MicroRNA for targeting cancer growth and vascularization in glioblastoma (WP3593)

Homo sapiens

miR-148a and miR-31 target the factor inhibiting hypoxia (FIH1) to promote downstream HIF1α and Notch signaling
last edited


Kristina Hanspers , Ryan Miller , Alex Pico , Friederike Ehrhart , and Eric Weitz

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.


Homo sapiens




Pathway Ontology: glioma pathway microRNA pathway

Disease Ontology: glioblastoma


Label Type Compact Identifier Comment
HES1 GeneProduct ensembl:ENSG00000114315
MIR31 GeneProduct mirbase:MI0000089
VEGFA GeneProduct ensembl:ENSG00000112715
HIF1AN GeneProduct ensembl:ENSG00000166135
HEY1 GeneProduct ensembl:ENSG00000164683
HIF1A GeneProduct ensembl:ENSG00000100644
VEGFB GeneProduct ensembl:ENSG00000173511
VEGFC GeneProduct ensembl:ENSG00000150630
HIF1A GeneProduct ensembl:ENSG00000100644


  1. The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma. Wong HKA, Fatimy RE, Onodera C, Wei Z, Yi M, Mohan A, et al. Mol Ther. 2015 Jul;23(7):1234–47. PubMed Europe PMC Scholia