoptosis

Genetic alterations of lung cancer

Purinergic signaling

Peroxiredoxin 2 induced ovarian failure

Regucalcin in proximal tubule epithelial kidney cells

Peroxiredoxin 2 induced ovarian failure

MAP3K1 role in promoting and blocking gonadal determination

Envelope proteins and their potential roles in EDMD physiopathology

ErbB signaling pathway

ErbB signaling pathway

Tumor suppressor activity of SMARCB1

Corticotropin-releasing hormone

Lipids measured in liver metastasis from breast cancer

Cancer immunotherapy by PD-1 blockade

Cancer immunotherapy by CTLA4 blockade

MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement

FABP4 in ovarian cancer

Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors

ncRNAs involved in STAT3 signaling in hepatocellular carcinoma

ncRNAs involved in Wnt signaling in hepatocellular carcinoma

Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer

Breast cancer pathway

miRNA regulation of p53 pathway in prostate cancer

miRNA regulation of prostate cancer signaling pathways

mir-193a and MVP in colon cancer metastasis

PDGFR-beta pathway

miR-509-3p alteration of YAP1/ECM axis

RIOK1 and RIOK2 in EGFR- and PI3K-mediated tumorigenesis

Tamoxifen metabolism

Apoptosis-related network due to altered Notch3 in ovarian cancer

Apoptosis-related network due to altered Notch3 in ovarian cancer

PI3K-AKT-mTOR signaling pathway and therapeutic opportunities

Neovascularisation processes

Cell migration and invasion through p75NTR

Polyol pathway

Oxidative phosphorylation

Ethanol metabolism resulting in production of ROS by CYP2E1

Ethanol metabolism resulting in production of ROS by CYP2E1

Phosphodiesterases in neuronal function

Valproic acid pathway

Cytosine methylation

Oxytocin signaling

PPAR signaling pathway

Metapathway biotransformation Phase I and II

NRF2 pathway

Photodynamic therapy-induced NF-kB survival signaling

Photodynamic therapy-induced HIF-1 survival signaling

Photodynamic therapy-induced unfolded protein response

Thermogenesis

mRNA, protein, and metabolite inducation pathway by cyclosporin A

Septum site determination

Tryptophan metabolism

Polyol pathway

Oxidative phosphorylation

Polyol pathway

Polyol pathway

Polyol pathway

Tryptophan metabolism

Transcription factor regulation in adipogenesis

Biotin metabolism

miRNAs and TFs in iPS Cell Generation

Mismatch repair

Tryptophan metabolism

Tryptophan metabolism

Regulatory circuits of the STAT3 signaling pathway

Selective expression of chemokine receptors during T-cell polarization

Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms

Intraflagellar transport proteins binding to dynein

Signal transduction through IL1R

Ciliary landscape

Nanoparticle triggered autophagic cell death

Glyoxylate cycle

Intracellular trafficking of CFTR

Heterochronic gene regulation of development

Cell engulfment

Sleep regulation

p53 signaling

Peptide GPCRs