Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex (WP4884)

Homo sapiens

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Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis

For a description of pathway objects, see the WikiPathways Legend.

Authors

Rex D A B , Kristina Hanspers , Egon Willighagen , Alex Pico , Eric Weitz , Finterly Hu , and Isabel Wassink

Activity

last edited

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Cited In

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Organisms

Homo sapiens

Communities

COVID-19

Annotations

Pathway Ontology

disease pathway inflammatory response pathway regulatory pathway

Disease Ontology

severe acute respiratory syndrome viral infectious disease COVID-19

Participants
Query Drugst.One

Label Type Compact URI Comment
IGLC2 GeneProduct ncbigene:3538
IGHE GeneProduct ncbigene:3497
HLA-DRA GeneProduct ncbigene:3122
CD4 GeneProduct ncbigene:920
CD8B GeneProduct ncbigene:926
HLA-DRB1 GeneProduct ncbigene:3123
IGLL1 GeneProduct ncbigene:3543
PRG3 GeneProduct ncbigene:10394
CD8A GeneProduct ncbigene:925
CRP GeneProduct ncbigene:1401
MMP25 GeneProduct ncbigene:64386
LBP GeneProduct ncbigene:3929
HLA-DRB4 GeneProduct ncbigene:3126
IGHG4 GeneProduct ncbigene:3503
IL8 GeneProduct ncbigene:3576
IGHG2 GeneProduct ncbigene:3501
NKRF GeneProduct ncbigene:55922
CD2 GeneProduct ncbigene:914
NLRP1 GeneProduct ncbigene:5725029
HLA-DRB5 GeneProduct ncbigene:3127
IGHG1 GeneProduct ncbigene:3500
IL6 GeneProduct ncbigene:3569
CD247 GeneProduct ncbigene:919
CD3G GeneProduct ncbigene:917
LCK GeneProduct ncbigene:3932
CD3E GeneProduct ncbigene:916
ZAP70 GeneProduct ncbigene:7535
TRBC1 GeneProduct ncbigene:28639
FYN GeneProduct ncbigene:2534
TRAC GeneProduct ncbigene:28755
nsp9 Protein wikidata:Q89686805
nsp10 Protein wikidata:Q87917572

References

  1. Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis. Li J, Guo M, Tian X, Wang X, Yang X, Wu P, et al. Med (N Y). 2021 Jan 15;2(1):99-112.e7. PubMed Europe PMC Scholia