wikipathways-collection

WikiPathways WP4298

• WikiPathways: WP4298 (classic)
• Species: Homo sapiens
• Scholia: WP4298

  Tests

• CASMetabolitesTests: all 2 tests OK!
• ChEBIMetabolitesTests: all 5 tests OK!
• ChemSpiderTests: all 2 tests OK!
• DataNodesTests
  • dataNodesWithoutIdentifier: .x we found 1 problem(s):
    • The following DataNodes have no identifier: 23
  • unknownTypes_knownDatasource: .. all OK!
  • unknownTypes: .. all OK!
  • unknownTypes_Reactome: .. all OK!
  • otherDataSource: .. all OK!
• EnsemblTests: all 4 tests OK!
• GeneTests: all 4 tests OK!
• GeneralTests: all 13 tests OK!
• HMDBSecMetabolitesTests: all 3 tests OK!
• InteractionTests
  • noMetaboliteToNonMetaboliteConversions: .. all OK!
  • noNonMetaboliteToMetaboliteConversions: .. all OK!
  • noGeneProteinConversions: .. all OK!
  • nonNumericIDs: .. all OK!
  • interactionsWithLabels: .x we found 1 problem(s):
    • Interactions found that involve Labels: 50
  • possibleTranslocations: .x we found 1 problem(s):
    • Interactions between identical nodes: 1
  • noProteinProteinConversions: .. all OK!
  • incorrectKEGGIdentifiers: .. all OK!
• KEGGMetaboliteTests: all 2 tests OK!
• LIPIDMAPSTests: all 1 tests OK!
• MetaboliteStructureTests: all 1 tests OK!
• MetabolitesTests: all 14 tests OK!
• OudatedDataSourcesTests: all 8 tests OK!
• PathwayTests: all 7 tests OK!
• ProteinsTests: all 2 tests OK!
• PubChemMetabolitesTests: all 3 tests OK!
• ReferencesTests: all 6 tests OK!
• UniProtTests: all 5 tests OK!
• WikidataTests: all 4 tests OK!

Summary

• Number of test classes: 20
• Number of tests: 99
• Number of assertions: 200
• Number of fails: 3

Fails

Data nodes without an identifier

The following DataNodes have no identifier: 23

http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/cccec (135 S A-particle)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/b3f8b (2A^PRO)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/eb98b (3C^PRO)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/dd6f4 (IgG)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/ea901 (IgG)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/bde2d (MEK 1/2)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/d9564 (MHCII
)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/eac49 (MK2)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/bd4fb (MKK 3/6)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/a915e (MKK 4/7)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/f3e5d (Macrophage
)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/ac79f (Matrix metalloproteinases)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/f6365 (NF-kB)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/af643 (NLRP3)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/d947f (PAR)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/e8d23 (Pro-IL-18)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/a765f (T cell receptor alpha chain V region)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/be2de (T-cell receptor beta chain V region)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/da5cd (Tyrosine kinase)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/a4ca8 (Viral entry
CVB3)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/dde75 (hsp27)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/e6b96 (peptidoglycan muramyl 
dipeptide)
http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/DataNode/d23c9 (pro-IL-1beta)

More details at https://www.wikipathways.org/WikiPathwaysCurator/DataNodesTests/dataNodesWithoutIdentifier

