wikipathways-collection

WikiPathways WP4549

• WikiPathways: WP4549 (classic)
• Species: Homo sapiens
• Scholia: WP4549

  Tests

• CASMetabolitesTests: all 2 tests OK!
• ChEBIMetabolitesTests: all 5 tests OK!
• ChemSpiderTests: all 2 tests OK!
• DataNodesTests
  • dataNodesWithoutIdentifier: .x we found 1 problem(s):
    • The following DataNodes have no identifier: 1
  • unknownTypes_knownDatasource: .. all OK!
  • unknownTypes: .. all OK!
  • unknownTypes_Reactome: .. all OK!
  • otherDataSource: .. all OK!
• EnsemblTests: all 4 tests OK!
• GeneTests: all 4 tests OK!
• GeneralTests: all 13 tests OK!
• HMDBSecMetabolitesTests: all 3 tests OK!
• InteractionTests
  • noMetaboliteToNonMetaboliteConversions: .. all OK!
  • noNonMetaboliteToMetaboliteConversions: .. all OK!
  • noGeneProteinConversions: .. all OK!
  • nonNumericIDs: .. all OK!
  • interactionsWithLabels: .x we found 1 problem(s):
    • Interactions found that involve Labels: 21
  • possibleTranslocations: .x we found 1 problem(s):
    • Interactions between identical nodes: 14
  • noProteinProteinConversions: .. all OK!
  • incorrectKEGGIdentifiers: .. all OK!
• KEGGMetaboliteTests: all 2 tests OK!
• LIPIDMAPSTests: all 1 tests OK!
• MetaboliteStructureTests: all 1 tests OK!
• MetabolitesTests: all 14 tests OK!
• OudatedDataSourcesTests: all 8 tests OK!
• PathwayTests: all 7 tests OK!
• ProteinsTests: all 2 tests OK!
• PubChemMetabolitesTests: all 3 tests OK!
• ReferencesTests: all 6 tests OK!
• UniProtTests: all 5 tests OK!
• WikidataTests: all 4 tests OK!

Summary

• Number of test classes: 20
• Number of tests: 99
• Number of assertions: 200
• Number of fails: 3

Fails

Data nodes without an identifier

The following DataNodes have no identifier: 1

http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/DataNode/b8d60 (CAMKIV-CREB Pathway)

More details at https://www.wikipathways.org/WikiPathwaysCurator/DataNodesTests/dataNodesWithoutIdentifier

InteractionTests.interactionsWithLabels

Interactions found that involve Labels: 21

http://classic.wikipathways.org/instance/WP4549_r127643 "Hippocampus CA1" with graphId bb8b9
http://classic.wikipathways.org/instance/WP4549_r127643 "mGluR-LTD

" with graphId b23f7
http://classic.wikipathways.org/instance/WP4549_r127643 "Subiculum " with graphId ceb77
http://classic.wikipathways.org/instance/WP4549_r127643 "Dysregulation of GABAergic 
synaptic transmission
" with graphId b7d58
http://classic.wikipathways.org/instance/WP4549_r127643 "Audiogenic seizures" with graphId aab06
http://classic.wikipathways.org/instance/WP4549_r127643 "C-fiber innervation" with graphId f31d0
http://classic.wikipathways.org/instance/WP4549_r127643 "release of Ca2+" with graphId ae4e6
http://classic.wikipathways.org/instance/WP4549_r127643 "Cerebellar cortex" with graphId ab818
http://classic.wikipathways.org/instance/WP4549_r127643 "Anterior cingulate 
cortex" with graphId a510b
http://classic.wikipathways.org/instance/WP4549_r127643 "Enteric innervation 
of the ileum" with graphId b1576
http://classic.wikipathways.org/instance/WP4549_r127643 "Hippocampus 
CA1" with graphId e7bbc
http://classic.wikipathways.org/instance/WP4549_r127643 "stalled
 polyribosomes" with graphId b3674
http://classic.wikipathways.org/instance/WP4549_r127643 "Basolateral 
Amygdala" with graphId fc0e9
http://classic.wikipathways.org/instance/WP4549_r127643 "Neocortical layer
5 neurons" with graphId b5fdb
http://classic.wikipathways.org/instance/WP4549_r127643 "Amygdala" with graphId b5f0c
http://classic.wikipathways.org/instance/WP4549_r127643 "mGluR-LTP
" with graphId d0e6c
http://classic.wikipathways.org/instance/WP4549_r127643 "Corticostriatal 
synapse" with graphId df32e
http://classic.wikipathways.org/instance/WP4549_r127643 "Somatosensory
Cortex" with graphId f07bf
http://classic.wikipathways.org/instance/WP4549_r127643 "Striatum" with graphId e2d51
http://classic.wikipathways.org/instance/WP4549_r127643 "Suprachiasmatic 
nucleus" with graphId c9c06
http://classic.wikipathways.org/instance/WP4549_r127643 "Defective 
cAMP 
production" with graphId bdfcb

