Paullinia cupana caffeine synthesis (WP5590)

Paullinia cupana

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Paullinia cupana caffeine synthesis pathway.

For a description of pathway objects, see the WikiPathways Legend.

Authors

Hayashi and Egon Willighagen

Activity

last edited

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Cited In

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Organisms

Paullinia cupana

Communities

Plants

Annotations

Pathway Ontology

classic metabolic pathway

Participants

Label Type Compact URI Comment
Xanthine Metabolite chebi:15318
3-methylxanthine Metabolite chebi:62208
caffeine Metabolite chebi:27732
Theobromine Metabolite chebi:28946
PcCS GeneProduct wikidata:Q136645637
PcCS1 GeneProduct wikidata:Q136645635
PcCS2 GeneProduct wikidata:Q136645636

References

  1. Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes. Huang R, O’Donnell AJ, Barboline JJ, Barkman TJ. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10613–8. PubMed Europe PMC Scholia
  2. Convergent Biochemical Pathways for Xanthine Alkaloid Production in Plants Evolved from Ancestral Enzymes with Different Catalytic Properties. O’Donnell AJ, Huang R, Barboline JJ, Barkman TJ. Mol Biol Evol. 2021 Jun 25;38(7):2704–14. PubMed Europe PMC Scholia