COVID-19 and endothelial cell senescence (WP5256)

Homo sapiens

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GABA SARS-CoV-2

Authors

Laure-Alix Clerbaux , Egon Willighagen , Eric Weitz , Denise Slenter , and John Figueira Hasbun

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

COVID-19

Annotations

Pathway Ontology

type I interferon signaling pathway signaling pathway

Disease Ontology

viral infectious disease COVID-19 severe acute respiratory syndrome

Participants
Query Drugst.One

Label Type Compact URI Comment
IL17RA GeneProduct ensembl:ENSG00000177663
ANO6 GeneProduct ensembl:ENSG00000177119
IL17A GeneProduct ensembl:ENSG00000112115
IL17RC GeneProduct ensembl:ENSG00000163702
TLR4 Protein uniprot:O00206
orf3a Protein uniprot:P0DTC3 PDB structure for SARS-CoV strain: 6JYT
orf8 Protein uniprot:P0DTC8 PDB structure for SARS-CoV strain: 6JYT
nsp4 Protein uniprot:PRO_0000449622 PDB structure for SARS-CoV strain: 6JYT; PRO_0000449622

References

  1. Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8. Wu X, Xia T, Shin WJ, Yu KM, Jung W, Herrmann A, et al. mBio. 2022 Apr 26;13(2):e0040222. PubMed Europe PMC Scholia