SARS-CoV-2 innate immunity evasion and cell-specific immune response (WP5039)

Homo sapiens

Authors

Mario Alin Rus , Egon Willighagen , Nuray Talih , Martina Summer-Kutmon , Friederike Ehrhart , Eric Weitz , Nhung Pham , and Lars Willighagen

Activity

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Cited In

• The Biological Interaction of SARS-CoV-2 Infection and Osteoporosis: A Preliminary Study (2022).
• Identification of Robust Protein Associations With COVID-19 Disease Based on Five Clinical Studies (2022).
• Clinical improvement of DM1 patients reflected by reversal of disease-induced gene expression in blood (2022).

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Organisms

Homo sapiens

Communities

COVID-19

Annotations

Disease Ontology

severe acute respiratory syndrome COVID-19

Pathway Ontology

disease pathway immune response pathway

References

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2. Impaired type I interferon activity and exacerbated inflammatory responses in severe Covid-19 patients [Internet]. Hadjadj J, Yatim N, Barnabei L, Corneau A, Boussier J, Péré H, et al. Cold Spring Harbor Laboratory; 2020. Available from: http://dx.doi.org/10.1101/2020.04.19.20068015 DOI Scholia
3. SARS-CoV-2 ORF6 disrupts nucleocytoplasmic transport through interactions with Rae1 and Nup98 [Internet]. Addetia A, Lieberman NAP, Phung Q, Xie H, Roychoudhury P, Shrestha L, et al. Cold Spring Harbor Laboratory; 2020. Available from: http://dx.doi.org/10.1101/2020.08.03.234559 DOI Scholia
4. Viral Invasion and Type I Interferon Response Characterize the Immunophenotypes during COVID-19 Infection. Wei L, Ming S, Zou B, Wu Y, Hong Z, Li Z, et al. SSRN Journal [Internet]. 2020; Available from: http://dx.doi.org/10.2139/ssrn.3555695 DOI Scholia
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10. A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Gordon DE, Jang GM, Bouhaddou M, Xu J, Obernier K, White KM, et al. Nature. 2020 Jul;583(7816):459–68. PubMed Europe PMC Scholia
11. Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19. Blanco-Melo D, Nilsson-Payant BE, Liu WC, Uhl S, Hoagland D, Møller R, et al. Cell. 2020 May 28;181(5):1036-1045.e9. PubMed Europe PMC Scholia
12. SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists. Yuen CK, Lam JY, Wong WM, Mak LF, Wang X, Chu H, et al. Emerg Microbes Infect. 2020 Dec;9(1):1418–28. PubMed Europe PMC Scholia
13. The ORF3a protein of SARS-CoV-2 induces apoptosis in cells. Ren Y, Shu T, Wu D, Mu J, Wang C, Huang M, et al. Cell Mol Immunol. 2020 Aug;17(8):881–3. PubMed Europe PMC Scholia
14. Covid-19: Perspectives on Innate Immune Evasion. Taefehshokr N, Taefehshokr S, Hemmat N, Heit B. Front Immunol. 2020 Sep 30;11:580641. PubMed Europe PMC Scholia
15. COVID-19: The Emerging Immunopathological Determinants for Recovery or Death. Ahmad T, Chaudhuri R, Joshi MC, Almatroudi A, Rahmani AH, Ali SM. Front Microbiol. 2020 Dec 1;11:588409. PubMed Europe PMC Scholia
16. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling. Zheng Y, Zhuang MW, Han L, Zhang J, Nan ML, Zhan P, et al. Signal Transduct Target Ther. 2020 Dec 28;5(1):299. PubMed Europe PMC Scholia
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