wikipathways-collection

WikiPathways WP2447

• WikiPathways: WP2447 (classic)
• Species: Homo sapiens
• Scholia: WP2447

  Tests

• CASMetabolitesTests: all 2 tests OK!
• ChEBIMetabolitesTests: all 5 tests OK!
• ChemSpiderTests: all 2 tests OK!
• DataNodesTests: all 5 tests OK!
• EnsemblTests: all 4 tests OK!
• GeneTests: all 5 tests OK!
• GeneralTests: all 15 tests OK!
• HMDBSecMetabolitesTests: all 3 tests OK!
• InteractionTests
  • noMetaboliteToNonMetaboliteConversions: .. all OK!
  • noNonMetaboliteToMetaboliteConversions: .. all OK!
  • noGeneProteinConversions: .. all OK!
  • nonNumericIDs: .. all OK!
  • interactionsWithLabels: .x we found 1 problem(s):
    • Interactions found that involve Labels: 16
  • UnconnectedPoints: .x we found 1 problem(s):
    • Interactions with unconnected points: 15
  • possibleTranslocations: .x we found 1 problem(s):
    • Interactions between identical nodes: 6
  • noProteinProteinConversions: .. all OK!
  • incorrectKEGGIdentifiers: .. all OK!
• KEGGMetaboliteTests: all 2 tests OK!
• LIPIDMAPSTests: all 1 tests OK!
• MetaboliteStructureTests: all 1 tests OK!
• MetabolitesTests: all 15 tests OK!
• OudatedDataSourcesTests: all 24 tests OK!
• PathwayTests: all 8 tests OK!
• ProteinsTests: all 2 tests OK!
• PubChemMetabolitesTests: all 3 tests OK!
• ReferencesTests: all 6 tests OK!
• UniProtTests: all 5 tests OK!
• UnicodeTests
  • water: .x we found 1 problem(s):
    • Metabolite can use H₂O instead of H2O: 1
• WikidataTests: all 4 tests OK!

Summary

• Number of test classes: 21
• Number of tests: 122
• Number of assertions: 245
• Number of fails: 4

Fails

Interactions with Labels

Interactions found that involve Labels: 16

• http://classic.wikipathways.org/instance/WP2447_r137809 “Accumulation of misfolded proteins” with graphId bedbf
• http://classic.wikipathways.org/instance/WP2447_r137809 “ER stress” with graphId fc1ca
• http://classic.wikipathways.org/instance/WP2447_r137809 “Disturbance of mitochondrial respiration” with graphId c9a4d
• http://classic.wikipathways.org/instance/WP2447_r137809 “ATP depletion Fall in mitochondrial membrane potential” with graphId f7b4d
• http://classic.wikipathways.org/instance/WP2447_r137809 “Increased ROS” with graphId e33d8
• http://classic.wikipathways.org/instance/WP2447_r137809 “Aggregates” with graphId e7ea6
• http://classic.wikipathways.org/instance/WP2447_r137809 “Neuron death” with graphId f875f
• http://classic.wikipathways.org/instance/WP2447_r137809 “DNA” with graphId dfe3d
• http://classic.wikipathways.org/instance/WP2447_r137809 “tBid “ with graphId f559c
• http://classic.wikipathways.org/instance/WP2447_r137809 “Ubiquitin proteosome dysfunction” with graphId af14a
• http://classic.wikipathways.org/instance/WP2447_r137809 “Low Ca2+ buffering capacity” with graphId a6f86
• http://classic.wikipathways.org/instance/WP2447_r137809 “Abnormal Rab5 dependent endycytosis?” with graphId db1b0
• http://classic.wikipathways.org/instance/WP2447_r137809 “Impairment of axonal transport” with graphId e38ad
• http://classic.wikipathways.org/instance/WP2447_r137809 “Aggregates” with graphId d10b5
• http://classic.wikipathways.org/instance/WP2447_r137809 “DNA damage” with graphId accaa
• http://classic.wikipathways.org/instance/WP2447_r137809 “Mitochondria” with graphId b1e57

More details at https://www.wikipathways.org/WikiPathwaysCurator/InteractionTests/interactionsWithLabels

Interactions with unconnected points

Interactions with unconnected points: 15

• http://classic.wikipathways.org/instance/WP2447_r137809

More details at https://www.wikipathways.org/WikiPathwaysCurator/InteractionTests/UnconnectedPoints

Possible MIM translocation

Interactions between identical nodes: 6

• http://classic.wikipathways.org/instance/WP2447_r137809 http://rdf.wikipathways.org/Pathway/WP2447_r137809/WP/Interaction/id3cd23c9 “L-Glutamic acid” (https://identifiers.org/hmdb/HMDB0000148) and L-Glutamic acid” (https://identifiers.org/hmdb/HMDB0000148)
• http://classic.wikipathways.org/instance/WP2447_r137809 http://rdf.wikipathways.org/Pathway/WP2447_r137809/WP/Interaction/id85aed399 “NO” (https://identifiers.org/hmdb/HMDB0003378) and NO” (https://identifiers.org/hmdb/HMDB0003378)
• http://classic.wikipathways.org/instance/WP2447_r137809 http://rdf.wikipathways.org/Pathway/WP2447_r137809/WP/Interaction/idde65c6be “L-Glutamic acid” (https://identifiers.org/hmdb/HMDB0000148) and L-Glutamic acid” (https://identifiers.org/hmdb/HMDB0000148)
• http://classic.wikipathways.org/instance/WP2447_r137809 http://rdf.wikipathways.org/Pathway/WP2447_r137809/WP/Interaction/id6fcdb47 “NO” (https://identifiers.org/hmdb/HMDB0003378) and NO” (https://identifiers.org/hmdb/HMDB0003378)
• http://classic.wikipathways.org/instance/WP2447_r137809 http://rdf.wikipathways.org/Pathway/WP2447_r137809/WP/Interaction/idb3584e45 “NO” (https://identifiers.org/hmdb/HMDB0003378) and NO” (https://identifiers.org/hmdb/HMDB0003378)
• http://classic.wikipathways.org/instance/WP2447_r137809 http://rdf.wikipathways.org/Pathway/WP2447_r137809/WP/Interaction/id8c85cf83 “NO” (https://identifiers.org/hmdb/HMDB0003378) and NO” (https://identifiers.org/hmdb/HMDB0003378)

More details at https://www.wikipathways.org/WikiPathwaysCurator/InteractionTests/possibleTranslocations

Water chemical formula can use Unicode

Metabolite can use H₂O instead of H2O: 1

* [http://classic.wikipathways.org/instance/WP2447_r137809](http://classic.wikipathways.org/instance/WP2447_r137809)

More details at https://www.wikipathways.org/WikiPathwaysCurator/UnicodeTests/water