miRNAs and TFs in iPS Cell Generation (WP2375)

Mus musculus

This pathway describes how a set of miRNA is responsible for different steps of induced pluripotent stem cell generation in a mouse embryonic fibroblasts cell model, infected with Oct3/4, Sox2, Klf4 and c-Myc.


Susan Coort , Elisa Cirillo , Martina Summer-Kutmon , and Friederike Ehrhart


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Mus musculus



Pathway Ontology

regulatory pathway


Label Type Compact URI Comment
Phf5a GeneProduct ncbigene:68479
Prpf4 GeneProduct ncbigene:70052
Snrpa GeneProduct ncbigene:53607
Bat1a GeneProduct ncbigene:53817
Oct4 GeneProduct ncbigene:18999
Sox2 GeneProduct ncbigene:20674
Sf3a3 GeneProduct ncbigene:75062


  1. Synergetic cooperation of microRNAs with transcription factors in iPS cell generation. Chen J, Wang G, Lu C, Guo X, Hong W, Kang J, et al. PLoS One. 2012;7(7):e40849. PubMed Europe PMC Scholia