TCA cycle (WP19)

Danio rerio

Tricarboxylic acid (TCA) cycle in zebrafish. Also known as the Krebs cycle, this pathway releases energy stored in nutrients through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins.


Kdahlquist , Nick Fidelman , Egon Willighagen , Daniela Digles , Levi Wackers , Susan Coort , and Eric Weitz


last edited

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Danio rerio



Pathway Ontology

citric acid cycle pathway


Label Type Compact URI Comment
Succinate Metabolite chebi:30031
Succinyl-CoA Metabolite chebi:15380
Acetyl-CoA Metabolite chebi:15351
Pyruvate Metabolite chebi:15361
L-malate Metabolite chebi:15589
Fumarate Metabolite chebi:18012
Oxaloacetate Metabolite chebi:30744
L-malate Metabolite chebi:15589
Oxaloacetate Metabolite chebi:30744
Isocitrate Metabolite chebi:16087
Alpha-ketoglutarate Metabolite chebi:16810
Citrate Metabolite chebi:133748
pdha1a GeneProduct ncbigene:406702
ogdha GeneProduct ensembl:ENSDARG00000034270
suclg2 GeneProduct ensembl:ENSDARG00000044914
idh3b GeneProduct ensembl:ENSDARG00000044753
pdk1 GeneProduct ensembl:ENSDARG00000013128
pdk4 GeneProduct ensembl:ENSDARG00000054848
idh3a GeneProduct ensembl:ENSDARG00000030278
pdk2b GeneProduct ensembl:ENSDARG00000059054
sdhc GeneProduct ensembl:ENSDARG00000038608
pcxb GeneProduct ensembl:ENSDARG00000051939
idh2 GeneProduct ensembl:ENSDARG00000003795
mdh1aa GeneProduct ensembl:ENSDARG00000017772
aco2 GeneProduct ncbigene:322670
dldh GeneProduct ensembl:ENSDARG00000008785
dlat GeneProduct ncbigene:324201
fh GeneProduct ensembl:ENSDARG00000075132
sdha GeneProduct ensembl:ENSDARG00000016721
zgc:165532 GeneProduct ncbigene:ENSDARG00000016964
dlst GeneProduct ensembl:ENSDARG00000014230
pdp2 GeneProduct ensembl:ENSDARG00000058571
pdhb GeneProduct ncbigene:406428
cs GeneProduct ncbigene:ENSDARG00000103364
dldh GeneProduct ncbigene:399479
pdhx GeneProduct ensembl:ENSDARG00000051756
sucla2 GeneProduct ncbigene:ENSDARG00000005359
sdhb GeneProduct ensembl:ENSDARG00000075768
suclg1 GeneProduct ensembl:ENSDARG00000052712
pdk3b GeneProduct ensembl:ENSDARG00000099791
mdh2 GeneProduct ensembl:ENSDARG00000043371
sdhda GeneProduct ensembl:ENSDARG00000055712
sdhdb GeneProduct ensembl:ENSDARG00000030139
mdh1ab GeneProduct ensembl:ENSDARG00000103849
mdh1b GeneProduct ensembl:ENSDARG00000018008
pdha1b GeneProduct ensembl:ENSDARG00000010555
idh3b GeneProduct ensembl:ENSDARG00000044753