Possible MIM translocation

Interactions between identical nodes: 14

http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id186dec8f "FMR1" (https://identifiers.org/ensembl/ENSG00000102081) and 
FMR1" (https://identifiers.org/ensembl/ENSG00000102081)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id9aa2e278 "GRIN2B" (https://identifiers.org/ensembl/ENSG00000273079) and 
GRIN2B" (https://identifiers.org/ensembl/ENSG00000273079)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id9daeda7b "CREB1" (https://identifiers.org/ensembl/ENSG00000118260) and 
CREB1" (https://identifiers.org/ensembl/ENSG00000118260)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id41bbefae "RHEB" (https://identifiers.org/ensembl/ENSG00000106615) and 
RHEB" (https://identifiers.org/ensembl/ENSG00000106615)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id3c0843cf "FMR1" (https://identifiers.org/ensembl/ENSG00000102081) and 
FMR1" (https://identifiers.org/ensembl/ENSG00000102081)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id8522480f "MKNK1" (https://identifiers.org/ensembl/ENSG00000079277) and 
MKNK1" (https://identifiers.org/ensembl/ENSG00000079277)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id7ceedc8c "EIF4EBP2" (https://identifiers.org/ensembl/ENSG00000148730) and 
EIF4EBP2" (https://identifiers.org/ensembl/ENSG00000148730)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/idcfdaba90 "GRIN2B" (https://identifiers.org/ensembl/ENSG00000273079) and 
GRIN2B" (https://identifiers.org/ensembl/ENSG00000273079)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id65826470 "KRAS" (https://identifiers.org/ensembl/ENSG00000133703) and 
KRAS" (https://identifiers.org/ensembl/ENSG00000133703)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id7a1b768e "KRAS" (https://identifiers.org/ensembl/ENSG00000133703) and 
KRAS" (https://identifiers.org/ensembl/ENSG00000133703)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id71a70594 "GRIN2B" (https://identifiers.org/ensembl/ENSG00000273079) and 
GRIN2B" (https://identifiers.org/ensembl/ENSG00000273079)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id1531d62a "GRIN2B" (https://identifiers.org/ensembl/ENSG00000273079) and 
GRIN2B" (https://identifiers.org/ensembl/ENSG00000273079)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id5e4da64f "MAPK1" (https://identifiers.org/ensembl/ENSG00000100030) and 
MAPK1" (https://identifiers.org/ensembl/ENSG00000100030)
http://classic.wikipathways.org/instance/WP4549_r127643 http://rdf.wikipathways.org/Pathway/WP4549_r127643/WP/Interaction/id3315d84f "RHEB" (https://identifiers.org/ensembl/ENSG00000106615) and 
RHEB" (https://identifiers.org/ensembl/ENSG00000106615)

More details at https://www.wikipathways.org/WikiPathwaysCurator/InteractionTests/possibleTranslocations