Arachidonic acid (AA, ARA) oxylipin metabolism (WP5155)
Homo sapiens
Arachidonic acid (AA or ARA) oxlipin metabolism
Authors
Lucien Cayer and Eric WeitzActivity
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Organisms
Homo sapiensCommunities
Annotations
Pathway Ontology
eicosanoid metabolic pathway| Label | Type | Compact URI | Comment |
|---|---|---|---|
| EXA4 | Metabolite | chebi:63983 | |
| Trioxilin A3 | Metabolite | pubchem.compound:5283208 | |
| 15-keto-PGF2alpha | Metabolite | pubchem.compound:5280887 | |
| TXA2 | Metabolite | chebi:15627 | |
| HXA3 | Metabolite | chebi:36190 | |
| 5,15-DiHETE | Metabolite | chebi:91286 | |
| 5,6-DiHETrE | Metabolite | chebi:63974 | |
| 11beta-PGF2alpha | Metabolite | pubchem.compound:5280886 | |
| Tetranor 12-HETE | Metabolite | hmdb:HMDB60055 | |
| PGA2 | Metabolite | chebi:133370 | |
| 5,12-DiHETE | Metabolite | chebi:15647 | |
| 13,14-dihydro-15-keto-PGE2 | Metabolite | pubchem.compound:5280711 | |
| 5(6)-EpETrE | Metabolite | pubchem.compound:5283202 | |
| 6-keto-PGF1alpha | Metabolite | pubchem.compound:5280888 | |
| PGD2 | Metabolite | chebi:15555 | |
| delta(12)-PGJ2 | Metabolite | pubchem.compound:5280885 | |
| 2,3-dinor-TXB2 | Metabolite | pubchem.compound:5283138 | |
| 11-dehydro-TXB2 | Metabolite | pubchem.compound:5280891 | |
| 8(9)-EpETrE | Metabolite | pubchem.compound:5283203 | |
| 15-deoxy-delta(12,14)-PGJ2 | Metabolite | pubchem.compound:5311211 | |
| 11-oxo-ETE | Metabolite | wikidata:Q27162742 | |
| 16-HETE | Metabolite | wikidata:Q27070786 | |
| PGE2 | Metabolite | chebi:15551 | |
| 14,15-DiHETrE | Metabolite | chebi:63966 | |
| ASA | Metabolite | chebi:15365 | |
| 9-HETE | Metabolite | chebi:72785 | |
| LTE4 | Metabolite | chebi:15650 | |
| 15-epi-LXA4 | Metabolite | pubchem.compound:9841438 | |
| 20-carboxy-LTB4 | Metabolite | pubchem.compound:5280877 | |
| 15-keto-PGE2 | Metabolite | pubchem.compound:5280719 | |
| 19-HETE | Metabolite | wikidata:Q27132956 | |
| 12-HHTrE | Metabolite | pubchem.compound:5312765 | |
| 12-oxo-ETE | Metabolite | chebi:34151 | |
| 11(12)-EpETrE | Metabolite | pubchem.compound:5283204 | |
| 8-HpETE | Metabolite | pubchem.compound:6438881 | |
| LTB4 | Metabolite | chebi:15647 | |
| LTA4 | Metabolite | pubchem.compound:5280383 | |
| PGJ2 | Metabolite | pubchem.compound:5280884 | |
| 15-epi-LXB4 | Metabolite | chebi:63991 | |
| 8-oxo-ETE | Metabolite | wikidata:Q27145567 | |
| 15-keto-PGD2 | Metabolite | pubchem.compound:5280727 | |
| TXB2 | Metabolite | chebi:28728 | |
| EXE4 | Metabolite | chebi:63986 | |
| 12-HpETE | Metabolite | chebi:15626 | |
| 15(R)-HpETE | Metabolite | pubchem.compound:10042663 | |
| 8-HETE | Metabolite | hmdb:HMDB04679 | |
| 15-HETE | Metabolite | chebi:64017 | |
| 8,15-DiHETE | Metabolite | hmdb:HMDB10219 | |
| 5-HpETE | Metabolite | pubchem.compound:5283171 | |
| 15-oxo-ETE | Metabolite | chebi:15559 | |
| 13,14-dihydro-15-keto-PGD2 | Metabolite | pubchem.compound:5283036 | |
| LXB4 | Metabolite | chebi:6499 | |
| Trioxilin B3 | Metabolite | chebi:35032 | |
| 13,14-dihydro-15-keto-PGF2alpha | Metabolite | pubchem.compound:5283039 | |
| PGB2 | Metabolite | pubchem.compound:5280881 | |
| LXA4 | Metabolite | wikidata:Q27082450 | |
| EXC4 | Metabolite | chebi:63984 | |
| LTF4 | Metabolite | chebi:27491 | |
| 11-HETE | Metabolite | wikidata:Q27140010 | |
| 8,9-DiHETrE | Metabolite | chebi:63970 | |
| 20-HETE | Metabolite | chebi:34306 | |
| 12-HETE | Metabolite | hmdb:HMDB06111 | |
| PGI2 | Metabolite | chebi:15552 | |
| 12,20-DiHETE | Metabolite | hmdb:HMDB60105 | |
| 9-HpETE | Metabolite | chebi:78732 | |
| 11-HpETE | Metabolite | pubchem.compound:5283174 | |
| HXB3 | Metabolite | chebi:34784 | |
| 15-HpETE | Metabolite | hmdb:HMDB62688 | |
| ARA | Metabolite | hmdb:HMDB01043 | |
| 5,20-DiHETE | Metabolite | hmdb:HMDB62614 | |
| 5-oxo-ETE | Metabolite | pubchem.compound:5283159 | |
| LTD4 | Metabolite | chebi:28666 | |
| PGH2 | Metabolite | chebi:15554 | |
| PGF2alpha | Metabolite | chebi:15553 | |
| EXD4 | Metabolite | chebi:63985 | |
| 14(15)-EpETrE | Metabolite | pubchem.compound:5283205 | |
| LTC4 | Metabolite | chebi:16978 | |
| 5-HETE | Metabolite | hmdb:HMDB11134 | |
| 17-HETE | Metabolite | hmdb:HMDB12598 | |
| 18-HETE | Metabolite | chebi:63579 | |
| 11,12-DiHETrE | Metabolite | chebi:63969 | |
| 20-hydroxy-LTB4 | Metabolite | pubchem.compound:5280745 | |
| tetranor-PGEM | Metabolite | pubchem.compound:161468 | |
| COX1 | GeneProduct | ncbigene:5742 | |
| COX2 | GeneProduct | ncbigene:5743 | |
| COX2 | GeneProduct | ncbigene:5743 | |
| EPHX2 | GeneProduct | ensembl:ENSG00000120915 | |
| TBXAS1 | GeneProduct | ncbigene:6916 |
References
- Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis. Smith WL, Urade Y, Jakobsson PJ. Chem Rev. 2011 Oct 12;111(10):5821–65. PubMed Europe PMC Scholia