InteractionTests.interactionsWithLabels

Interactions found that involve Labels: 50

http://classic.wikipathways.org/instance/WP4298_r128817 "Increased expr.
? Promotes tissue fibrosis ?
" with graphId e8594
http://classic.wikipathways.org/instance/WP4298_r128817 "antigen" with graphId c7b21
http://classic.wikipathways.org/instance/WP4298_r128817 "HIV" with graphId af64a
http://classic.wikipathways.org/instance/WP4298_r128817 "Myocyte necrosis
Fibrosis
Myocyte atrophy" with graphId cad70
http://classic.wikipathways.org/instance/WP4298_r128817 "Enterovirus-induced 
cardiomyopathy" with graphId b5d55
http://classic.wikipathways.org/instance/WP4298_r128817 "Myocyte dysfunction" with graphId e7ae3
http://classic.wikipathways.org/instance/WP4298_r128817 "Degeneration" with graphId c2dac
http://classic.wikipathways.org/instance/WP4298_r128817 "Chaotic
apoptosis and/or necrosis" with graphId d1968
http://classic.wikipathways.org/instance/WP4298_r128817 "DNA fragmentation
within nucleus" with graphId fbb95
http://classic.wikipathways.org/instance/WP4298_r128817 "Suppresses 
cytopathic 
effects" with graphId cdc0a
http://classic.wikipathways.org/instance/WP4298_r128817 "Cardiac antigens" with graphId cfcfa
http://classic.wikipathways.org/instance/WP4298_r128817 "Sarcomer" with graphId cc327
http://classic.wikipathways.org/instance/WP4298_r128817 "CVB1" with graphId cd959
http://classic.wikipathways.org/instance/WP4298_r128817 "AD2" with graphId b831b
http://classic.wikipathways.org/instance/WP4298_r128817 "Viral antigens" with graphId c772d
http://classic.wikipathways.org/instance/WP4298_r128817 "Decreased force transmission
Increased cell permeability" with graphId a000e
http://classic.wikipathways.org/instance/WP4298_r128817 "Dystrophin deficiency leads to 
loss of the sarcoglycan complex
pre-cursor to DCM" with graphId a213f
http://classic.wikipathways.org/instance/WP4298_r128817 "Decreased expr." with graphId abbf8
http://classic.wikipathways.org/instance/WP4298_r128817 "Mature secreted forms" with graphId dfd16
http://classic.wikipathways.org/instance/WP4298_r128817 "Immune-mediated
myocyte damage" with graphId bab8d
http://classic.wikipathways.org/instance/WP4298_r128817 "Loss of mechanical
stability of the cell" with graphId d9500
http://classic.wikipathways.org/instance/WP4298_r128817 "Viral genomic RNA" with graphId f36cd
http://classic.wikipathways.org/instance/WP4298_r128817 "HIV-2
" with graphId ed8a7
http://classic.wikipathways.org/instance/WP4298_r128817 "Mitochondrion" with graphId a9a73
http://classic.wikipathways.org/instance/WP4298_r128817 "Increased expr." with graphId a7adf
http://classic.wikipathways.org/instance/WP4298_r128817 "HIV-1
" with graphId ea662
http://classic.wikipathways.org/instance/WP4298_r128817 "Matrix degradation" with graphId c2c4e
http://classic.wikipathways.org/instance/WP4298_r128817 "Degradation" with graphId e2591
http://classic.wikipathways.org/instance/WP4298_r128817 "Cell cycle arrest" with graphId d6817
http://classic.wikipathways.org/instance/WP4298_r128817 "Virus-specific 
antibodies" with graphId d8910
http://classic.wikipathways.org/instance/WP4298_r128817 "Primary 
profibrotic 
cytokine" with graphId d1f14
http://classic.wikipathways.org/instance/WP4298_r128817 "Autoreactive
antibodies" with graphId af1dc
http://classic.wikipathways.org/instance/WP4298_r128817 "Viral progeny 
release" with graphId ad04a
http://classic.wikipathways.org/instance/WP4298_r128817 "Actin 
reorganization" with graphId c24c8
http://classic.wikipathways.org/instance/WP4298_r128817 "Cellular activation" with graphId ad96f
http://classic.wikipathways.org/instance/WP4298_r128817 "Overproduction of fibrofatty
 tissue in myocardium" with graphId a9e28
http://classic.wikipathways.org/instance/WP4298_r128817 "Symptomatic arrhythmias" with graphId d64a6
http://classic.wikipathways.org/instance/WP4298_r128817 "Adenovirus
" with graphId e1a6f
http://classic.wikipathways.org/instance/WP4298_r128817 "Coxsackie B virus" with graphId ed816
http://classic.wikipathways.org/instance/WP4298_r128817 "t-Bid" with graphId b7858
http://classic.wikipathways.org/instance/WP4298_r128817 "antigen" with graphId a6c51
http://classic.wikipathways.org/instance/WP4298_r128817 "Host protein synthesis shutoff
induction of CPE" with graphId f09b0
http://classic.wikipathways.org/instance/WP4298_r128817 "CVB3" with graphId e5596
http://classic.wikipathways.org/instance/WP4298_r128817 "Inflammation" with graphId f72d5
http://classic.wikipathways.org/instance/WP4298_r128817 "beta catenin pathway" with graphId da3aa
http://classic.wikipathways.org/instance/WP4298_r128817 "Viral replication, 
inactivation of p21ras" with graphId ad0e2
http://classic.wikipathways.org/instance/WP4298_r128817 "Viral replication" with graphId f0317
http://classic.wikipathways.org/instance/WP4298_r128817 "Antigen presenting cell" with graphId f64c2
http://classic.wikipathways.org/instance/WP4298_r128817 "Max. release of
progeny virion" with graphId dce91
http://classic.wikipathways.org/instance/WP4298_r128817 "Phosphorylated dimers
move to nucleus
stimulate gene expression" with graphId d65f2

Possible MIM translocation

Interactions between identical nodes: 1

http://classic.wikipathways.org/instance/WP4298_r128817 http://rdf.wikipathways.org/Pathway/WP4298_r128817/WP/Interaction/ida31723f6 "Ca2+" (https://identifiers.org/hmdb/HMDB0000464) and 
Ca2+" (https://identifiers.org/hmdb/HMDB0000464)

More details at https://www.wikipathways.org/WikiPathwaysCurator/InteractionTests/possibleTranslocations