Female steroid hormones in cardiomyocyte energy metabolism (WP5318)

Homo sapiens

Estrogen and Progesterone affect energy metabolism in cardiomyocytes.


Mehaa Prabakar , Natalie Varahram , Liana Tyrrell , Egon Willighagen , Andra Waagmeester , and Alex Pico


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Homo sapiens



Pathway Ontology

classic metabolic pathway


Label Type Compact URI Comment
Tamoxifen Metabolite chebi:41774
cAMP Metabolite chebi:17489
Estrogen Metabolite chebi:50114
Estrogen Metabolite chebi:50114
Estrogen Metabolite chebi:50114
Estrogen Metabolite chebi:50114
MTP GeneProduct ensembl:ENSG00000138823
cTNL GeneProduct kegg.genes:hsa:1514
FoxO1 GeneProduct uniprot:UP000005640
GLUT4 GeneProduct ensembl:ENSG00000181856
ppara GeneProduct ensembl:ENSG00000186951
HADHB GeneProduct ensembl:ENSG00000138029
GATA4 GeneProduct ensembl:ENSG00000181856
MYH6 GeneProduct uniprot:UP000005640
Inhibition of TNF-a GeneProduct uniprot:UP000005640
HADHB GeneProduct ensembl:ENSG00000138029
GLUT4 GeneProduct ensembl:ENSG00000181856
ROS GeneProduct uniprot:UP000002494
acadm GeneProduct ensembl:ENSG00000117054
Elk-1 GeneProduct uniprot:UP000005640
MEF2 GeneProduct uniprot:UP0000005640
GLUT1 GeneProduct ensembl:ENSG00000181856
PKB Protein ensembl:ENSG00000105221
Apob-lipoprotein Protein ensembl:ENSG00000084674
LKB1 Protein ensembl:ENSG00000118046
ERa Protein uniprot:P03372
Troponin Protein uniprot:UP000005640
PGC-1α Protein uniprot:Q86YN6
RyR2 Protein ensembl:ENST000006099119.1
eNOS Protein ensembl:ENSG00000164867
PPARα Protein uniprot:Q07869
MCAD Protein uniprot:P11310
ATP citrate synthase Protein uniprot:P53396
NOS3 Protein ensembl:ENSG00000164867
ERRa Protein uniprot:P11474
ERRa Protein uniprot:P11474
ERb Protein uniprot:P11474
Progesterone Protein uniprot:P11474
PGR Protein uniprot:P11474
ERa Protein uniprot:P03372
ERa Protein uniprot:P03372
ERa Protein uniprot:P03372


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