Endochondral ossification (WP1270)
Mus musculus
For a description of pathway objects, see the WikiPathways Legend.
Authors
Alex Pico , Egon Willighagen , Susan Coort , Friederike Ehrhart , and Eric WeitzActivity
Discuss this pathway
Check for ongoing discussions or start your own.
Cited In
- Hepatic transcriptome implications for palm fruit juice deterrence of type 2 diabetes mellitus in young male Nile rats (2016).
- Proteomic profiling of salivary gland after nonviral gene transfer mediated by conventional plasmids and minicircles (2014).
- Simultaneous time course analysis of multiple markers based on DNA microarray in incised wound in skeletal muscle for wound aging (2016).
- Transcriptome analysis in cardiomyocyte-specific differentiation of murine embryonic stem cells reveals transcriptional regulation network (2014).
- Mammary tissue microbiome analysis in PyMT mice reveals Methylobacteria as a commensal organism with potential therapeutic applications (2025).
Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.
Organisms
Mus musculusCommunities
Annotations
Pathway Ontology
regulatory pathwayLabel | Type | Compact URI | Comment |
---|---|---|---|
Oxygen | Metabolite | hmdb:HMDB0001377 | |
Triiodothyronine | Metabolite | chebi:24864 | |
Thyroid hormone | Metabolite | chebi:60311 | |
cAMP | Metabolite | hmdb:HMDB0000058 | |
Alpl | GeneProduct | ncbigene:11647 | |
Spp1 | GeneProduct | ncbigene:20750 | |
Fgfr3 | GeneProduct | ncbigene:14184 | |
Mmp13 | GeneProduct | ncbigene:17386 | |
Acan | GeneProduct | ncbigene:11595 | |
Bmpr1a | GeneProduct | ncbigene:12166 | |
Ihh | GeneProduct | ncbigene:16147 | |
Fgfr1 | GeneProduct | ncbigene:14182 | |
Igf2 | GeneProduct | ncbigene:16002 | |
Bmp6 | GeneProduct | ncbigene:12161 | |
Igf1 | GeneProduct | ncbigene:16000 | |
Slc38a2 | GeneProduct | ncbigene:67760 | |
Tgfb1 | GeneProduct | ncbigene:21803 | |
Cab39 | GeneProduct | ncbigene:12283 | |
Mef2c | GeneProduct | ncbigene:17260 | |
Col2a1 | GeneProduct | ncbigene:12824 | |
Adamts5 | GeneProduct | ncbigene:23794 | |
Runx3 | GeneProduct | ncbigene:12399 | |
Pth | GeneProduct | ncbigene:19226 | |
Fgf18 | GeneProduct | ncbigene:14172 | |
Calm1 | GeneProduct | ncbigene:12313 | |
Scin | GeneProduct | ncbigene:20259 | PMID: 17097081 |
Runx2 | GeneProduct | ncbigene:12393 | |
Fgf2 | GeneProduct | ncbigene:14173 | |
Sox6 | GeneProduct | ncbigene:20679 | |
Ptch1 | GeneProduct | ncbigene:19206 | |
Enpp1 | GeneProduct | ncbigene:18605 | |
Prkaca | GeneProduct | ncbigene:18747 | |
Kif3a | GeneProduct | ncbigene:16568 | |
Chst11 | GeneProduct | ncbigene:58250 | |
Ctsl | GeneProduct | ncbigene:13039 | Taken as homologue to mouse Cathepsin L (Ctsl) |
Tgfb2 | GeneProduct | ncbigene:21808 | |
Akt1 | GeneProduct | ncbigene:11651 | |
Gli3 | GeneProduct | ncbigene:14634 | |
Hmgcs1 | GeneProduct | ncbigene:208715 | |
Vegfa | GeneProduct | ncbigene:22339 | |
Mmp9 | GeneProduct | ncbigene:17395 | |
Serpinh1 | GeneProduct | ncbigene:12406 | |
Bmp7 | GeneProduct | ncbigene:12162 | |
Cdkn1c | GeneProduct | ncbigene:12577 | |
Sox9 | GeneProduct | ncbigene:20682 | |
Thra | GeneProduct | ncbigene:21833 | |
Stat1 | GeneProduct | ncbigene:20846 | |
Adamts1 | GeneProduct | ncbigene:11504 | |
Ghr | GeneProduct | ncbigene:14600 | |
Plau | GeneProduct | ncbigene:18792 | |
Mgp | GeneProduct | ncbigene:17313 | |
Stat5b | GeneProduct | ncbigene:20851 | |
Col10a1 | GeneProduct | ncbigene:12813 | |
Adamts4 | GeneProduct | ncbigene:240913 | |
Igf1r | GeneProduct | ncbigene:16001 | |
Ift88 | GeneProduct | ncbigene:21821 | |
Ddr2 | GeneProduct | ncbigene:18214 | |
Nkx3-2 | GeneProduct | ncbigene:12020 | |
Cst10 | GeneProduct | ncbigene:58214 | Taken as human homologue of mouse Cst10PMID: 13679380 |
Frzb | GeneProduct | ncbigene:20378 | |
Plat | GeneProduct | ncbigene:18791 | |
Hdac4 | GeneProduct | ncbigene:208727 | |
Pthlh | GeneProduct | ncbigene:19227 | |
Pth1r | GeneProduct | ncbigene:19228 | |
Sox5 | GeneProduct | ncbigene:20678 | |
Timp3 | GeneProduct | ncbigene:21859 |
References
- Endochondral ossification: how cartilage is converted into bone in the developing skeleton. Mackie EJ, Ahmed YA, Tatarczuch L, Chen KS, Mirams M. Int J Biochem Cell Biol. 2008;40(1):46–62. PubMed Europe PMC Scholia
- A microarray approach for comparative expression profiling of the discrete maturation zones of mouse growth plate cartilage. Belluoccio D, Bernardo BC, Rowley L, Bateman JF. Biochim Biophys Acta. 2008 May;1779(5):330–40. PubMed Europe PMC Scholia