Abnormal calcium handling and its effects on muscle contraction in DMD (WP5343)

Homo sapiens

Abnormal calcium handling and its effects on muscle contraction in DMD


Tom Bausch , Javier Millán Acosta , and Egon Willighagen


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Homo sapiens


Diseases Rare Diseases


Pathway Ontology

altered calcium/calcium-mediated signaling pathway disease pathway muscular disease pathway

Disease Ontology

Duchenne muscular dystrophy atrophic muscular disease muscular disease


Label Type Compact URI Comment
leukotrienes Metabolite chebi:25029
lysophospholipids Metabolite chebi:16961
Platelet activating factor Metabolite chebi:44811
IP3R Metabolite chebi:131186
Ca2+ Metabolite chebi:29108
prostaglandins Metabolite chebi:26333
Ca2+ Metabolite chebi:29108
Ca2+ Metabolite chebi:29108
Ca2+ Metabolite chebi:29108
Ca2+ Metabolite chebi:29108
Ca2+ Metabolite chebi:29108
Phospholipase A2 GeneProduct hgnc.symbol:PLA2G4B
CASQ 1 GeneProduct hgnc.symbol:CASQ1
Dystrobrevin alpha GeneProduct hgnc.symbol:DTNA
Calpain 3 GeneProduct hgnc.symbol:CAPN3
SERCA 1 GeneProduct hgnc.symbol:ATP2A1
Syntrophin beta-1 GeneProduct hgnc.symbol:SNTB1
Troponin C GeneProduct hgnc.symbol:TNNC2
alpha sarcoglycan GeneProduct hgnc.symbol:SGCA
RyR 1 GeneProduct hgnc.symbol:RYR1
Triadin GeneProduct hgnc.symbol:TRDN
Voltage gated Ca2+ channel GeneProduct hgnc.symbol:CACNG1
Sarcospan GeneProduct hgnc.symbol:SSPN
Dystrophin GeneProduct hgnc.symbol:DMD
Dystroglycan 1 GeneProduct hgnc.symbol:DAG1


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