ArcPathVisio Brace Octagon Ellipse EndoplasmicReticulum HexagonPathVisio GolgiApparatus MimDegradation Mitochondria Octagon PentagonPathVisio Rectangle RoundedRectangle SarcoplasmicReticulum TrianglePathVisio none PDGF-BB complex Osteoclast activation Osteoclast Bone Ca2+ OPG H+ Pi H+ TRPV RANK ligand Ca2+ H+ H+ AIMP2 TRAP Cathepsin K IFN-b H+ Na+/H+ transporter Na+ H+ ATPase MAPK8 Na+ RANK TRAP Type 1 interferon receptor b3 integrin Cathepsin K OGR1 Osteopontin PDGFB PDGFB Name: Osteoclast signaling Last Modified: 20230611172915 Organism: Homo sapiens